Abstract
Myelination is a very important process of brain maturation because it is essential for neural impulses transmission. It is a dynamic process that starts during fetal life and proceeds predominantly after birth, at least until the end of the third year, in a well-defined, predetermined manner [1–3].
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References
Dietrich RB, Bradley WG, Zaragoza EJ 4th, Otto RJ, Taira RK, Wilson GH, Kangarloo H. MR evaluation of early myelination patterns in normal and developmentally delayed infants. AJNR Am J Neuroradiol 1988; 9:69–76.
Martin E, Kikinis R, Zuerrer M, Boesch C, Briner J, Kewitz G, Kaelin P. Developmental stages of human brain: an MR study. J Comput Assist Tomogr 1988; 12:917–922.
Staudt M, Schropp C, Staudt F, Obletter N, Bise K, Breit A. Myelination of the brain in MR: a staging system. Pediatr Radiol 1993; 23:169–176.
Barkovich AJ, Kjos BO, Jackson DE, Norman D. Normal maturation of the neonatal and infant brain: MR imaging at 1.5T. Radiology 1988; 166:173–180.
Barkovich AJ. Concepts of myelin and myelination in neuroradiology. AJNR Am J Neuroradiol 2000; 21:1099–1109.
Hayakawa K, Konishi Y, Kuriyama M, Konishi K, Matsuda T. Normal brain maturation in MRI. Eur J Radiol 1990; 12:208–215.
Korogi Y, Takahashi M, Sumi M, Hirai T, Sakamoto Y, Ikushima I, Miyayama H. MR signal intensity of the perirolandic cortex in the neonate and infant. Neuroradiology 1996; 38:578–584.
McArdle CB, Richardson CJ, Nicholas DA, Mirfakhraee M, Hayden CK, Amparo EG. Developmental features of the neonatal brain: MR imaging. Gray-white matter differentiation and myelination. Radiology 1987; 162:223–229.
Counsell SJ, Maalouf EF, Fletcher AM, Duggan P, Battin M, Lewis HJ, Herlihy AH, Edwards AD, Bydder GM, Rutherford MA. MR imaging assessment of myelination in the very preterm brain. AJNR Am J Neuroradiol 2002; 23:872–881.
Barkovich AJ: MR of the normal neonatal brain: assessment of deep structures. AJNR Am J Neuroradiol 1998; 19:1397–1403.
Battin M, Rutherford MA. Magnetic resonance imaging of the brain in preterm infants: 24 weeks’ gestation to term. In: Rutherford MA (ed) MRI of the neonatal brain. Edinburgh: WB Saunders, 2002:25–49.
Curnes JT, Burger PC, Djang WT, Boyko OB. MR imaging of compact white matter pathways. AJNR Am J Neuroradiol 1988; 9:1061–1068.
van der Knaap MS, Valk J. Magnetic resonance of myelin, myelination, and myelin disorders, 2nd ed. Berlin: Springer, 1995:31–52.
Bird CR, Hedberg M, Drayer BP, Keller PJ, Flom RA, Hodak JA. MR assessment of myelination in infants and children: usefulness of marker sites. AJNR Am J Neuroradiol 1989; 10:731–740.
Neil J, Miller J, Mukherjee P, Huppi PS. Diffusion tensor imaging in normal and injured developing human brain — a technical review. NMR Biomed 2002; 15:543–552.
Neil JJ, Shiran SI, McKinstry RC, Schefft GL, Snyder AZ, Almli CR, Akbudak E, Aronovitz JA, Miller JP, Lee BC, Conturo TE. Normal brain in human newborns: Apparent diffusion coefficient and diffusion anisotropy measured by using diffusion tensor MR imaging. Radiology 1998; 209:57–66.
Neil JJ, Mc Kinstry RC, Shiran SI, Snyder AZ, Conturo TE. Timing of changes on diffusion tensor imaging following brain injury in full-term infants. Ann Neurol 1998; 44:551.
van der Knaap MS, Valk J: MR imaging of the various stages of normal myelination during the first year of life. Neuroradiology 1990; 31:459–470.
Kinney HC, Brody BA, Kloman AS, Gilles FH. Sequence of central nervous system myelination in human infancy. Patterns of myelination in autopsied infants. J Neuropathol Exp Neurol 1988; 47:217–234.
Baierl P, Forster C, Fendel H, Naegele M, Fink U, Kenn W. Magnetic resonance imaging of normal and pathological white matter maturation. Pediatr Radiol 1988; 18:183–189.
Parazzini C, Baldoli C, Scotti G, Triulzi F. Terminal zoneS of myelination: MR evaluation of children aged 20–40 months. AJNR Am J Neuroradiol 2002; 23:1669–1673.
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Parazzini, C., Bianchini, E., Triulzi, F. (2005). Myelination. In: Pediatric Neuroradiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26398-5_2
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DOI: https://doi.org/10.1007/3-540-26398-5_2
Publisher Name: Springer, Berlin, Heidelberg
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