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New Concepts for Organocatalysis

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Organocatalysis

Part of the book series: Ernst Schering Foundation Symposium Proceedings ((SCHERING FOUND,volume 2007/2))

Abstract

Organocatalysis, catalysis with low-molecular weight catalysts in which a metal is not part of the catalytic principle or the reaction substrate, can be as efficient and selective as metal- or biocatalysis. Important discoveries in this area include novel Lewis base-catalyzed enantioselective processes and, more recently, simple Brønsted acid organocatalysts that rival the efficiency of traditional metal-based asymmetric Lewis acid-catalysts. Contributions to organocatalysis from our laboratories include several new and broadly useful concepts such as enamine catalysis and asymmetric counteranion-directed catalysis. Our laboratory has discovered the proline-catalyzed direct asymmetric intermolecular aldol reaction and introduced several other organocatalytic reactions.

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Acknowledgements

The present and past co-workers in my laboratory, whose names are given in the list of references, are highly acknowledged for their hard work, skill and enthusiasm. I thank the National Institute of Health for funding my work at Scripps. Generous support by the Max-Planck-Society and by Novartis (Young Investigator Award to BL) is gratefully acknowledged. I also thank the DFG (Priority Program Organocatalysis SPP1179), Degussa, Wacker, Merck, Saltigo, Sanofi-Aventis and BASF for general support and donating chemicals. I also thank Professor Kendall. N. Houk and Professor Walter Thiel for fruitful collaborations.

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  1. Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470, Mülheim an der Ruhr, Germany

    S. C. Pan & B. List

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  1. S. C. Pan
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  2. B. List
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Correspondence to B. List .

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M.T. Reetz B. List S. Jaroch H. Weinmann

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Pan, S.C., List, B. (2008). New Concepts for Organocatalysis. In: Reetz, M., List, B., Jaroch, S., Weinmann, H. (eds) Organocatalysis. Ernst Schering Foundation Symposium Proceedings, vol 2007/2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/2789_2008_084

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