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Tumor Motion Control

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Advances in Radiation Oncology in Lung Cancer

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

Lung tumors in the thorax move by respiration during radiotherapy. Four-dimensional computed tomography (4DCT) and patient-dependent determination of margins for tumor motion are strongly recommended in the treatment planning of high-dose external beam therapy, such as stereotactic body radiotherapy (SBRT) for lung cancers. As tumor motion control maneuvers, relaxed steady breathing, a stereotactic body frame and compression plate, deep inspiration breath holding, and active breathing control have been introduced. Meanwhile, it has become obvious that the respiratory motion of lung tumors is different in different patients, on different days, and at different times in the same patient. To accommodate this, daily online imaging and soft tissue setup are now recommended. Three-dimensional image-guided radiotherapy (3D IGRT) is increasingly used with or without internal fiducial markers. Broader application of the 3D IGRT as the minimum requirement is proposed to replace 2D IGRT by experts. Adaptive external beam radiotherapy systems (AEBRS) for intrafractionally moving target volumes, such as beam gating and beam tracking, have been developed to improve the reproducibility of tumor motion control. The superiority of 4DCT planning in clinical outcomes has been suggested in a randomized trial of SBRT for early-stage lung cancer.

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Authors and Affiliations

  1. Faculty of Medicine, Hokkaido University, Sapporo, Japan

    Hiroki Shirato

  2. Faculty of Medicine, Osaka University, Osaka, Japan

    Shinichi Shimizu

  3. Hokkaido University Hospital, Sapporo, Japan

    Hiroshi Taguchi

  4. Faculty of Engineering, Hokkaido University, Sapporo, Japan

    Seishin Takao, Naoki Miyamoto & Taeko Matsuura

Authors
  1. Hiroki Shirato
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  2. Shinichi Shimizu
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  3. Hiroshi Taguchi
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  4. Seishin Takao
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  5. Naoki Miyamoto
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  6. Taeko Matsuura
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Correspondence to Hiroki Shirato .

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  1. School of Medicine, University of Kragujevac, Kragujevac, Serbia

    Branislav Jeremić

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Shirato, H., Shimizu, S., Taguchi, H., Takao, S., Miyamoto, N., Matsuura, T. (2022). Tumor Motion Control. In: Jeremić, B. (eds) Advances in Radiation Oncology in Lung Cancer. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2022_348

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  • DOI: https://doi.org/10.1007/174_2022_348

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-34846-4

  • Online ISBN: 978-3-031-34847-1

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