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Image-Guided Radiotherapy in Lung Cancer

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Advances in Radiation Oncology in Lung Cancer

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

The technological advances in radiation therapy over the last several decades have dramatically improved outcomes for lung cancer patients treated with radiation. In the era of two-dimensional (2D) radiation therapy, poor imaging quality during planning and treatment necessitated inclusion of a large volume of normal tissue in the treatment fields and long treatment courses delivering small doses of radiation therapy daily even for early-stage cancer. As a result, dose was limited due to toxicity, and tumor control was suboptimal. Three-dimensional (3D) conformal radiotherapy incrementally improved outcomes due to better tumor and organ spatial delineation but was still unable to account for real-time tumor motion. The advent of four-dimensional (4D) CT planning addressed this limitation by permitting the characterization of individualized tumor motion during the respiratory cycle. Further advancements in functional and anatomical imaging, precision of radiation delivery devices, and sophisticated onboard image guidance have made it possible to deliver modern-day hypofractionated radiation therapy or stereotactic body radiation therapy (SBRT) for thoracic cancers.

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Authors and Affiliations

  1. Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

    Julius Weng & Percy Lee

  2. Varian Medical Systems, Inc., Palo Alto, CA, USA

    Patrick Kupelian

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  1. Julius Weng
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  2. Patrick Kupelian
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  3. Percy Lee
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Correspondence to Percy Lee .

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Editors and Affiliations

  1. School of Medicine, University of Kragujevac, Kragujevac, Serbia

    Branislav Jeremić

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Weng, J., Kupelian, P., Lee, P. (2022). Image-Guided Radiotherapy in Lung Cancer. In: Jeremić, B. (eds) Advances in Radiation Oncology in Lung Cancer. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2022_345

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  • DOI: https://doi.org/10.1007/174_2022_345

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-34846-4

  • Online ISBN: 978-3-031-34847-1

  • eBook Packages: MedicineMedicine (R0)

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