Prostaglandin Metabolism and Effects of Inhibitors

  • Karsten Schrör


Arachidonic Acid Aminosalicylic Acid Ductus Closure Prostaglandin Receptor Persist Ductus Arteriosus 


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  1. Morris JL, Rosen DA, Rosen KR: Nonsteroidal anti-inflammatory agents in neonates. Pediatr Drugs 2003; 5: 385–405.Google Scholar
  2. Hahn EL, He LK, Gamelli RL: Prostaglandin E2 synthesis and metabolism in burn injury and trauma. J Trauma 2000; 49: 1147–54.PubMedCrossRefGoogle Scholar
  3. Loftin CD, Tiano HF, Langenbach R: Phenotypes of the COX-deficient mice indicate physiological and pathophysiological roles for COX-1 and COX-2. Prostaglandins Other Lipid Mediat 2002; 68–69: 177–85.PubMedGoogle Scholar
  4. Baragatti B, Brizzi F, Ackerley C, Barogi S, Ballou LR, Coceani F: Cyclooxygenase-1 and cyclooxygenase-2 in the mouse ductus arteriosus: individual activity and functional coupling with nitric oxide synthase. Br J Pharmacol 2003; 139: 1505–15.CrossRefPubMedGoogle Scholar
  5. Norton ME, Merrill J, Cooper BA, Kuller JA, Clyman RI: Neonatal complications after the administration of indomethacin for preterm labor. N Engl J Med 1993; 329: 52–63.CrossRefGoogle Scholar
  6. Campbell WB, Halushka PV: Lipid-derived autoacids: Ecosanoids and platelet-activating factor. In Goodman and Gilman’s the pharmacological basis of therapeutics, 9th edition 1996: 601–616, (eds. Hardman JG et al.), McGraw-Hill, New York, NY.Google Scholar

Copyright information

© Springer Medizin Verlag Heidelberg 2005

Authors and Affiliations

  • Karsten Schrör
    • 1
  1. 1.Institute for Pharmacology and Clinical PharmacologyHeinrich-Heine-UniversitätDüsseldorf

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