Focal Nodular Hyperplasia Hepatic Cyst Nodular Regenerative Hyperplasia Hepatocellular Adenoma Central Scar 
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  1. 1.
    Rooks JB, Ory HW, Ishak KG, et al (1979) Epidemiology of hepatocellular adenoma, the role of oral contraceptive use. JAMA 242:644–648PubMedGoogle Scholar
  2. 2.
    Rabe T, Feldmann K, Grunwald K, et al (1994) Liver tumours in women on oral contraceptives. Lancet 344:1568–1569CrossRefPubMedGoogle Scholar
  3. 3.
    Labrune P, Trioche P, Duvaltier I, et al (1997) Hepatocellular adenomas in glycogen storage disease type I and III: A series of 43 patients and review of the literature. J Pediatr Gastroenterol Nutr 24:276–279CrossRefPubMedGoogle Scholar
  4. 4.
    Meissner K (1998) Hemorrhage caused by ruptured liver cell adenoma following long-term oral contraceptives: A case report. Hepatogastroenterology 45:224–225PubMedGoogle Scholar
  5. 5.
    Kawakatsu M, Vilgrain V, Erlinger S, et al (1997) Disappearance of liver cell adenoma: CT and MR imaging. Abdom Imaging 22:274–276CrossRefPubMedGoogle Scholar
  6. 6.
    Craig GR, Peters RL, Edmonson HA (1989) Tumors of the liver and intrahepatic bile ducts. In: Atlas of tumor pathology (2nd series). Armed Forces Institute of Pathology, Washington, DCGoogle Scholar
  7. 7.
    Golli M, Nhieu JTV, Mathieu D, et al (1994) Hepatocellular adenoma: color Doppler US and pathologic correlations. Radiology 190:741–744PubMedGoogle Scholar
  8. 8.
    Bartolozzi C, Lencioni R, Paolicchi A, et al (1997) Differentiation of hepatocellular adenoma and focal nodular hyperplasia of the liver: Comparison of power Doppler imaging and conventional color Doppler sonography. Eur Radiol 7:1410–1415CrossRefPubMedGoogle Scholar
  9. 9.
    Shamsi K, De Schepper A, Degryse H, Deckers F (1993) Focal nodular hyperplasia of the liver: radiologic findings. Abdom Imaging 18:32–38CrossRefPubMedGoogle Scholar
  10. 10.
    Bluemke DA, Soyer P, Fishman EK (1995) Helical (spiral) CT of the liver. Radiol Clin North Am 33: 863–886PubMedGoogle Scholar
  11. 11.
    Ros PR (1990) Computed tomography-pathologic correlations in hepatic tumors. In: Ferrucci JT, Mathieu DG (eds) Advances in hepatobiliary radiology. St Louis, CV Mosby, pp 75–108Google Scholar
  12. 12.
    Paulson EK, McClellan JS, Washington K, et al (1994) Hepatic adenoma: MR characteristics and correlation with pathologic findings. AJR 163:113–116PubMedGoogle Scholar
  13. 13.
    Powers C, Ros PR, Stoupis C, et al (1994) Primary liver neoplasms: MR imaging with pathologic correlation. Radiographics 14:459–482PubMedGoogle Scholar
  14. 14.
    Arrive L, Flejou J-F, Vilgrain V, et al (1994) Hepatic adenoma: MR findings in 51 pathologically proved lesions. Radiology 193:507–512PubMedGoogle Scholar
  15. 15.
    Chung KY, Mayo-Smith WW, Saini S, et al (1995) Hepatocellular adenoma: MR imaging features with pathologic correlation. AJR Am J Roentgenol 165:303–308PubMedGoogle Scholar
  16. 16.
    Chen KT, Bocian JJ (1983) Multiple hepatic adenomas. Arch Pathol Lab Med 107:274–275PubMedGoogle Scholar
  17. 17.
