Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Altman JD, Trendelenburg AU, MacMillan L, Bernstein D, Limbird L, Starke K, Kobilka BK, Hein L. (1999) Abnormal sympathetic α2-autoreceptor function in α2A-adrenergic receptor knockout mice. Mol. Pharmacol. 56, 154–161
Brede M, Hadamek L, Meinel L, Wiesmann F, Peters J, Engelhardt S, Simm A, Lohse MJ, Hein L (2001) Vascular hypertrophy and increased P70S6 kinase in mice lacking the angiotensin II AT2 receptor. Circulation 104, 2602–2607
Brede M, Wiesmann F, Jahns R, Hadamek K, Arnolt C, Neubauer S, Lohse MJ, Hein L (2002) Feedback inhibition of catecholamine release by two different α2-adrenoceptor subtypes prevents progression of heart failure. Circulation 106, 2491–2496
Brede M, Nagy G, Philipp M, Sørensen J, Lohse MJ, Hein L (2003). Differential control of adrenal and sympathetic catecholamine release by α2-adrenergic receptor subtypes. Mol. Endocrinol. 17, 1640–1646
Bylund DB, Bond RA, Clarke DE, Eikenburg DC, Hieble JP, Langer SZ, Lefkowitz RJ, Minneman KP, Molinoff PB, Ruffolo RR, Strosberg AD, Trendelenburg UG (1998) Adrenoceptors. In: The IUPHAR compendium of receptor characterization and classification, IUPHAR Media. London, pp 58–74
Carson RP, Robertson D (2002) Genetic manipulation of noradrenergic neurons. J Pharmacol Exp Ther 301: 410–417
Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162. 156–159
Chruscinski A, Brede ME, Meinel L, Lohse MJ, Kobilka BK, Hein L (2001) Differential distribution of β-adrenergic receptor subtypes in blood vessels of knockout mice lacking β1-or β2-adrenergic receptors. Mol Pharmacol 60: 955–962
Desai KH, Sato R, Schauble E, Barsh GS, Kobilka BK, Bernstein D (1997) Cardiovascular indexes in the mouse at rest and with exercise: new tools to study models of cardiac disease. Am J Physiol. 272, H1053–H1061
Engelhardt S, Hein L, Wiesmann F, Lohse MJ (1999) Progressive hypertrophy and heart failure in β1-adrenergic receptor transgenic mice. Proc Natl Acad Sci USA 96: 7059–7064
Engelhardt S, Boknik P, Keller U, Neumann J, Lohse MJ, Hein L (2001a) Early impairment of calcium handling and altered expression of junction in hearts of mice overexpressing the β1-adrenergic receptor. Faseb J. 15: 2718–2720
Georgakopoulos D, Mitzner WA, Chen CH, Byrne BJ, Millar HD, Hare JM, Kass DA (1998) In vivo murine left ventricular pressure-volume relations by miniaturized conductance micromanometry. Am J Physiol 274, H1416–H1422
Halbrugge T, Gerhardt T, Ludwig J, Heidbreder E, Graefe KH (1988) Assay of catecholamines and dihydroxyphenylethyleneglycol in human plasma and its application in orthostasis and mental stress. Life Sci. 43, 19–26
Hein L, Barsh GS, Pratt RE, Dzau VJ, Kobilka BK (1995) Behavioural and cardiovascular effect of disrupting the angiotensin II type-2 receptor gene in mice. Nature 377, 744–747
Hogan B, Costantini F, Lacy E (1986) Manipulating the mouse embryo. A laboratory manual. Cold Spring Harbor Laboratory, 1986
Kaumann AJ, Engelhardt S, Hein L, Molenaar P, Lohse M (2001) Abolition of (-)-CGP 12177-evoked cardiostimulation in double β1/β2-adrenoceptor knockout mice. Obligatory role of β1-adrenoceptors for putative β4-adrenoceptor pharmacology. Naunyn Schmiedeberg’s Arch Pharmacol 363: 87–93
Link RE, Desai K, Hein L, Stevens ME, Chruscinski A, Bernstein D, Barsh GS, Kobilka BK (1996) Cardiovascular regulation in mice lacking a2-adrenergic receptor subtypes b and c. Science 273, 803–805
Mulvany MJ, Halpern W (1976) Mechanical properties of vascular smooth muscle cells in situ. Nature 260, 617–619
Nicol T, Vernon-Roberts B, Quantock DC (1965) Protective effect of oestrogens against the toxic decomposition products of tribromoethanol. Nature 208, 1098–1099
Paris A, Philipp M, Steinfath M, Tonner P, Lohse MJ, Scholz J, Hein L (2003) Activation of α2B-adrenoceptors mediates cardiovascular effects of etomidate. Anesthesiology 99: 889–895
Philipp M, Brede M, Hein L (2002) Physiological significance of α2-adrenergic receptor subtype diversity: one receptor is not enough. Am J Physiol 283: R287–R295
Rohrer DK (2000) Targeted disruption of adrenergic receptor genes. Methods Mol Biol 126: 259–277
Walsh PS; Metzger DA, Higuchi R (1991) Chelex-100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. BioTechniques 10: 506–513
Wiesmann F, Ruff J, Engelhardt S, Hein L, Dienesch C, Leupold A, Illinger R, Frydrychowicz A, Hiller KH, Rommel E, Haase A, Lohse MJ, Neubauer S (2001) Dobutamine stress magnetic resonance microimaging in mice: Acute changes of cardiac geometry and function in normal and failing murine hearts. Circ. Res. 88, 563–569
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Brede, M., Philipp, M., Hein, L. (2005). Measurement of Function and Regulation of Adrenergic Receptors. In: Dhein, S., Mohr, F.W., Delmar, M. (eds) Practical Methods in Cardiovascular Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26574-0_41
Download citation
DOI: https://doi.org/10.1007/3-540-26574-0_41
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-40763-8
Online ISBN: 978-3-540-26574-0
eBook Packages: MedicineMedicine (R0)