Neonatal Hypoxic-Ischemic Encephalopathy

  • Fabio Triulzi
  • Cristina Baldoli
  • Andrea Righini


Hypoxic-ischemic encephalopathy (HIE) is the major recognized perinatal cause of neurological morbidity both in premature and full-term newborns [1]. During the perinatal period, hypoxemia and/or ischemia usually occur as a result of asphyxia; brain biochemical changes associated with hypoxemia, ischemia, and asphyxia are extremely complex and, other than to duration and severity of the event, are strictly related to the state of brain development and maturation.


Perinatal Asphyxia Neonatal Brain Lentiform Nucleus Deep Gray Matter Apparent Diffusion Coefficient Image 
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© Springer-Verlag Berlin Heidelberg 2005

Authors and Affiliations

  • Fabio Triulzi
    • 1
  • Cristina Baldoli
    • 2
  • Andrea Righini
    • 1
  1. 1.Department of Radiology and NeuroradiologyV. Buzzi Children’s HospitalMilanItaly
  2. 2.Department of NeuroradiologySan Raffaele Scientifi c InstituteMilanItaly

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