    Nguyen BN, Flejou JF, Terris B, et al (1999) Focal nodular hyperplasia of the liver: A comprehensive pathologic study of 305 lesions and recognition of new histologic forms. Am J Surg Pathol 23:1441–1454PubMedGoogle Scholar
  18. 18.
    Kondo F (2000) Focal nodular hyperplasia of the liver: Controversy over etiology. J Gastrcenterol Hepatol 15:1229–1231CrossRefGoogle Scholar
  19. 19.
    Mathieu D, Kobeiter H, Maison P, et al (2000) Oral contraceptive use and focal nodular hyperplasia of the liver. Gastrcenterology 118:560–564Google Scholar
  20. 20.
    Nisenbaum HL, Rowling SE (1995) Ultrasound of focal hepatic lesions. Semin Roentgenol 30:324–346PubMedGoogle Scholar
  21. 21.
    Buetow PC, Pantongrag-Brown L, Buck JL, et al (1996) Focal nodular hyperplasia of the liver: radiologic-pathologic correlation. Radiographics 16:369–388PubMedGoogle Scholar
  22. 22.
    Lee M, Hamm B, Saini S (1991) Focal nodular hyperplasia of the liver: MR findings in 35 proved cases. AJR Am J Roentgenol l56:317–320Google Scholar
  23. 23.
    Shirkhoda A, Farah MC, Bernacki E, et al (1994) Hepatic focal nodular hyperplasia: CT and sonographic spectrum. Abdom Imaging 19:34–38PubMedGoogle Scholar
  24. 24.
    Mahfouz A-E, Hamm B, Taupiz M, et al (1993) Hypervascular liver lesions: differentiation of focal nodular hyperplasia from malignant tumors with dynamic gadolinium-enhanced MR imaging. Radiology 186:133–138PubMedGoogle Scholar
  25. 25.
    Grandin C, Van Beers BE, Robert A, et al (1995) Benign hepatocellular tumors: MRI after superparamagnetic iron oxide administration. J Comput Assist Tomogr 19:412–418PubMedGoogle Scholar
  26. 26.
    Paley MR, Mergo PJ, Ros PR (1997) Characterization of focal liver lesions with SPIO-enhanced T2WI: patterns of signal intensity and liver lesion contrast change. Radiology 205(P):455–456Google Scholar
  27. 27.
    Mathieu D, Vilgrain V, Mahfouz A-E, et al (1997) Benign liver tumors. MRI Clin North Am 5:255–258Google Scholar
  28. 28.
    Dachman AH, Ros PR, Goodman ZD, et al (1987) Nodular regenerative hyperplasia of the liver: clinical and radiologic observations. AJR 148:717–722PubMedGoogle Scholar
  29. 29.
    Naber AH, Van Haelst U, Yap SH (1991) Nodular regenerative hyperplasia of the liver: An important cause of portal hypertension in non-cirrhotic patients. J Hepatol 12:94–99CrossRefPubMedGoogle Scholar
  30. 30.
    Portmann B, Stewart S, Higenbottam TW et al (1993) Nodular transformation of the liver associated with portal and pulmonary arterial hypertension. Gastroenterology 104:616–621PubMedGoogle Scholar
  31. 31.
    Dumortier J, Boillot O, Chevallier M, et al (1999) Familial occurrence of nodular regenerative hyperplasia of the liver: A report on three families. Gut 45:289–294PubMedGoogle Scholar
  32. 32.
    Stomeyer FW, Ishak KG (1981) Nodular transformation (nodular “regenerative” hyperplasia) of the liver. A clinico-pathologic study of 30 cases. Hum Pathol 12:60–71PubMedGoogle Scholar
  33. 33.
    Vilgrain V, Lewin M, Vons C, et al (1999) Hepatic nodules in Budd-Chiari syndrome: imaging features. Radiology 210:443–450PubMedGoogle Scholar
  34. 34.
    Brancatelli G, Federle MP, Grazioli L, Golfieri R, Lencioni R (2002) Large regenerative nodules in Budd-Chiari syndrome and other vascular disorders of the liver: CT and MR imaging findings with clinicopathologic correlation. AIR Arm J Roentgenoll 78:877–883Google Scholar
  35. 35.
