Skip to main content
  • 590 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 34.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Adams SS, Bresloff P, Mason CG. Pharmacological differences between the optical isomers of ibuprofen: Evidence for metabolic inversion of the (-)-isomer. J Pharm Pharmacol 1976; 28:256–7.

    PubMed  CAS  Google Scholar 

  2. Heyman E, Morag I, Batash D, Keidar R, Baram S, Berkovitch M. Closure of patent ductus arteriosus with oral ibuprofen suspension in premature newborns: A pilot study. Pediatrics 2003; 112:e354–8.

    Article  PubMed  Google Scholar 

  3. Patel J, Marks KA, Roberts I, Azzopardi D, Edwards AD. Ibuprofen treatment of patent ductus arteriosus. Lancet 1995; 346:255.

    PubMed  CAS  Google Scholar 

  4. Varvarigou A, Bardin CL, Beharry K, Chemtob S, Papageorgiou A, Aranda JV. Early ibuprofen administration to prevent patent ductus arteriosus in premature newborn infants. JAMA 1996; 275:539–44.

    Article  PubMed  CAS  Google Scholar 

  5. Van Overmeire B, Follens I, Hartmann S, Creten WL, Van Acker KJ. Treatment of patent ductus arteriosus with ibuprofen. Arch Dis Child 1997; 76:F179–84.

    Google Scholar 

  6. Van Overmeire B, Smets K, Lecoutere D, Van de Broek H, Weyler J, De Groote K, Langhendries J-P. A comparison of ibuprofen and indomethacin for closure of patent ductus arteriosus. N Engl J Med 2000; 343:674–81.

    Article  PubMed  Google Scholar 

  7. Ohlsson A, Walia R, Shah S. Ibuprofen for the treatment of a patent ductus arteriosus in preterm and/or low birth weight infants (Cochrane Review). The Cochrane Library 2003; Issue 2, Oxford.

    Google Scholar 

  8. Shah SS, Ohlsson A. Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants (Cochrane Review). The Cochrane Library 2003; Issue 2, Oxford.

    Google Scholar 

  9. Gournay V, Savagner C, Thiriez G, Kuster A, Rozé J-C. Pulmonary hypertension after ibuprofen prophylaxis in very preterm infants. Lancet 2002; 359: 1486–8.

    Article  PubMed  CAS  Google Scholar 

  10. Schmidt B, Wright LL, Davis P, Solimano A, Roberts RS. Ibuprofen prophylaxis in preterm neonates. Lancet 2002; 360: 492.

    PubMed  Google Scholar 

  11. Van Overmeire B, Casaer A, Allegaert K, Debauche C, Decaluwe W, Jespers A, Weyler J, Langhendries JP. Multicenter randomized double-blind placebo controlled trial of ibuprofen prophylaxis in very preterm infants. Pediatr Res 2002; 51: 379A.

    Google Scholar 

  12. Fowlie PW, Davis PG. Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants (Cochrane Review). The Cochrane Library 2003; Issue 1 2003. Oxford.

    Google Scholar 

  13. Schmidt B, Davis P, Moddemann D, Ohlsson A, Roberts RS, Saigal S, Solimano A, Vincer M, Wright LL, for the Trial of Indomethacin Prophylaxis in Preterms Investigators. Long-term effects of indomethacin prophylaxis in extremely-low-birth-weight infants. N Engl J Med 2001; 344: 1966–72.

    Article  PubMed  CAS  Google Scholar 

  14. Pezzati M, Vangi V, Biagiotti R, Bertini G, Cianciulli D, Rubaltelli FF. Effects of indomethacin and ibuprofen on mesenteric and renal blood flow in preterm infants with patent ductus arteriosus. J Pediatr 1999; 135: 733–8.

    PubMed  CAS  Google Scholar 

  15. Guignard JP. The adverse renal effects of prostaglandin-synthesis inhibitors in the newborn rabbit. Semin Perinatol 2002; 26: 398–405.

    PubMed  Google Scholar 

  16. Mosca F, Bray M, Lattanzio M, Fumagalli M, Tosetto C. Comparative evaluation of the effects of indomethacin and ibuprofen on cerebral perfusion and oxygenation in preterm infants with patent ductus arteriosus. J Pediatr 1997; 131: 549–54.

    PubMed  CAS  Google Scholar 

  17. Naulaers G, Delanghe G, Allegaert K, Casaer P, Devlieger H, Van Overmeire B. Randomized double-blind controlled trial comparing the effects of ibuprofen with placebo on cerebral hemodynamics. Pediatr Res 2002; 51: 338A.

    Google Scholar 

  18. Van Overmeire B, Touw D, Schepens PJC, Kearns GL, van den Anker JN. Ibuprofen pharmacokinetics in preterm infants with patent ductus arteriosus. Clin Pharmacol Ther 2001; 70: 336–43.

    PubMed  Google Scholar 

  19. Cooper-Peel C, Brodersen R, Robertson A. Does ibuprofen affect bilirubin-albumin binding in newborn infant serum?. Pharmacol Toxicol 1996; 79: 297–9.

    Article  PubMed  CAS  Google Scholar 

  20. Ahlfors CE. Effect of ibuprofen on bilirubin-albumin binding. J Pediatr 2004; 144: 386–8.

    PubMed  CAS  Google Scholar 

  21. Su, PH, Chen JY, Su CM, Huang TC, Lee HS. Comparison of ibuprofen and indomethacin therapy for patent ductus arteriosus in preterm infants. Pediatr Int 2003; 45: 665–70.

    Article  PubMed  CAS  Google Scholar 

  22. Gregoire N, Gualano V, Geneteau A, Millerioux L, Brault M, Mignot A, Roze JC. Population pharmacokinetics of ibuprofen enantiomers in very premature naonates. J Clin Pharmacol 2004; 44: 1114–24.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer Medizin Verlag Heidelberg

About this chapter

Cite this chapter

van Overmeire, B. (2005). Comparison of Indomethacin and Ibuprofen. In: Obladen, M., Koehne, P. (eds) Interventions for Persisting Ductus Arteriosus in the Preterm Infant. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26509-0_13

Download citation

  • DOI: https://doi.org/10.1007/3-540-26509-0_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-24511-7

  • Online ISBN: 978-3-540-26509-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics