Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Donaldson SS, Jundt S, Ricour C, Sarrazin D, Lemerle J, Schweisguth O (1975) Radiation enteritis in children. A retrospective review, clinicopathologic correlation, and dietary management. Cancer 351167–1178
Chao N, Levine J, Horning SJ (1987) Retroperitoneal fibrosis following treatment for Hodgkin's disease. J Clin Oncol 5:231–232
Heyn R, Raney RB, Jr., Hays DM et al. (1992) Late effects of therapy in patients with paratesticular rhabdomyosarcoma. Intergroup Rhabdomyosarcoma Study Committee. J Clin Oncol 10:614–623
Hughes LL, Baruzzi MJ, Ribeiro RC et al. (1994) Paratesticular rhabdomyosarcoma: delayed effects of multimodality therapy and implications for current management. Cancer 73:476–482
Kaplinsky C, Kornreich L, Tiomny E, Cohen IJ, Loven D, Zaizov R (1991) Esophageal obstruction 14 years after treatment for Hodgkin's disease. Cancer 68:903–905
Mahboubi S, Silber JH (1997) Radiation-induced esophageal strictures in children with cancer. Eur Radiol 7:119–122
Papazian A, Capron JP, Ducroix JP, Dupas JL, Quenum C, Besson P (1983) Mucosal bridges of the upper esophagus after radiotherapy for Hodgkin's disease. Gastroenterology 84:1028–1031
Raney B Jr, Heyn R, Hays DM et al. (1993) Sequelae of treatment in 109 patients followed for 5 to 15 years after diagnosis of sarcoma of the bladder and prostate. A report from the Intergroup Rhabdomyosarcoma Study Committee. Cancer 71:2387–2394
Deeg HJ, Storb R, Thomas ED (1984) Bone marrow transplantation: a review of delayed complications. Br J Haematol 57:185–208
Fisher VL (1999) Long-term follow-up in hematopoietic stem-cell transplant patients. Pediatr Transplant 3[Suppl 1]:122–129
Knapp AB CJ, Rappeport JM, Gollan JL (1987) Cirrhosis as a consequence of graft versus host disease. Gastroenterology 92:513–519
Locasciulli A, Bacigalupo A, van Lint MT et al. (1990) Hepatitis B virus (HBV) infection and liver disease after allogeneic bone marrow transplantation: a report of 30 cases. Bone Marrow Transplant 6:25–29
Locasciulli A, Gornati G, Tagger A et al. (1991) Hepatitis C virus infection and chronic liver disease in children with leukemia in long-term remission. Blood 78:1619–1622
Locasciulli A, Testa M, Valsecchi MG et al. (1997) Morbidity and mortality due to liver disease in children undergoing allogeneic bone marrow transplantation: a 10-year prospective study. Blood 90:3799–3805
Paul IM, Sanders J, Ruggiero F, Andrews T, Ungar D, Eyster ME (1999) Chronic hepatitis C virus infections in leukemia survivors: prevalence, viral load, and severity of liver disease. Blood 93:3672–3677
Socie G, Stone JV, Wingard JR et al. (1999) Long-term survival and late deaths after allogeneic bone marrow transplantation. Late Effects Working Committee of the International Bone Marrow Transplant Registry. N Engl J Med 341:14–21
Strickland DK, Jenkins JJ, Hudson MM (2001) Hepatitis C infection and hepatocellular carcinoma after treatment of childhood cancer. J Pediatr Hematol Oncol 23:527–529
Castellino S, Lensing S, Riely CA et al. (2004) The epidemiology of chronic hepatitis C infection in survivors of childhood cancer — an update of the St. Jude Children's Research Hospital hepatitis C seropositive cohort. Blood 103:2460–2466
Yau JC, Zander AR, Srigley JR et al. (1986) Chronic graftversushost disease complicated by micronodular cirrhosis and esophageal varices. Transplantation 41:129–130
