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Benign Tumors/Premalignant Conditions

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Radiation Therapy of Benign Diseases

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Adamantinoma is a locally aggressive low-grade bone tumor that is histologically similar to ameloblastoma (sometimes also called “jaw adamantinoma”) (Van Rijn et al. 2006). The median patient age at diagnosis is 30 years (Jain et al. 2008). The tumor typically occurs in the long bones, with a predominance for the midportion of the tibia (85% of cases) but can also sometimes involve the fibula (Keeney et al. 1989; Baker et al. 1954), humerus (Huvos and Marcove 1975), ulna (Sherman et al. 2003), femur (Makhson et al. 2006), radius (Bourne et al. 1988), innominate bones (Lasda and Hughes Jr. 1979), ribs (Beppu et al. 1994), spine (Dini et al. 2006), and rarely bones of the hand and foot (Diepeveen et al. 1960). Patients typically present with an indolent growth over several years causing swelling with or without pain. Involvement of the anterior tibia can lead to a bowing deformity of the tibia, and up to 1 in 4 patients presents with a pathological fracture (Qureshi et al. 2000). The metastasis rate is reported to be around 10–20%, most commonly for the lungs (Jain et al. 2008; Nouri et al. 2011; Papagelopoulos et al. 2007).

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    Houda Bahig & David Roberge

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Bahig, H., Roberge, D. (2023). Benign Tumors/Premalignant Conditions. In: Roberge, D., Donaldson, S.S. (eds) Radiation Therapy of Benign Diseases. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2022_366

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