The Sentinel Node Concept in Cancers of the Female Genitalia


Positron Emission Tomography Sentinel Lymph Node Lymphatic Mapping Sentinel Node Mapping Penile Cancer 
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  1. Ansink A, Velden J van der (2000) Surgical interventions for early squamous cell carcinoma of the vulva. Cochrane Database Syst Rev (2): CD 002036Google Scholar
  2. Ansink AC, Daisy MDS, Velden J van der, Sijmons EA, Barros Lopes A de, Monaghan JM, Kenter GG, Murdoch JB, Kate FJW ten, Heintz APM (1999) Identification of sentinel lymph-nodes in vulvar carcinoma patients with the aid of a patent blue V injection. Cancer 86:652–656CrossRefPubMedGoogle Scholar
  3. Barton DPJ, Berman C, Cavanagh D, Roberts WS, Hoffmann MS, Fiorica JV, Finan MA (1992) Lymphoscintigraphy in vulvar cancer. Gynecol Oncol 46:341–344CrossRefPubMedGoogle Scholar
  4. Burke TW, Levenback CH, Tornos C, Morris M, Wharton JT, Gershenson DM (1996) Intraabdominal lymphatic mapping to direct selective pelvic and paraaortic lymphadenectomy in women with high risk endometrial cancer: results of a pilot study. Gynecol Oncol 62:169–173PubMedGoogle Scholar
  5. Cavanagh D (1997) Vulvar cancer: continuing evolution in management. Gynecol Oncol 66:362–367CrossRefPubMedGoogle Scholar
  6. De Cesare SL, Fiorica JV, Roberts WS, Reintgen D, Arango H, Hoffmann MS, Puleo C, Cavanagh D (1997) A pilot study utilizing intraoperative lymphoscintigraphy for identification of the sentinel nodes in vulvar cancer. Gynecol Oncol 66:425–428CrossRefPubMedGoogle Scholar
  7. De Cicco C, Sideri M, Bartolomei M, Grana C, Cremonesi M, Fiorenza M, Maggioni A, Bocciolone L, Mangioni C, Colombo N, Paganelli G (2000) Sentinel node biopsy in early vulvar cancer. Cancer 82:295–299CrossRefPubMedGoogle Scholar
  8. De Hullu JA, Doting E, Piers DA, Hollem H, Aalders JG, Schraffords Koops H, Boonstra J, Zee AGJ van der (1998) Sentinel lymph node identification with technetium-99m-labeled nanocolloid in squamous cell cancer of the vulva. J Nucl Med 39:1381–1385PubMedGoogle Scholar
  9. De Hullu JA, Ansink AC, Tymstra T, Zee AG van der (2001) What doctors and patients think about false negative sentinel lymph-nodes in vulvar cancer. J Psychosom Obstet Gynaecol 22:199–203PubMedGoogle Scholar
  10. Echt ML, Finan MA, Hoffman MS, Kline RC, Roberts WS, Fiorica JV (1999) Detection of sentinel lymph-nodes with lymphazurin in cervical, uterine and vulvar malignancies. Southern Med J 92:204–208Google Scholar
  11. Fenchel S, Kotzerke J, Stohr I, Grab D, Nussle K, Rieber A, Kreienberg R, Brambs HJ, Reske SN (1999) Preoperative assessment of asymptomatic adnexal tumors by positron emission tomography and F-18 fluorodeoxyglucose. Nuklearmedizin 38:101–107PubMedGoogle Scholar
  12. Hacker NF, Leuchter RS, Berek JS, Castaldo TW, Lagasse LD (1981) Radical vulvectomy and bilateral inguinal lymphadenectomy through separate groin incisions. Obstet Gynecol 58:574–579PubMedGoogle Scholar
  13. Horenblas S, Jansen L, Meinhardt W, Hoefnagel CA, De Jong D, Nieweg OE (2000) Detection of occult metastasis in squamous cell carcinoma of the penis using a dynamic sentinel node procedure. J Urol 163:100–104Google Scholar
  14. Hübner KF, McDonald TW, Niethammer JG, Smith GT, Gould HR, Buonocore E (1993) Assessment of primary and metastatic ovarian cancer by positron emission tomography (PET) using 2-[18F]deoxyglucose (2-[18F]FDG). Gynecol Oncol 51:197–204CrossRefPubMedGoogle Scholar
  15. Iversen T, Aas M (1983) Lymph drainage from the vulva. Gynecol Oncol 16:179–189CrossRefPubMedGoogle Scholar
  16. Lantzsch T, Wolters M, Grimm J, Mende T, Buchmann J, Sliutz G, Koelbl H (2001) Sentinel node procedure in Ib cervical cancer: a preliminary series. Br J Cancer 85(6):791–794CrossRefPubMedGoogle Scholar