Strasser SI, Sullivan KM, Myerson D et al. (1999) Cirrhosis of the liver in long-term marrow transplant survivors. Blood 93:3259–3266
Fajardo L (1989) Radiation-induced pathology of the alimentary tract. In: Whitehead R (ed) Gastrointestinal and oesophageal pathology. Churchill Livingstone, Edinburgh
Shulman H (1990) Pathology of chronic graft-vs.-host disease. In: Burakoff S (ed) Graft-vs-host disease immunology, pathophysiology and treatment. Dekker, New York
Bhatia S, et al. (2003) High risk of second malignant neoplasms continues with extended follow-up of childhood Hodgkin's disease: Report from the Late Effects Study Group. J Clin Oncol (in press)
Metayer C, Lynch CF, Clarke EA et al. (2000) Second cancers among long-term survivors of Hodgkin's disease diagnosed in childhood and adolescence. J Clin Oncol 18:2435–2443
Swerdlow AJ, Barber JA, Hudson GV et al. (2000) Risk of second malignancy after Hodgkin's disease in a collaborative British cohort: the relation to age at treatment. J Clin Oncol 18:498–509
Roswit B (1974) Complications of radiation therapy: the alimentary tract. Semin Roentgenol 9:51–63
Berthrong M, Fajardo LF (1981) Radiation injury in surgical pathology. Part II. Alimentary tract. Am J Surg Pathol 5:153–178
Localio SA, Stone A, Friedman M (1969) Surgical aspects of radiation enteritis. Surg Gynecol Obstet 129:1163–1172
Emami B, Lyman J, Brown A et al. (1991) Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 21:109–122
Donaldson SS, Glatstein E, Rosenberg SA, Kaplan HS (1976) Pediatric Hodgkin's disease. II. Results of therapy. Cancer 37:2436–2447
Tefft M (1977) Radiation related toxicities in National Wilms'Tumor Study Number 1. Int J Radiat Oncol Biol Phys 2:455–463
Seaman WB, Ackerman LV (1957) The effect of radiation on the esophagus; a clinical and histologic study of the effects produced by the betatron. Radiology 68:534–541
Lepke RA, Libshitz HI (1983) Radiation-induced injury of the esophagus. Radiology 148:375–378
Goldstein HM, Rogers LF, Fletcher GH, Dodd GD (1975) Radiological manifestations of radiation-induced injury to the normal upper gastrointestinal tract. Radiology 117:135–140
Orringer MB, Sloan H (1978) Monilial esophagitis: an increasingly frequent cause of esophageal stenosis? Ann Thorac Surg 26:364–374
Simson JN, Kinder RB, Isaacs PE, Jourdan MH (1985) Mucosal bridges of the oesophagus in Candida oesophagitis. Br J Surg 72:209–210
Horwich A, Lokich JJ, Bloomer WD (1975) Doxorubicin, radiotherapy, and oesophageal stricture. Lancet 2:561–562
Newburger PE, Cassady JR, Jaffe N (1978) Esophagitis due to adriamycin and radiation therapy for childhood malignancy. Cancer 42:417–423
Phillips TL, Fu KK (1976) Quantification of combined radiation therapy and chemotherapy effects on critical normal tissues. Cancer 37[Suppl 2]:1186–1200
Boal DK, Newburger PE, Teele RL (1979) Esophagitis induced by combined radiation and adriamycin. AJR Am J Roentgenol 132:567–570
Tefft M, Lattin PB, Jereb B et al. (1976) Acute and late effects on normal tissues following combined chemo-and radiotherapy for childhood rhabdomyosarcoma and Ewing's sarcoma. Cancer 37[Suppl 2]:1201–1217
Meyers PA, Potter VP, Wollner N, Exelby P (1985) Bowel perforation during initial treatment for childhood non-Hodgkin's lymphoma. Cancer 56:259–261
Wobbes T, Verschueren RC, Lubbers EJ, Jansen W, Paping RH (1984) Surgical aspects of radiation enteritis of the small bowel. Dis Colon Rectum 27:89–92
