Indication for Antireflux Surgery

  • K. -H. Fuchs
  • M. Fein
  • J. Maroske
  • W. Breithaupt
  • I. Hammer


Lower Esophageal Sphincter Antireflux Surgery Esophageal Acid Exposure Anterior Fundoplication Endoscopic Argon Plasma Coagulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. [1]
    Patterson EJ, Herron DM, Hansen PD, Ramzi N, Standage BA, Swanstrom LL (2000) Effect of an esophageal bougie on the incidence of dysphagia following nissen fundoplication; a prospective, blinded, randomized clinical trial. Arch Surg 135(9): 1055–1061; Discussion 1061–1062PubMedCrossRefGoogle Scholar
  2. [2]
    Peillon C, Manouvrier JL, Labreche J, Kaeffer N, Testart DP (1994) Should be vagus nerves be isolated from the fundoplication wrap? A prospective study. Arch Surg 129(8): 814–818PubMedGoogle Scholar
  3. [3]
    Watson DI, Pike GK, Baigrie RJ, Mathew G, Devitt PG, Britten-Jones R, Jamieson GG (1997) Prospective double-blind randomized trial of laparoscopic Nissen fundoplication with division and without division of short gastric vessels. Ann Surg 226(5): 642–652PubMedCrossRefGoogle Scholar
  4. [4]
    Patterson EJ, Herron DM, Hansen PD, Ramzi N, Standage BA, Swanstrom LL (2000) Effect of an esophageal bougie on the incidence of dysphagia following nissen fundoplication; a prospective, blinded, randomized clinical trial. Arch Surg 135(9): 1055–1061; Discussion 1061–1062PubMedCrossRefGoogle Scholar
  5. [5]
    Zornig C, Strate U, Fibbe C, Emmermann A, Layer P (2002) Nissen vs Toupet laparoscopic fundoplication. Surg Endosc 16(5): 758–766PubMedCrossRefGoogle Scholar
  6. [6]
    Jamieson GG, Watson DI, Britten-Jones R, Mitchell PC, Anvari M (1994) Laparoscopic Nissen fundoplication. Ann Surg 220: 137–145PubMedGoogle Scholar
  7. [7]
    Dallemagne B, Weerts JM, Jehaes C, Markiewicz S (1996) Causes of failures of laparoscopic antireflux operations. Surg Endosc 10: 305–310PubMedCrossRefGoogle Scholar
  8. [8]
    Perdikis G, Hinder RA, Lund RJ, Raiser F, Katada N (1997) Laparoscopic Nissen fundoplication: Where do we stand? Surg Laparoscopy Endoscopy 7: 117–121Google Scholar
  9. [9]
    Hüttl TP, Hohle M, Meyer G, Schildberg FW (2002) Antirefluxchirurgie in Deutschland. Chirurg 73(5): 451–461PubMedCrossRefGoogle Scholar
  10. [10]
    Vigneri S, Termini R, Leandro G, Badalamenti S, Pantalena M, Savarino V, Di Mario F, Battaglia G, Mela GS, Pilotto A (1995) A comparison of five maintenance therapies for reflux esophagitis. N Engl J Med 326: 1106–1110CrossRefGoogle Scholar
  11. [11]
    Klinkenberg-Knol EC, Nelis F, Dent J et al (2000) Long-term Omeprazole treatment in resistant gastroesophageal reflux disease: efficacy, safety, and influence on gastric mucosa. Gastroenterology 118: 661–669PubMedCrossRefGoogle Scholar
  12. [12]
    Eypasch E, Neugebauer E, Fischer F, Troidl H (1997) Laparoscopic antireflux surgery for gastroesophageal reflux disease (GERD). Results of a consensus development conference. Surg Endoscopy 11: 413–426CrossRefGoogle Scholar
  13. [13]
    Fuchs KH, Feussner H, Bonavina L, Collard JM, Coosemans W for the European Study Group for Antireflux Surgery (1997) Current status and trends in laparoscopic antireflux surgery: results of a consensus meeting. Endoscopy 29: 298–308PubMedCrossRefGoogle Scholar
  14. [14]