    Nakanuma Y, Hoso M, Sasaki M, et al (1996) Histopathology of the liver in non-cirrhotic portal hypertension of unknown aetiology. Histopathology 28:195–204CrossRefPubMedGoogle Scholar
  36. 36.
    Nakanuma Y (1990) Nodular regenerative hyperplasia of the liver: Retrospective survey in autopsy series. J Clin Gastroenterol 12:460–465PubMedGoogle Scholar
  37. 37.
    Casillas C, Marti-Bonmati L, Galant J (1997) Pseudotumoral presentation of nodular regenerative hyperplasia of the liver: Imaging in five patients including MR imaging. Eur Radiol 7:654–658PubMedGoogle Scholar
  38. 38.
    Clouet M, Boulay I, Boudiaf M, et al (1999) Imaging features of nodular regenerative hyperplasia of the liver mimicking hepatic metastases. Abdom Imaging 24:258–261CrossRefPubMedGoogle Scholar
  39. 39.
    Siegelman ES, Outwater EK, Furth EE, et al (1995) MR imaging of hepatic nodular regenerative hyperplasia. J Magr Reson Imaging 5:730–732Google Scholar
  40. 40.
    Rha SE, Lee MG, Lee YS, et al (2000) Nodular regenerative hyperplasia of the liver in BuddChiari syndrome: CT and MR features. Abdom Imaging 25:255–258CrossRefPubMedGoogle Scholar
  41. 41.
    Goodman ZD (1987) Benign tumors of the liver. In: Okuda K. Ishak KG (eds) Neoplasms of the liver. Springer. Tokyo, pp 105–125Google Scholar
  42. 42.
    International Working Party (1995) Terminology of nodular hepatocellular lesions. Hepatology 25:983–993Google Scholar
  43. 43.
    Sakamoto M, Hirohashi S, Shimosato Y (1991) Early stages of multistep hepatocarcinogenesis: Adenomatous hyperplasia and early hepatocellular carcinoma. Hum Pathol 22:172–178CrossRefPubMedGoogle Scholar
  44. 44.
    Maetani Y, Itoh K, Egawa H, et al (2002) Benign hepatic nodules in Budd-Chiari syndrome: radiologic-pathologic correlation with emphasis on the central scar. AIR Am 1 Roentgenol 178:869–875Google Scholar
  45. 45.
    Ferrell LD, Crawford JM, Dhillon AP, Scheuer PJ, Nakanuma Y (1993) Proposal for standardized criteria for the diagnosis of benign, borderline, and malignant hepatocellular lesions arising in chronic advanced liver disease. Am J Surg Pathol 17:1113–1123PubMedGoogle Scholar
  46. 46.
    Choi BI, Han JK, Hong SH, et al (1999) Dysplastic nodules of the liver: imaging findings. Abdorn Irnmaging 24:250–257CrossRefGoogle Scholar
  47. 47.
    Rode A, Bancel B, Douek P, et al (2001) Small nodule detection in cirrhotic livers: evaluation with US, spiral CT, and MRI and correlation with pathologic examination of explanted liver. J Comput Assist Tomogr 25:327–336CrossRefPubMedGoogle Scholar
  48. 48.
    Efremidis SC, Hytiroglou P (2002) The multistep process of hepatocarcinogenesis in cirrhosis with imaging correlation. Eur Radiol 12:753–764CrossRefPubMedGoogle Scholar
  49. 49.
    Earls JP, Theise ND, Weinreb JC, et al (1996) Dysplastic nodules and hepatocellular carcinoma: thin-section MR imaging of explanted cirrhotic livers with pathologic correlation. Radiology 201:207–214PubMedGoogle Scholar
  50. 50.
    Murphy BJ, Casillas J, Ros PR, et al (1989) The CT appearance of cystic masses of the liver. RadioGraphics 9:307–322PubMedGoogle Scholar
  51. 51.