Ritchey ML, Kelalis PP, Breslow N et al. (1992) Surgical complications after nephrectomy for Wilms’ tumor. Surg Gynecol Obstet 175:507–514
Jockovich M, Mendenhall NP, Sombeck MD, Talbert JL, Copeland EM 3rd, Bland KI (1994) Long-term complications of laparotomy in Hodgkin's disease. Ann Surg 219:615–621; discussion 621–614
Hays DM, Ternberg JL, Chen TT et al. (1986) Postsplenectomy sepsis and other complications following staging laparotomy for Hodgkin's disease in childhood. J Pediatr Surg 21:628–632
Hays DM, Ternberg JL, Chen TT et al. (1984) Complications related to 234 staging laparotomies performed in the Intergroup Hodgkin's Disease in Childhood study. Surgery 96:471–478
Kaiser CW (1981) Complications from staging laparotomy for Hodgkin disease. J Surg Oncol 16:319–325
Smith IE, Peckham MJ, McElwain TJ, Gazet JC, Austin DE (1977) Hodgkin's disease in children. Br J Cancer 36:120–129
Green DM, Ghoorah J, Douglass HO Jr et al. (1983) Staging laparotomy with splenectomy in children and adolescents with Hodgkin's disease. Cancer Treat Rev 10:23–38
Lanzkowsky P, Shende A, Karayalcin G, Aral I (1976) Staging laparotomy and splenectomy: treatment and complications of Hodgkin's disease in children. Am J Hematol 1:393–404
Filler RM, Jaffe N, Cassady JR, Traggis DG, Vawter GF (1975) Experience with clinical and operative staging of Hodgkin's disease in children. J Pediatr Surg 10:321–328
Cohen IT, Higgins GR, Powars DR, Hays DM (1977) Staging laparotomy for Hodgkin's disease in children. Evaluation of the technique. Arch Surg 112:948–951
Bell MJ, Land VJ, Ternberg JL (1977) Staging laparotomy for Hodgkin's disease in children. Am J Surg 133:582–583
Zinchke H, Segura JW (1975) Ureterosigmoidostomy: critical review of 173 cases. J Urol 113:324–327
Bristol JB, Williamson RC (1981) Ureterosigmoidostomy and colon carcinogenesis. Science 214:351
Gittes RF (1986) Carcinogenesis in ureterosigmoidostomy. Urol Clin North Am 13:201–205
McDonald GB, Sullivan KM, Schuffler MD, Shulman HM, Thomas ED (1981) Esophageal abnormalities in chronic graft-versus-host disease in humans. Gastroenterology 80:914–921
McDonald GB, Sullivan KM, Plumley TF (1984) Radiographic features of esophageal involvement in chronic graft-vs.-host disease. AJR Am J Roentgenol 142:501–506
Screening for colorectal cancer (2004). United States Preventive Services Task Force. Available at: http://www.ahrq.gov/clinic/uspstfix.htm.Acessed September 28
Smith RA, Cokkinides V, Eyre HJ (Jan–Feb 2004) American Cancer Society guidelines for the early detection of cancer, 2004. CA Cancer J Clin 54(1): 41–52
Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancers. CureSearch Children's Oncology Group. March 2004
Patrick RS, McGee JOD (1980) Biopsy pathology of the liver. Chapman Hall, London
Shulman HM, Sullivan KM, Weiden PL et al. (1980) Chronic graft-versus-host syndrome in man. A long-term clinicopathologic study of 20 Seattle patients. Am J Med 69:204–217
Tsoi MS, Storb R, Jones E et al. (1978) Deposition of IgM and complement at the dermoepidermal junction in acute and chronic cutaneous graft-vs-host disease in man. J Immunol 120:1485–1492
Blatt J, Olshan A, Gula MJ, Dickman PS, Zaranek B (1992) Second malignancies in very-long-term survivors of childhood cancer. Am J Med 93:57–60
Ingold JA RG, Kaplan HS, Bagshaw MA (1965) Radiation hepatitis. Am J Roentgenol 93:200–208