    Dent J, Brun J, Fendrick AM, Fennerry MB, Janssens J et al (1999) Genval Workshop Group: An evidence-based appraisal of reflux disease management. Gut 44: S1–S16CrossRefGoogle Scholar
  15. [15]
    DeMeester TR, Johnson LF, Kent AH (1974) Evaluation of current operations for the prevention of gastroesophageal reflux. Ann Surg 180: 511–525PubMedGoogle Scholar
  16. [16]
    Fuchs KH, Freys SM, Heimbucher J, Fein M, Thiede A (1995) Pathophysiologic spectrum in patients with gastroesophageal reflux disease in a surgical GI function laboratory. Diseases of the Esophagus 8: 211–217Google Scholar
  17. [17]
    DeMeester TR, Johnson LS, Joseph GJ, Toscano MS, Hall AW, Skinner DB (1976) Patterns of gastroesophageal reflux in health and disease. Ann Surg 184: 459–470PubMedGoogle Scholar
  18. [18]
    Vaezi MF, Richter JE (1995) Synergism of acid and duodeno-gastro-esophageal reflux in complicated Barrett’s esophagus. Surgery 117: 699–704PubMedGoogle Scholar
  19. [19]
    Fein M, Ireland AP, Ritter MP, Peters JH, Hagen JA, Bremner CG, DeMeester TR (1997) Duodenogastric reflux potentiates the injurious effects of gastroesophageal reflux. J Gastrointest Surg 1: 27–33PubMedCrossRefGoogle Scholar
  20. [20]
    Behar J, Sheahan DG, Biancani P, Spiro HM, Storer EH (1975) Medical and surgical management of reflux esophagitis. New Engl J Med: 263–268Google Scholar
  21. [21]
    Stuart RC, Dawson K, Keeling P, Byrne PJ, Hennessy TP (1989) A prospective randomized trial of Angelchik prosthesis versus Nissen fundoplication. Br J Surg 76: 86–89PubMedGoogle Scholar
  22. [22]
    Thor KBA, Silander T (1989) A long-term randomized prospective trial of the Nissen procedure versus a modified Toupet technique. Ann Surg 210: 719–724PubMedGoogle Scholar
  23. [23]
    Kmiot WA, Kirby RM, Akinola D, Temple JG (1991) Prospective randomized trial of Nissen fundoplication and Angelchik prosthesis in the surgical treatment of medically refractory gastro-oesophageal reflux disease. Br J Surg 78: 1181–1184PubMedGoogle Scholar
  24. [24]
    Lundell L, Abrahamsson H, Ruth M, Sandberg L, Olbe L (1991) Lower esophageal sphincter characteristics and esophageal acid exposure following partial or 360° fundoplication: Results of a prospective, randomized, clinical study. World J Surg 15: 115–121PubMedCrossRefGoogle Scholar
  25. [25]
    Spechler SJ and the department of veterans affairs gastroesophageal reflux disease study group (1992) Comparison of medical and surgical therapy for complicated gastroesophageal reflux disease in veterans. N Engl J Med 326,12: 786–792PubMedCrossRefGoogle Scholar
  26. [26]
    Eyre-Brook IA, Codling BW, Gear MWL (1993) Results of a prospective randomized trial of the Angelchik prosthesis and of a consecutive series of 119 patients. Br J Surg 80: 602–604PubMedGoogle Scholar
  27. [27]
    Janssen IMC, Gouma DJ, Klementschitsch P, van der Heyde MN, Obertop H (1993) Prospective randomized comparison of teres cardiopexy and Nissen fundoplication in the surgical therapy of gastro-oesophageal reflux disease. Br J Surg 80: 875–878PubMedGoogle Scholar
  28. [28]
    Hill ADK, Walsh TN, Bolger CM, Byrne PJ, Hennessy TPJ (1994) Randomized controlled trial comparing Nissen fundoplication and the Angelchik prosthesis. Br J Surg 81: 72–74PubMedGoogle Scholar
  29. [29]
