Management of Incidental Findings on Neuroimaging in the Rotterdam Study
This chapter gives an overview of the management of incidental findings on neuroimaging in the population-based Rotterdam Study, in which brain MRI was introduced as part of the core study protocol in 2005 (1.5 T). To this purpose, a protocol for the management of incidental findings was defined by a group of experts from different fields. During the study, all brain scans are reviewed for incidental findings by group of trained researchers, under the supervision of a neuroradiologist. Only findings deemed of potential clinical relevance (according to the study protocol) are reported to the participants. Overall, incidental findings that require additional clinical review by a medical specialist, of which meningiomas and aneurysms are most common, occur in just over 3%. The vast majority of these undergo a watch and wait policy, indicating that clinical consequences are in most cases limited.
KeywordsIncidental Finding Brain Magnetic Resonance Imaging Rotterdam Study Cerebral Small Vessel Disease Cerebral Microbleeds
- Bos D, Poels MMF, Adams HHH, Akoudad S, et al (2016) Prevalence, clinical management and natural course of incidental findings on brain MRI: A population-based imaging study. Radiol. In pressGoogle Scholar
- Prince M, Bryce R, Albanese E et al (2013) The global prevalence of dementia: a systematic review and metaanalysis. Alzheimers Dement 9(63–75):e62Google Scholar