Jirtle RL, Alati T (1990) Radiation sensitivity of the liver. Adv Radiat Biol 14:269–311
Tefft M, Jaffe MA (1971) Irradiation of the liver in children: acute effects enhanced by concomitant chemotherapeutic administration. Am J Roentgenol Rad Ther Nucl Med 111:165–173
Tefft M MA, Das L, Vawter GF, Filler RM (1970) Irradiation of the liver in children: review of the experience in the acute and chronic phases, and in the intact normal and partially resected. Am J Roentgenol Rad Ther Nucl Med 108:365–385
Kun LE, Camitta BM (1978) Hepatopathy following irradiation and adriamycin. Cancer 42:81–84
Bhanot P, Cushing B, Philippart A, Das L, Farooki Z (1979) Hepatic irradiation and adriamycin cardiotoxicity. J Pediatr 95:561–563
Johnson FL (1982) Hepatopathy following irradiation and chemotherapy for Wilms’ tumor. Am J Pediatr Hematol Oncol 4:217–221
Flentje M, Weirich A, Potter R, Ludwig R (1994) Hepatotoxicity in irradiated nephroblastoma patients during postoperative treatment according to SIOP9/GPOH. Radiother Oncol 31:222–228
Barnard JA MG, Neblett WW, Gray G, Ghishan FK (1986) Noncirrhotic portal fibrosis after Wilms’ tumor therapy. Gastroenterology 90:1054–1056
Perry M (1992) Chemotherapeutic agents and hepatotoxicity. Semin Oncol 19:551–565
Locasciulli A, Vergani GM, Uderzo C et al. (1983) Chronic liver disease in children with leukemia in long-term remission. Cancer 52:1080–1087
Weber BL, Tanyer G, Poplack DG et al. (1987) Transient acute hepatotoxicity of high-dose methotrexate therapy during childhood. NCI Monogr 5:207–212
Bessho F, Kinumaki H, Yokota S, Hayashi Y, Kobayashi M, Kamoshita S (1994) Liver function studies in children with acute lymphocytic leukemia after cessation of therapy. Med Pediatr Oncol 23:111–115
Ballauff A, Krahe J, Jansen B, Ross RS, Roggendorf H, Havers W (1999) Chronic liver disease after treatment of malignancies in children. Klin Pediatr 211:49–52
Lascari AD, Givler RL, Soper RT, Hill LF (1968) Portal hypertension in a case of acute leukemia treated with antimetabolites for ten years. N Engl J Med 279:303–306
Ruymann FB, Mosijczuk AD, Sayers RJ (1977) Hepatoma in a child with methotrexate-induced hepatic fibrosis. JAMA 238:2631–2633
Nesbit M, Krivit W, Heyn R, Sharp H (1976) Acute and chronic effects of methotrexate on hepatic, pulmonary, and skeletal systems. Cancer 37[Suppl 2]:1048–1057
Einhorn M DI (1964) Hepatotoxicity of mercaptopurine. JAMA 188:102–106
Green DM, Norkool P, Breslow NE, Finklestein JZ, D'Angio GJ (1990) Severe hepatic toxicity after treatment with vincristine and dactinomycin using single-dose or divideddose schedules: a report from the National Wilms’ Tumor Study. J Clin Oncol 8:1525–1530
Raine J, Bowman A, Wallendszus K, Pritchard J (1991) Hepatopathy-thrombocytopenia syndrome — a complication of dactinomycin therapy for Wilms’ tumor: a report from the United Kingdom Childrens Cancer Study Group. J Clin Oncol 9:268–273
Parker D, Bate CM, Craft AW, Graham-Pole J, Malpas JS, Stansfeld AG (1980) Liver damage in children with acute leukaemia and non-Hodgkin's lymphoma on oral maintenance chemotherapy. Cancer Chemother Pharmacol 4:121–127
McIntosh S DD, O'Brien RT, Pearson HA (1977) Methotrexate hepatotoxicity in children with leukemia. J Pediatr 90:1019–1021
Topley JM, Squier MV, Chessells JM (1979) Hepatotoxicity in the treatment of acute lymphoblastic leukemia. Med Pediatr Oncol 7:393–399