    Ortiz EA, Martinez de Haro LF, Parrilla P, Morales G, Molina J, Bermejo J, Liron R, Aguilar J (1996) Conservative treatment versus antireflux surgery in Barrett’s oesophagus: long-term results of a prospective study. Br J Surg 83(2): 274–278PubMedCrossRefGoogle Scholar
  30. [30]
    Lundell L, Abrahamsson H, Ruth M, Rydberg L, Lonroth H, Olbe L (1996) Long-term results of a prospective randomized comparison of total fundic wrap (Nissen-Rossetti) or semifundoplication (Toupet) for gastro-oesophageal reflux. Br J Surg 83(6): 830–835PubMedGoogle Scholar
  31. [31]
    Rydberg L, Ruth M, Lundell L (1997) Does oesophageal motor function improve with time after successful antireflux surgery? Results of a prospective, randomized clinical study. Gut 41: 82–86PubMedCrossRefGoogle Scholar
  32. [32]
    Watson DI, Pike GK, Baigrie RJ, Mathew G, Devitt PG, Britten-Jones R, Jamieson GG (1997) Prospective double-blind randomized trial of laparoscopic Nissen fundoplication with division and without division of short gastric vessels. Ann Surg 226(5): 642–652PubMedCrossRefGoogle Scholar
  33. [33]
    Laws HL, Clements RH, Swillie CM (1997) A randomized, prospective comparison of the Nissen fundoplication versus the Toupet fundoplication for gastroesophageal reflux disease. Ann Surg 225(6): 647–653; Discussion 654PubMedCrossRefGoogle Scholar
  34. [34]
    Anderson JA, Myers JC, Watson DI, Gabb M, Mathew G, Jamieson GG (1998) Concurrent fluoroscopy and manometry reveal differences in laparoscopic Nissen and anterior fundoplication. Dig Dis Sci 43(4): 847–853PubMedCrossRefGoogle Scholar
  35. [35]
    Lundell L, Dalenbäck J, Hattlebakk J et al (1998) Outcome of open antireflux surgery as assessed in a nordic multicentre, prospective clinical trial. Eur J Surg 164: 751–757PubMedCrossRefGoogle Scholar
  36. [36]
    Rydberg L, Ruth M, Abrahamsson H, Lundell L (1999) Tailoring antireflux surgery: a randomized clinical trial. World J Surg 23: 612–618PubMedCrossRefGoogle Scholar
  37. [37]
    Watson DI, Jamieson GG, Pike GK, Davies N, Richardson M, Devitt PG (1999) Prospective randomized double-blind trial between laparoscopic Nissen fundoplication and anterior partial fundoplication. Br J Surg 86: 123–130PubMedCrossRefGoogle Scholar
  38. [38]
    Luostarinen MES, Isolauri JO (1999) Randomized trial to study the effect of fundic mobilization on long-term results of Nissen fundoplication. Br J Surg 86: 614–618PubMedCrossRefGoogle Scholar
  39. [39]
    Csendes A, Burdiles P, Korn O, Braghetto I, Huertas C, Rojas J (2000) Late results of a randomized clinical trial comparing total fundoplication versus calibration of the cardia with posterior gastropexy. Br J Surg 87: 289–297PubMedCrossRefGoogle Scholar
  40. [40]
    Bais JE, Bartelsman JF, Bonjer HJ, Cuesta MA, Go PM, Klinkenberg-Knol EC, van Lanschot JJB, Nadorp JH, Smout AJ, van der Graaf Y (The Netherlands Antireflux Surgery Study Group) (2000) Laparoscopic or conventional Nissen fundoplication for gastroesophageal reflux disease: randomized clinical trial. Lancet 355: 170–174PubMedCrossRefGoogle Scholar
  41. [41]
    Nilsson G, Larsson S, Johnsson F (2000) Randomized clinical trial of laparoscopic versus open fundoplication: blind evaluation of recovery and discharge period. Br J Surg 87: 873–878PubMedCrossRefGoogle Scholar
  42. [42]
