Future Methods in Tumor Imaging

  • Ulrich Pilatus
  • Elke Hattingen
Part of the Medical Radiology book series (MEDRAD)


Chapter  Advanced MR Methods in Differential Diagnosis of Brain Tumors deals with advanced and future MR imaging methods in brain tumors. In this chapter, we will discuss future MR spectroscopic methods that are promising regarding the tumor diagnosis and the research of tumor biology. Whereas Chap.  MR Spectroscopic Imaging focuses on diagnostic significance of 1H and 31P MRS, we herein put more emphasis on methodical issues of MRS. First, we deal with special editing methods to detect special “tumor” metabolites (glycine, 2-hydroxyglutarate). In the second part, we discuss methods and biological implications of x-nucleus spectroscopy, focusing on the nuclei 31P and 13C. Here, we point out that a considerable proportion of advanced spectroscopic studies dealing with brain tumors come from animal studies.


Dynamic Nuclear Polarization Glutamate Label MRSI Data Lower Gyromagnetic Ratio Lactate Label 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.





Adenosine triphosphate












Inorganic phosphate

TCA cycle

Tricarboxylic acid cycle or Krebs cycle


Total choline


Total creatine


Total N-acetylaspartate


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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Department of NeuroradiologyGoethe University FrankfurtFrankfurtGermany
  2. 2.NeuroradiologyClinic of Rheinische Friedrich-Wilhelms-UniversityBonnGermany

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