Hutter RVP, Tan CTC, Murphy ML, Chowdhury M (1960) Hepatic fibrosis in children with acute leukemia: a complication of therapy. Cancer 13:288–307
Colsky J, Warren TN (1955) Hepatic fibrosis in children with acute leukemia after therapy with folic acid antagonists. Arch Pathol Lab Med 59:198–206
Hersh EM WV, Henderson ES, Freireich E (1966) Hepatotoxic effects of methotrexate. Cancer 19:600–606
Farthing MJG, Sloane JP (1982) Liver disease after bone marrow transplantation. Gut 23:465–474
Shulman HM, McDonald DB (1984) Liver disease after marrow transplantation. In: Sale GE, Shulman HM (eds) The pathology of bone marrow transplantation. Year Book Medical Publishers, Chicago, pp 104–135
Zecca M, Prete A, Rondelli R et al. (2002) Chronic graftversushost disease in children: incidence, risk factors, and impact on outcome. Blood 100:1192–1200
Sullivan KM, Agura E, Anasetti C et al. (1991) Chronic graft-versus-host disease and other late complications of bone marrow transplantation. Semin Hematol 28:250–259
Seeff LB, Koff RS (1986) Evolving concepts of the clinical and serologic consequences of hepatitis B virus infection. Semin Liver Dis 6:11–22
Strickland DK, Riely CA, Patrick CC et al. (2000) Hepatitis C infection among survivors of childhood cancer. Blood 95:3065–3070
Fink FM, Hocker-Schulz S, Mor W et al. (1993) Association of hepatitis C virus infection with chronic liver disease in paediatric cancer patients. Eur J Pediatr 152:490–492
Villano SA, Vlahov D, Nelson KE, Cohn S, Thomas DL (1999) Persistence of viremia and the importance of longterm follow-up after acute hepatitis C infection. Hepatology 29:908–914
Arico M, Maggiore G, Silini E et al. (1994) Hepatitis C virus infection in children treated for acute lymphoblastic leukemia. Blood 84:2919–2922
Cesaro S, Rossetti F, de Moliner L, Crivellaro C, Zanesco L, Bortolotti F (1994) Interferon for chronic hepatitis C in patients cured of malignancy. Eur J Pediatr 153:659–662
Cesaro S, Petris MG, Rossetti F et al. (1997) Chronic hepatitis C virus infection after treatment for pediatric malignancy. Blood 90:1315–1320
Locasciulli A, Alberti A, Barbieri R et al. (1983) Evidence of non-A, non-B hepatitis in children with acute leukemia and chronic liver disease. Am J Dis Child 137:354–356
Locasciulli A, Bacigalupo A, Vanlint MT et al. (1991) Hepatitis C virus infection in patients undergoing allogeneic bone marrow transplantation. Transplantation 52:315–318
Locasciulli A, Cavalletto D, Pontisso P et al. (1993) Hepatitis C virus serum markers and liver disease in children with leukemia during and after chemotherapy. Blood 82:2564–2567
Locasciulli A, Pontisso P, Cavalletto D et al. (1994) Evidence against the role of hepatitis C virus in severe liver damage occurring early in the course of acute leukemia in children. Leuk Lymph 13:119–122
Locasciulli A, Testa M, Pontisso P et al. (1997) Prevalence and natural history of hepatitis C infection in patients cured of childhood leukemia. Blood 90:4628–4633
Locasciulli A, Testa M, Pontisso P et al. (1997) Hepatitis C virus genotypes and liver disease in patients undergoing allogeneic bone marrow transplantation. Bone Marrow Transplant 19:237–240
Lucidarme D DF, Arpurt J et al. (1997) Natural history of hepatitis C: age at the time of transfusion might be an important predictive factor of progression to cirrhosis. Gastroenterology 112:A361
Swilley S SD, Davila R, Levstik M, Ribeiro R, Hudson MM (2002) Hepatitis C infection during treatment for childhood cancer: pitfalls in diagnosis and management. Med Pediatr Oncol 39:58–59