    Lundell L, Miettinen P, Myrvold HE, Pedersen SA, Liedman B, Hatlebakk JG, Julkonen R, Levander K, Carlsson J, Lamm M, Wiklund I (2001) Continued (5-year) followup of a randomized clinical study comparing antireflux surgery and omeprazole in gastroesophageal reflux disease. J Am Coll Surg 192(2): 172–179; Discussion 179–181PubMedCrossRefGoogle Scholar
  43. [43]
    Luostarinen M, Virtanen J, Koskinen M, Matikainen M, Isolauri J (2001) Dysphagia and oesophageal clearance after laparoscopic versus open Nissen fundoplication. A randomized, prospective trial. Scand J Gastroenterol 6: 565–571CrossRefGoogle Scholar
  44. [44]
    Spechler SJ, Lee E, Ahnen D, Goyal RK, Hirano I, Williford WO (2001) Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease. JAMA 285: 2331–2338PubMedCrossRefGoogle Scholar
  45. [45]
    Costantini M, Crookes PF, Bremner RM, Hoeft SF, Ehsan A, Peters JH, Bremner CG, DeMeester TR (1993) Value of physiologic assessment of foregut symptoms in a surgical practice. Surgery 114(4): 780–786PubMedGoogle Scholar
  46. [46]
    Campos GM, Peters JH, DeMeester TR, Oberg S, Crookes PF, Tan S, DeMeester SR, Hagen JA, Bremner CG (1999) Multivariate analysis of factors predicting outcome after laparoscopic Nissen fundoplication. J Gastrointest Surg 3(3): 292–300PubMedCrossRefGoogle Scholar
  47. [47]
    Peters JH, DeMeester TR, Crookes P, Oberg S, de Vos Shoop M, Hagen JA, Bremner CG (1998) The treatment of gastroesophageal reflux disease with laparoscopic Nissen Fundoplication. Ann Surg 228(1): 40–50PubMedCrossRefGoogle Scholar
  48. [48]
    Kuster E, Ros E, Toledo-Pimentel V, Pujol A, Bordas JM, Grande IC (1994) Predictive factors of the long term outcome in gastro-oesophageal reflux disease: six year follow up of 107 patients. Gut 35(1): 8–14PubMedGoogle Scholar
  49. [49]
    Blom D, Peters JH, DeMeester TR, Crookes P, Hagen JA, DeMeester SR, Bremner CG (2002) Physiologic mechanism and preoperative prediction of new-onset dysphagia after laparoscopic Nissen fundoplication. J Gastrointest Surg 6(1): 22–27PubMedCrossRefGoogle Scholar
  50. [50]
    Fang J, Bjorkman D (2002) Prefundoplication testing: is manometry needed? Am J Gastroenterol 97(4): 1056–1058PubMedGoogle Scholar
  51. [51]
    Fibbe C, Layer P, Keller J et al (2001) Esophageal motility in reflux disease before and after fundoplication: a prospective, randomized, clinical and manometric study. Gastroenterology 121: 5–14PubMedCrossRefGoogle Scholar
  52. [52]
    Haggit RC, Tryzelaar J, Ellis FH, Colcher H (1978) Adenocarcinoma complicating columnar-epithelium-lined (Barrett’s) esophagus. Am J Clin Pathol 70: 1Google Scholar
  53. [53]
    Hameeteman W, Tytgat GNJ, Houthoff HJ, Van Den Tweel JG (1989) Barrett’s esophagus: development of dysplasia and adenocarcinoma. Gastroenterology 96: 1249–1256PubMedGoogle Scholar
  54. [54]
    Pera M, Cameron AJ, Trastek VF, Carpenter HA, Zinsmeister AR (1993) Increasing incidence of adenocarcinoma of the esophagus and esophagogastric junction. Gastroenterology 104: 510–513PubMedGoogle Scholar
  55. [55]
    Lagergren J, Bergström R, Lindgren A, Nyrén O (1999) Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. The New England J of Medicine 340: 825–831CrossRefGoogle Scholar
  56. [56]
    DeMeester SR, DeMeester TR (2000) Columnar mucosa and intestinal metaplasia of the esophagus: fifty year controversy. Ann Surg 231(2): 303–321PubMedCrossRefGoogle Scholar