    Buetow PC, Buck JL, Pantongrag-Brown L, et al (1995) Biliary cystadenoma and cystadenocarcinoma: Clinical-imaging-pathologic correlation with emphasis on the importance of ovarian stroma. Radiology 196:805–810PubMedGoogle Scholar
  52. 52.
    Mathieu D, Paret M, Mahfouz AE, et al (1997) Hyperintense benign liver lesions on spinecho Tl-weighted MR images: Pathologic correlations. Abdom Imaging 22:410–417CrossRefPubMedGoogle Scholar
  53. 53.
    Desmet VJ (1998) Ludwig Symposium on Biliary Disorders-part I. Pathogenesis of ductal plate abnormalities. Mayo Clin Proc 73:80–89PubMedGoogle Scholar
  54. 54.
    Principe A, Lugaresi ML, Lords RC, et al (1997) Bile duct hamartomas: Diagnostic problems and treatment. Hepatogas-troenterology 44:994–997Google Scholar
  55. 55.
    Lev-Toaff AS, Bach AM, Wechsler RJ, et al (1995) The radiologic and pathologic spectrum of biliary hamartomas. AJR Am J Roentgenol 165:309–313PubMedGoogle Scholar
  56. 56.
    Cooke JC, Cooke DA (1987) The appearances of multiple biliary hamartomas of the liver (von Meyenberg complexes) on computed tomography. Clin Radiol 38:101–102CrossRefPubMedGoogle Scholar
  57. 57.
    Slone HW, Bennett WF, Bova JG (1993) MR findings of multiple biliary hamartomas. AJR Am J Roentgenol 161:581–583PubMedGoogle Scholar
  58. 58.
    Semelka RC, Hussain SM, Marcos HB, et al (1999) Biliary hamartomas: Solitary and multiple lesions shown on current MR techniques including gadolinium enhancement. J Magn Reson Imaging 10:196–201CrossRefPubMedGoogle Scholar
  59. 59.
    Choi BI, Lim HJ, Han MC, et al (1989) Biliary cystadenoma and cystadenocarcinoma: CT and sonographic findings. Radiology 171:57–61PubMedGoogle Scholar
  60. 60.
    Stoupis C, Ros PR, Dolson DJ (1994) Recurrent biliary cystadenoma: MR imaging appearance. J Magn Reson Imaging 4:99–101PubMedGoogle Scholar
  61. 61.
    Dachman AH, Lichenstein JE, Friedman AC, et al (1983) Infantile hemangioendothelioma of the liver: a radiologic-pathologic-clinical correlation. AJR 140:1091–1096PubMedGoogle Scholar
  62. 62.
    Allaire GS, Rabin L, Ishak KG, Sesterhenn IA (1988) Bile duct adenoma: A study of 152 cases. Am J Surg Pathol 12:708–715PubMedGoogle Scholar
  63. 63.
    Bhathal PS, Hughes NR, Goodman ZD (1996) The so-called bile duct adenoma is a peribiliary gland hamartoma. Am J Surg Pathol 20:858–864CrossRefPubMedGoogle Scholar
  64. 64.
    Tajima T, Honda H, Kuroiwa T, et al (1999) Radiologic features of intrahepatic bile duct adenoma: a look at the surface of the liver. J Comput Assist Tomogr 23:690–695CrossRefPubMedGoogle Scholar
  65. 65.
    Ros PR, Lubbers PR, Olmsted WW, et al (1987) Hemangioma of the liver: magnetic resonance — gross morphologic correlation. AJR 149:1167–1170PubMedGoogle Scholar
  66. 66.
    Karhunen PJ (1986) Benign hepatic tumors and tumor-like conditions in men. J Clin Pathol 39:183–188PubMedGoogle Scholar
  67. 67.
    Gandolfi L, Leo P, Solmi L, et al (1991) Natural history of hepatic haemangiomas: Clinical and ultrasound study. Gut 32:677–680PubMedGoogle Scholar
  68. 68.
