Array Formats

  • Ralph R. Martel
  • Matthew P. Rounseville
  • Ihab W. Botros
  • Bruce E. Seligmann
Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)


Array Element Multiplex Assay Array Technology Array Format Aqueous Subphase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Lockhart DJ, Dong H, Byrne MC, Follettie MT, Gallo MV, Chee MS, Mittmann M, Wang C, Kobayashi M, Horton H, Brown EL (1996) Expression monitoring by hybridization to high-density oligonucleotide arrays. Nat Biotechnol 14:1675–80PubMedCrossRefGoogle Scholar
  2. 2.
    Wodicka L, Dong H, Mittmann M, Ho MH, Lockhart DJ (1997) Genome-wide expression monitoring in Saccharomyces cerevisiae. Nat Biotechnol 15:1359–67PubMedCrossRefGoogle Scholar
  3. 3.
    Schweitzer B, Kingsmore SF (2002) Measuring proteins on microarrays. Curr Opin Biotechnol 13:14–9PubMedCrossRefGoogle Scholar
  4. 4.
    Love KR, Seeberger PH (2002) Carbohydrate arrays as tools for glycomics. Angew Chem Int Ed Engl 41:3583–6, 3513PubMedCrossRefGoogle Scholar
  5. 5.
    Lam KS, Renil M (2002) From combinatorial chemistry to chemical microarray. Curr Opin Chem Biol 6:353–8PubMedCrossRefGoogle Scholar
  6. 6.
    Wu RZ, Bailey SN, Sabatini DM (2002) Cell-biological applications of transfected-cell microarrays. Trends Cell Biol 12:485–8PubMedCrossRefGoogle Scholar
  7. 7.
    Fejzo MS, Slamon DJ (2001) Frozen tumor tissue microarray technology for analysis of tumor RNA, DNA, and proteins. Am J Pathol 159:1645–50PubMedGoogle Scholar
  8. 8.
    Yang L, Tran DK, Wang X (2001) BADGE, Beads Array for the Detection of Gene Expression, a high-throughput diagnostic bioassay. Genome Res 11:1888–98PubMedGoogle Scholar
  9. 9.
    Tung WS, Lee JK, Thompson RW (2001) Simultaneous analysis of 1176 gene products in normal human aorta and abdominal aortic aneurysms using a membrane-based complementary DNA expression array. J Vasc Surg 34:143–50PubMedCrossRefGoogle Scholar
  10. 10.
    Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP, Coller H, Loh ML, Downing JR, Caligiuri MA, Bloomfield CD, Lander ES (1999) Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 286:531–7PubMedCrossRefGoogle Scholar
  11. 11.
    Hedenfalk I, Duggan D, Chen Y, Radmacher M, Bittner M, Simon R, Meltzer P, Gusterson B, Esteller M, Kallioniemi OP, Wilfond B, Borg A, Trent J (2001) Gene-expression profiles in hereditary breast cancer. N Engl J Med 344:539–48PubMedCrossRefGoogle Scholar
  12. 12.
    Heller RA, Schena M, Chai A, Shalon D, Bedilion T, Gilmore J, Woolley DE, Davis RW (1997) Discovery and analysis of inflammatory disease-related genes using cDNA microarrays. Proc Natl Acad Sci USA 94:2150–5PubMedCrossRefGoogle Scholar
  13. 13.
    Blackwell HE, Perez L, Stavenger RA, Tallarico JA, Cope Eatough E, Foley MA, Schreiber SL (2001) A one-bead, one-stock solution approach to chemical genetics: part 1. Chem Biol 8:1167–82PubMedCrossRefGoogle Scholar
  14. 14.
    LeProust E, Pellois JP, Yu P, Zhang H, Gao X, Srivannavit O, Gulari E, Zhou X (2000) Digital light-directed synthesis. A microarray platform that permits rapid reaction optimization on a combinatorial basis. J Comb Chem 2:349–54PubMedCrossRefGoogle Scholar
  15. 15.
    Fodor SP, Read JL, Pirrung MC, Stryer L, Lu AT, Solas D (1991) Light-directed, spatially addressable parallel chemical synthesis. Science 251:767–773PubMedGoogle Scholar
  16. 16.
    David CA, Middleton T, Montgomery D, Lim HB, Kati W, Molla A, Xuei X, Warrior U, Kofron JL, Burns DJ (2002) Microarray compound screening (microARCS) to identify inhibitors of HIV integrase. J Biomol Screen 7:259–66PubMedGoogle Scholar
  17. 17.
    Heller JH (2002) DNA microarray technology: devices, systems, and applications. Annu Rev Biomed Eng 4:129–53PubMedCrossRefGoogle Scholar
  18. 18.
    Shoemaker DD, Linsley PS (2002) Recent developments in DNA microarrays. Curr Opin Microbiol 5:334–337PubMedCrossRefGoogle Scholar
  19. 19.
    Oliphant A, Barker DL, Stuelpnagel JR, Chee MS (2002) BeadArray technology: enabling an accurate, cost-effective approach to high-throughput genotyping. Biotechniques Suppl 32:56–61Google Scholar
  20. 20.
    Umek RM, Lin SW, Vielmetter J, Terbrueggen RH, Irvine B, Yu CJ, Kayyem JF, Yowanto H, Blackburn GF, Farkas DH, Chen YP (2001) Electronic detection of nucleic acids: a versatile platform for molecular diagnostics. J Mol Diagn 3:74–84PubMedGoogle Scholar
  21. 21.
    Velculescu VE, Zhang L, Vogelstein B, Kinzler KW (1995) Serial Analysis of Gene Expression. Science 270: 484–487PubMedGoogle Scholar
  22. 22.
    Bertelson AH, Velculescu VE (1998) High-throughput Gene Expression Analysis Using SAGE. Drug Discovery Today 3:152–159CrossRefGoogle Scholar
  23. 23.
    Haab BB, Dunham MJ, Brown PO (2001) Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions. Genome Biol 2:research0004.1-0004.13Google Scholar
  24. 24.
    Kodadek T (2002) Development of protein-detecting microarrays and related devices. Trends Biochem Sci 27:295–300PubMedCrossRefGoogle Scholar
  25. 25.
    Martel RR, Botros IW, Rounseville MP, Hinton JP, Staples RR, Morales DA, Farmer JB, Seligmann BE (2002) Multiplexed screening assay for mRNA combining nuclease protection with luminescent array detection. Assay Drug Dev Tech 1:61–71CrossRefGoogle Scholar
  26. 26.
    Berk AJ, Sharp PA (1977) Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell 12:721–32PubMedCrossRefGoogle Scholar
  27. 27.
    Maxwell IH, Van Ness J, Hahn WE (1978) Assay of DNA-RNA hybrids by S1 nuclease digestion and adsorption to DEAE-cellulose filters. Nucleic Acids Res 5:2033–8PubMedGoogle Scholar
  28. 28.
    Wittelsberger SC, Hansen JN (1977) The specificity of S1 nuclease toward RNA-DNA hybrids as studied using isotopes of phosphorus-32 and phosphorus-33. Nucleic Acids Res 4:1829–35PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2005

Authors and Affiliations

  • Ralph R. Martel
  • Matthew P. Rounseville
  • Ihab W. Botros
  • Bruce E. Seligmann

There are no affiliations available

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