  17. Levenback C, Burke TW, Morris M, Malpica A, Lucas KR, Gershenson DM (1995) Potential applications of intraoperative lymphatic mapping in vulvar cancer. Gynecol Oncol 59:216CrossRefPubMedGoogle Scholar
  18. Levenback C, Coleman RL, Burke TW, Bodurka-Bevers D, Wolf JK, Gershenson DM (2001) Intraoperative lymphatic mapping and sentinel node identification with blue dye in patients with vulvar cancer. Gynecol Oncol 83(2):276–281CrossRefPubMedGoogle Scholar
  19. Levenback C, Coleman RL, Burke TW, Lin WM, Erdman W, Deavers M, Delpassand ES (2002) Lymphatic mapping and sentinel node identification in patients with cervix cancer undergoing radical hysterectomy and pelvic lymphadenectomy. J Clin Oncol 20:688–693CrossRefPubMedGoogle Scholar
  20. Makar AP, Scheistroen M, Weyngaert D van den, Trope CG (2001) Surgical management of stage I and II vulvar cancer. The role of the sentinel node biopsy. Review of literature. Int J Gynecol Cancer 11(4):255–262CrossRefPubMedGoogle Scholar
  21. Molpus KL, Kelley MC, Johnson JE, Martin WH, Jones HW 3rd (2001) Sentinel lymph node detection and microstaging in vulvar carcinoma. J Reprod Med 46(10):863–869PubMedGoogle Scholar
  22. Podratz KC, Symmonds RE, Taylor F (1982) Carcinoma of the vulva: analysis of treatment failures. Am J Obstet Gynecol 143:340–351PubMedGoogle Scholar
  23. Ramirez PT, Levenback C (2001) Sentinel nodes in gynecologic malignancies. Curr Opin Oncol 13:403–407CrossRefPubMedGoogle Scholar
  24. Römer W, Avril N, Dose J, Ziegler S, Kuhn W, Herz M, Jänicke F, Schwaiger M (1997) Metabolic characterization of ovarian tumors with positron-emission tomography and F-18 fluorodeoxyglucose. Röfo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 166:62–68PubMedGoogle Scholar
  25. Schröder W, Zimny M, Rudlowski C, Bull U, Rath W (1999) The role of 18F-fluoro-deoxyglucose positron emission tomography (18F-FDG PET) in diagnosis of ovarian cancer. Int J Gynecol Cancer 9:117–122CrossRefPubMedGoogle Scholar
  26. Sliutz G, Reinthaller A, Lantzsch T, Mende T, Sinzinger H, Kains C, Koelbl H (2002) Lymphatic mapping of sentinel nodes in early vulvar cancer. Gynecol Oncol 84:449–452CrossRefPubMedGoogle Scholar
  27. Tavares MG, Sapienza MT, Galeb NA Jr, Belfort FA, Costa RR, Osorio CA, Goes JC, Endo IS, Soares J Jr, Lewin S, Marone MM (2001) The use of 99mTc-phytate for sentinel node mapping in melanoma, breast cancer and vulvar cancer: a study of 100 cases. Eur J Nucl Med 28:1597–1604CrossRefPubMedGoogle Scholar
  28. Terada KY, Coel MN, Ko P, Wong JH (1998) Combined use of intraoperative lymphatic mapping and lymphoscintigraphy in the management of squamous cell cancer of the vulva. Gynecol Oncol 70:65–69CrossRefPubMedGoogle Scholar
  29. Terada KY, Shimizu DM, Wong JH (2000) Sentinel node dissection and ultrastaging in squamous cell cancer of the vulva. Gynecol Oncol 76:40–44CrossRefPubMedGoogle Scholar
  30. Verheijen RH, Pijpers R, Diest PJ van, Burger CW, Buist MR, Kenemans P (2000) Sentinel node detection in cervical cancer. Obstet Gynecol 96(1):135–138CrossRefPubMedGoogle Scholar
  31. Wawroschek F, Vogt H, Weckermann D, Wagner T, Harzmann R (1999) The sentinel lymph node concept in prostate cancer — first results of gamma probe guided sentinel lymph node identification. Eur Urol 36:595–600CrossRefPubMedGoogle Scholar
  32. Wawroschek F, Vogt H, Bachter D, Weckermann D, Hamm M, Harzmann R (2000) First experience of gamma probe guided sentinel lymph node surgery in penile cancer. Urol Res 28:246–249CrossRefPubMedGoogle Scholar
  33. Wawroschek F, Vogt H, Weckermann D, Wagner T, Hamm M, Harzmann R (2001) Radioisotope guided pelvic lymph node dissection of prostate cancer. J Urol 166(5):1715–1719CrossRefPubMedGoogle Scholar

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