    Kim TK, Han JK, Kim AY, et al (1999) Limitations of characterization of hepatic hemangiomas using a sonographic contrast agent (Levovist) and power Doppler ultrasonography. J Ultrasound Med 18:737–743PubMedGoogle Scholar
  69. 69.
    Leslie DE, Johnson CD, Johnson CM, et al (1995) Distinction between cavernous hemangiomas of the liver and hepatic metastases on CT: value of contrast enhancement patterns. AJR 164:625–629PubMedGoogle Scholar
  70. 70.
    Itai Y, Ohtomo K, Furui S, et al (1985) Noninvasive diagnosis of small cavernous hemangioma of the liver: advantage of MRI. AJR 145:1195–1199PubMedGoogle Scholar
  71. 71.
    Ferrucci JT (1986) MR imaging of the liver. AJR 147:1103–1116PubMedGoogle Scholar
  72. 72.
    Yoshida H, Itai Y, Ohtomo K, et al (1989) Small hepatocellular carcinoma and cavernous hemangioma: differentiation with dynamic FLASH MR imaging with Gd-DTPA. Radiology 171:339–342PubMedGoogle Scholar
  73. 73.
    Ohtomo K, Itai Y, Yoshikawa K, et al (1987) Hepatic tumors: dynamic MR imaging. Radiology 163:27–31PubMedGoogle Scholar
  74. 74.
    Semelka RC, Brown ED, Ascher SM, et al (1994) Hepatic hemangiomas: a multi-institutional study of appearances on T2-weighted and serial gadolinium-enhanced gradient-echo MR images. Radiology 192:401–406PubMedGoogle Scholar
  75. 75.
    Whitney WS, Herfkens RJ, Jeffrey RB, et al (1993) Dynamic breath-hold multiplanar spoiled gradient-recalled MR imaging with gadolinium enhancement for differentiating hepatic hemangiomas from malignancies at 1.5 T. Radiology 189:863–870PubMedGoogle Scholar
  76. 76.
    McFarland EG, Mayo-Smith WW, Saini S, et al (1994) Hepatic hemangiomas and malignant tumors: improved differentiation with heavily T2-weighted conventional spin-echo MR imaging. Radiology 193:43–47PubMedGoogle Scholar
  77. 77.
    Semelka RC, Sofka CM (1997) Hepatic hemangiomas. MRI Clin North Am 5:241–253Google Scholar
  78. 78.
    Mitchell DG, Saini S, Weinreb J, et al (1994) Hepatic metastases and cavernous hemangiomas: distinction with standard and triple-dose Gadoteridol-enhanced MR imaging. Radiology 193:49–57PubMedGoogle Scholar
  79. 79.
    Soyer P, Gueye C, Somerveille E, et al (1995) MR diagnosis of hepatic metastases from neuroendocrine tumors versus hemangiomas: relative merits of dynamic gadolinium chelate-enhanced gradient-recalled echo and unenhanced spin-echo images. AJR Am J Roentgenol 165:1407–1413PubMedGoogle Scholar
  80. 80.
    Saini S, Edelman RR, Sharma P, et al (1995) Blood-pool MR contrast material for detection and characterization of focal hepatic lesions: initial clinical experience with ultra-small superparamagnetic iron oxide (AMI-227). AJR 164:1147–1152PubMedGoogle Scholar
  81. 81.
    Ros PR (1991) Focal liver masses other than metastases. In: Gore RM (ed) Syllabus for categorical course on gastrointestinal radiology. American College of Radiology. Reston, Va. pp 159–169Google Scholar
  82. 82.
    Mortele KJ, Mergo PJ, Urrutia M, et al (1998) Dynamic gadolinium-enhanced MR findings in infantile hepatic heman-gioendothelioma. J Comput Assist Tomogr 22:714–717CrossRefPubMedGoogle Scholar
  83. 83.
    Helmberger TK, Ros PR, Mergo PJ, Tomczak R, Reiser MF (1999) Pediatric liver neoplasms: a radiologic-pathologic correlation. Eur Radiol 9:1339–1347CrossRefPubMedGoogle Scholar
  84. 84.
