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Synthesis and investigation of collagen model peptides

  • Eckhart Heidemann
  • Werner Roth
Conference paper
Part of the Advances in Polymer Science book series (POLYMER, volume 43)

Abstract

So far, model peptides have been synthesized mainly by the liquid- or solid-phase technique in which tripeptides with negligible degree of racemization are coupled in a stepwise manner with polypeptides with defined chain lengths. Through cross bridging of such chains, triple helical models can be obtained containing 15–30 tripeptides which fold and unfold quickly and reversibly. This paper reviews the present state of knowledge in this area and discusses some consequences for the collagen structure based on experimental findings.

Keywords

Circular Dichroism Circular Dichroism Spectrum Triple Helix Transition Curve Model Peptide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1982

Authors and Affiliations

  • Eckhart Heidemann
    • 1
  • Werner Roth
    • 1
  1. 1.Fachgebiet Makromolekulare Chemie, Abteilung Eiweiß und LederTechnische Hochschule DarmstadtDarmstadtFederal Republic of Germany

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