Vogt M, Lang T, Frosner G et al. (1999) Prevalence and clinical outcome of hepatitis C infection in children who underwent cardiac surgery before the implementation of blood-donor screening. N Engl J Med 341:866–870
Neilson JR, Harrison P, Skidmore SJ, King JA, Collingham KE, Milligan DW (1996) Chronic hepatitis C in long term survivors of haematological malignancy treated in a single centre. J Clin Pathol 49:230–232
Gigliotti AR, Fioredda F, Giacchino R (2003) Hepatitis B and C infection in children undergoing chemotherapy or bone marrow transplantation. J Pediatr Hematol Oncol 25:184–192
Poynard T, Bedossa P, Opolon P (1997) Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups. Lancet 349:825–832
Goedert JJ, Eyster ME, Lederman MM et al. (2002) Endstage liver disease in persons with hemophilia and transfusion-associated infections. Blood 100:1584–1589
Franchini M, Rossetti G, Tagliaferri A et al. (2001) The natural history of chronic hepatitis C in a cohort of HIV-negative Italian patients with hereditary bleeding disorders. Blood 98:1836–1841
Liang TJ, Rehermann B, Seeff LB, Hoofnagle JH (2000) Pathogenesis, natural history, treatment, and prevention of hepatitis C. Ann Intern Med 132:296–305
Mahmoud H, Schell M, Pui CH (1991) Cholelithiasis after treatment for childhood cancer. Cancer 67:1439–1442
Chu WC, Roebuck DJ (2003) Nodular regenerative hyperplasia of the liver simulating metastases following treatment for bilateral Wilms tumor. Med Pediatr Oncol 41:85–87
Wanless IR (1990) Micronodular transformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2,500 autopsies and a new classification of benign hepatocellular nodules. Hepatology 11:787–797
Kumagai H, Masuda T, Oikawa H, Endo K, Endo M, Takano T (2000) Focal nodular hyperplasia of the liver: direct evidence of circulatory disturbances. J Gastroenterol Hepatol 15:1344–1347
Bouyn CI, Leclere J, Raimondo G et al. (2003) Hepatic focal nodular hyperplasia in children previously treated for a solid tumor. Incidence, risk factors, and outcome. Cancer 97:3107–3113
Brisse H, Servois V, Bouche B et al. (2000) Hepatic regenerating nodules: a mimic of recurrent cancer in children. Pediatr Radiol 30:386–393
Halonen P, Mattila J, Ruuska T, Salo MK, Makipernaa A (2003) Liver histology after current intensified therapy for childhood acute lymphoblastic leukemia: microvesicular fatty change and siderosis are the main findings. Med Pediatr Oncol 40:148–154
Bernard B, Lebrec D, Mathurin P, Opolon P, Poynard T (1997) Propranolol and sclerotherapy in the prevention of gastrointestinal rebleeding in patients with cirrhosis: a meta-analysis. J Hepatol 26:312–324
Bernard B, Lebrec D, Mathurin P, Opolon P, Poynard T (1997) Beta-adrenergic antagonists in the prevention of gastrointestinal rebleeding in patients with cirrhosis: a meta-analysis. Hepatology 25:63–70
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Hudson, M.M. (2005). Late Gastrointestinal and Hepatic Effects. In: Schwartz, C.L., Hobbie, W.L., Constine, L.S., Ruccione, K.S. (eds) Survivors of Childhood and Adolescent Cancer. Pediatric Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26498-1_12
Download citation
DOI: https://doi.org/10.1007/3-540-26498-1_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-40840-6
Online ISBN: 978-3-540-26498-9
eBook Packages: MedicineMedicine (R0)