    Pobiel RS, Bisset GS 3rd. (1995) Pictorial essay: imaging of liver tumors in the infant and child. Pediatr Radiol 25:495–506PubMedGoogle Scholar
  85. 85.
    Stocker JT, Ishak KG (1983) Mesenchymal hamartoma of the liver: report of 30 cases and review of the literature. Pediatr Pathol 1: 245–267PubMedGoogle Scholar
  86. 86.
    Mortele KJ, Vanzieleghem B, Mortele B, Benoit Y, Ros PR (2002) Solitary hepatic infantile hemangioendothelioma: dynamic gadolinium-enhanced MR imaging findings. Eur Radiol 12:862–865CrossRefPubMedGoogle Scholar
  87. 87.
    Ros PR, Goodman ZD, Ishak KG, et al (1986) Mesenchymal hamartoma of the liver: radiologic-pathologic correlation. Radiology 158:619–624PubMedGoogle Scholar
  88. 88.
    O’Neill J, Ros PR (1989) Knowing hepatic pathology aids MRI of liver tumors. Diagn Imaging 19:558–67Google Scholar
  89. 89.
    Sato M, Ishida H, Konno K, et al (2000) Liver tumors in children and young patients: sonographic and color Doppler findings. Abdom Imaging 25:596–601CrossRefPubMedGoogle Scholar
  90. 90.
    Goodman ZD, Ishak KG (1984) Angiomyolipomas of the liver. Am J Surg Pathol 8:745–750PubMedGoogle Scholar
  91. 91.
    Roberts JL, Fishman EK, Hartman DS, et al (1986) Lipomatous tumors of the liver: evaluation with CT and US. Radiology 158:613–617PubMedGoogle Scholar
  92. 92.
    Ros PR (1994) Hepatic angiomyolipoma: is fat in the liver friend or foe? Abdom Imaging 19:552–553CrossRefPubMedGoogle Scholar
  93. 93.
    Hogemann D, Flemming P, Kreipe H, Galanski M (2001) Correlation of MRI and CT findings with histopathology in hepatic angiomyolipoma. Eur Radiol 11: 1389–1395CrossRefPubMedGoogle Scholar
  94. 94.
    Murakami T, Nakamura H, Hori S, et al (1993) Angiomyolipoma of the liver. Ultrasound, CT, MR imaging and angiography. Acta Radiol 34:392–394PubMedGoogle Scholar
  95. 95.
    O’Sullivan DA, Torres VE, de Groen PC, Batts KP, King BF, Vockley J (1998) Hepatic lymphangiomatosis mimicking polycystic liver disease. Mayo Clin Proc 73:1188–1192PubMedGoogle Scholar
  96. 96.
    Wachsberg RH, Cho KC, Adekosan A (1994) Two leomyomas of the liver in an adult with AIDS: CT and MR appearance. J Comput Assist Tomogr 18:156–157PubMedGoogle Scholar
  97. 97.
    Mobini J, Krouse TB, Cooper DR (1974) Intrahepatic pancreatic heterotopia. Review and report of a case presenting as an abdominal mass. Am J Dis 19:64–70CrossRefGoogle Scholar
  98. 98.
    Lecesne R, Drouillard J, Le Bail B, Saric J, Balabaud C, Laurent F (1998) Localized fibrous tumor of the liver: imaging findings. Eur Radiol 8:36–38CrossRefPubMedGoogle Scholar
  99. 99.
    Tajima T, Funakoshi A, Ikeda Y, et al (2001) Nonfunctioning adrenal rest tumor of the liver: radiologic appearance. J Comput Assist Tomogr 25:98–101CrossRefPubMedGoogle Scholar
  100. 100.
    Ros PR (1998) Hepatic imaging. Radiol Clin North Am 36:237–246CrossRefPubMedGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 2005

Authors and Affiliations

  • Hoon Ji
  • Pablo R. Ros

There are no affiliations available

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