Molecular Pathology Laboratory of the Future

  • Christopher A. Moskaluk
Part of the Principles and Practice book series (PRINCIPLES)


Prostate Biopsy Surgical Pathology Prostatic Adenocarcinoma Polymerase Chain Reac Tissue Diagnosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Duggan DJ, Bittner M, Chen Y, Meltzer P, Trent JM (1999) Expression profiling using cDNA microarrays. Nature Genetics 21(1 Suppl):10–14PubMedGoogle Scholar
  2. Emmert-Buck MR, Strausberg RL, Krizman DB, Bonaldo MF, Bonner RF, Bostwick DG, Brown MR, Buetow KH, Chuaqui RF, Cole KA, Duray PH, Englert CR, Gillespie JW, Greenhut S, Grouse L, Hillier LW, Katz KS, Klausner RD, Kuznetzov V, Lash AE, Lennon G, Linehan WM, Liotta LA, Marra MA, Munson PJ, Ornstein DK (2000) Molecular profiling of clinical tissue specimens: feasibility and applications. Am J Pathol 156:1109–1115PubMedGoogle Scholar
  3. Fechner RE (1997). The birth and evolution of American surgical pathology. In: Rosai J (ed) Guiding the surgeon’s hand; the history of American surgical pathology. American Registry of Pathology. Washington, DC, pp 7–21Google Scholar
  4. Giordano TJ, Shedden KA, Schwartz DR, Kuick R, Taylor JM, Lee N, Misek DE, Greenson IK, Kardia SL, Beer DG, Rennert G, Cho KR, Gruber SB, Fearon ER, Hanash S (2001) Organ-specific molecular classification of primary lung, colon, and ovarian adenocarcinomas using gene expression profiles. Am J Pathol 159(4):1231–1238PubMedGoogle Scholar
  5. Goldenberg MM (1999) Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer. Clin Ther 21(2):309–318CrossRefPubMedGoogle Scholar
  6. Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov IP, Coller H, Loh ML, Downing 1R, Caligiuri MA, Bloomfield CD, Lander ES (1999) Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 286(5439):531–537CrossRefPubMedGoogle Scholar
  7. Hanna W, Kahn HJ, Trudeau M (1999) Evaluation of HER-2/neu (erbB-2) status in breast cancer: from bench to bedside. Modern Pathol 12(8):827–834Google Scholar
  8. Lipshutz RJ, Fodor SP, Gingeras TR, Lockhart DJ (1999) High density synthetic oligonucleotide arrays. Nat Genet 21(1 Suppl):20–24PubMedGoogle Scholar
  9. Pusztai L, Ayers M, Stec J, Hortobagyi GN (2003) Clinical application of cDNA microarrays in oncology. Oncologist 8(3):252–258CrossRefPubMedGoogle Scholar
  10. Ramaswamy S, Tamayo P, Rifkin R, Mukherjee S, Yeang CH, Angelo M, Ladd C, Reich M, Latulippe E, Mesirov JP, Poggio T, Gerald W, Loda M, Lander ES, Golub TR (2001) Multiclass cancer diagnosis using tumor gene expression signatures. Proc Natl Acad Sci USA 98(26):15149–15154CrossRefPubMedGoogle Scholar
  11. Rosai J (1997) Some considerations on the origin, evolution, and outlook of American surgical pathology. In: Rosai J (ed) Guiding the surgeon’s hand; the history of American surgical pathology. American Registry of Pathology. Washington, DC, pp 1–5Google Scholar
  12. Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL (1987) Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235:177–182PubMedGoogle Scholar
  13. Su AI, Welsh JB, Sapinoso LM, Kern SG, Dimitrov P, Lapp H, Schultz PG, Powell SM, Moskaluk CA, Frierson HF Jr., Hampton GM (2001) Molecular classification of human carcinomas by use of gene expression signatures. Cancer Res 61(20):7388–7393PubMedGoogle Scholar

Copyright information

© Springer Berlin Heidelberg 2005

Authors and Affiliations

  • Christopher A. Moskaluk

There are no affiliations available

Personalised recommendations