Diffusion-Weighted, Perfusion-Weighted, and Functional MR Imaging

  • Ernst Martin-Fiori
  • Thierry A. G. M. Huisman


Over the last decades, magnetic resonance imaging (MRI) has revolutionized our understanding of the dynamics of organ morphology and physiology in health and disease. In conventional MRI, most of the signal arises from differences in the amount of bulk water between tissues, and image contrast is determined by T1 and T2 relaxation mechanisms that originate from interactions on a molecular level, either between water protons or via exchange with protons at the surface of macromolecules. Therefore, image contrast of a tissue or organ structure appears rather homogeneous on conventional MRI.


White Matter Apparent Diffusion Coefficient Fractional Anisotropy Cerebral Blood Volume Blood Oxygenation Level Dependent 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2005

Authors and Affiliations

  • Ernst Martin-Fiori
    • 1
  • Thierry A. G. M. Huisman
    • 2
  1. 1.Neuroradiology & Magnetic Resonance, Department of Diagnostic ImagingUniversity Children’s HospitalZurichSwitzerland
  2. 2.Department of Diagnostic Imaging Radiology and NeuroradiologyUniversity Children’s Hospital ZurichZurichSwitzerland

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