  57. [57]
    Corey KE, Schmitz SM, Shaheen NJ (2003) Does a surgical antireflux procedure decrease the incidence of esophageal adenocarcinoma in Barrett’s esophagus? A meta-analysis. Am J Gastroenterol 98(11): 2390–2394PubMedCrossRefGoogle Scholar
  58. [58]
    Tigges H, Fuchs KH, Maroske J, Fein M, Freys SM, Muller J, Theide A (2001) Combination of endoscopic argon plasma coagulation and antireflux surgery for treatment of Barrett’s esophagus. J Gastrointest Surg 5(4): 251–259PubMedCrossRefGoogle Scholar
  59. [59]
    Laine S, Rantala A, Gullichsen R, Ovaska J (1997) Laparoscopic vs conventional Nissen fundoplication. A prospective randomized study. Surg Endosc 11: 441–444PubMedCrossRefGoogle Scholar
  60. [60]
    Heikkinen TJ, Hakipuro K, Bringman S (2000) Comparison of laparoscopic and open Nissen fundoplication 2 years after operation. A prospective randomized trial. Surg Endosc 355: 170–174Google Scholar
  61. [61]
    Chrysos E, Tsiaoussis J, Athanasakis E, Vassilakis J, Xynos E (2002) Laparoscopic versus open approach for Nissen fundoplication. Surg Endosc 16: 1679–1684PubMedCrossRefGoogle Scholar
  62. [62]
    Stein HJ, Barlow AP, DeMeester TR, Hinder RA (1992) Complications of gastroesophageal reflux disease. Role of the lower esophageal sphincter, esophageal acid and acid/alkaline exposure, and duodenogastric reflux. Ann Surg 216(1): 35–43PubMedGoogle Scholar
  63. [63]
    Fein M, Ritter MP, DeMeester TR, Oberg S, Peters JH, Hagen JA, Bremner CG (1999) Role of the lower esophageal sphincter and hiatal hernia in the pathogenesis of gastroesophageal reflux disease. J Gastrointest Surg 3(4): 405–410PubMedCrossRefGoogle Scholar
  64. [64]
    Jones MS, Sloan SS, Rabine JC, Ebert CC, Huang CF, Kahrilas PJ (2001) Hiatal hernia size is the dominant determinant of esophagitis presence and severity in gastroesophageal reflux disease. Am J Gastroenterol 96(6): 1711–1717PubMedCrossRefGoogle Scholar
  65. [65]
    Flum DR, Koepsell T, Heagerty P, Pellegrini CA (2002) The nationwide frequency of major adverse outcomes in antireflux surgery and the role of surgeon experience, 1992–1997. J Am Coll Surg 195(5): 611–618PubMedCrossRefGoogle Scholar
  66. [66]
    Heudebert GR, Marks R, Wilcox CM et al (1997) Choice of long-term strategy for the management of patients with severe esophagitis: a cost-utility analysis. Gastroenterology 112: 1078–1086PubMedCrossRefGoogle Scholar
  67. [67]
    Fuchs KH, Tigges H, Heimbucher J et al (1997) Laparoskopische Eingriffe bei gastroösophagealer Refluxkrankheit — eine Nutzen-Kosten-Analyse. Zentralbl Chir 122: 1072–1077PubMedGoogle Scholar
  68. [68]
    Myrvold HE, Lundell L Nordic GERD Study Group (2001) The cost of long-term therapy for gastroesophageal reflux disease: a randomized trial comparing omeprazole and open antireflux surgery. Gut 49(4): 462–463CrossRefGoogle Scholar

Copyright information

© Springer-Verlag/Wien 2006

Authors and Affiliations

  • K. -H. Fuchs
    • 1
  • M. Fein
    • 2
  • J. Maroske
    • 2
  • W. Breithaupt
    • 1
  • I. Hammer
    • 1
  1. 1.Department of Surgery, Markus-KrankenhausFrankfurter Diakonie-KlinikenFrankfurt am MainGermany
  2. 2.Department of SurgeryUniversity of WürzburgWürzburgGermany

Personalised recommendations