Abstract
Regeneration of tissue is a fundamental parameter of liver response to injury and is essential for postoperative recovery from hepatic resection. An adequate microvascular supply of remnant tissue and new forming cell clusters is necessary for the precise reconstitution of the organ. In the present study we analyzed for the first time the hepatic architecture and microcirculation of the regenerated liver at 3, 5, and 8 days after partial hepatectomy (68%) in mice using intravital fluorescence micro-scopy. The assessed data may contribute to a better understanding of the complex vascular and cellular mechanisms during liver regeneration after partial hepatectomy.
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Literatur
Michalopoulos GK, DeFrances MC (1997) Liver regeneration. Science 276:60–66
Kountouras J, Boura P, Lygidakis NJ (2001) Liver regeneration after hepatectomy. Hepatogastroenterology 48:556–562
Greene AK, Puder M (2003) Partial hepatectomy in the mouse: technique and perioperative management. J Invest Surg 16:99–102
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© 2005 Springer Medizin Verlag Heidelberg
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Dallmann, K., Eipel, C., Menger, M.D., Vollmar, B. (2005). In vivo Analyse der hepatischen Architektur und Mikrozirkulation der regenerierenden Mausleber nach partieller Hepatektomie. In: Rothmund, M., Jauch, KW., Bauer, H. (eds) Chirurgisches Forum 2005. Deutsche Gesellschaft für Chirurgie, vol 34. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26560-0_86
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DOI: https://doi.org/10.1007/3-540-26560-0_86
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-24888-0
Online ISBN: 978-3-540-26560-3
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