Stereotactic Ablative Body Radiation (SABR) and Postoperative Radiation in Non-Small Cell Lung Cancer (NSCLC)

Part of the Medical Radiology book series (MEDRAD)


Carcinomas of the lung originate from the pulmonary parenchyma or the tracheobronchial tree. The latter consists of the trachea, which subdivides into the main bronchi and lobar bronchi bilaterally.


Planning Target Volume Gross Tumor Volume Volumetric Imaging Internal Target Volume Bronchial Stump 


  1. Chapet O, Kong FM, Quint LE et al (2005) CT-based definition of thoracic lymph node stations: an atlas from the University of Michigan. Int J Radiat Oncol Biol Phys 63:170–178CrossRefGoogle Scholar
  2. Lopez Guerra JL, Gomez DR, Lin SH et al (2013) Risk factors for local and regional recurrence in patients with resected N0-N1 non-small-cell lung cancer, with implications for patient selection for adjuvant radiation therapy. Ann Oncol 24:67–74CrossRefGoogle Scholar
  3. Mountain CF, Dresler CM (1997) Regional lymph node classification for lung cancer staging. Chest 111:1718–1723CrossRefGoogle Scholar
  4. Muirhead R, Featherstone C, Duffton A, Moore K, McNee S (2010) The potential clinical benefit of respiratory gated radiotherapy (RGRT) in non-small cell lung cancer (NSCLC). Radiother Oncol 95(2):172–177CrossRefGoogle Scholar
  5. Mutter RW, Liu F, Abreu A, Yorke E, Jackson A, Rosenzweig KE (2012) Dose-volume parameters predict for the development of chest wall pain after stereotactic body radiation for lung cancer. Int J Radiat Oncol Biol Phys 82:1783–1790CrossRefGoogle Scholar
  6. Osarogiagbon RU, Yu X (2012) Mediastinal lymph node examination and survival in resected early-stage non-small-cell lung cancer in the surveillance, epidemiology, and end results database. J Thorac Oncol 7:1798–1806CrossRefGoogle Scholar
  7. Spoelstra FO, Senan S, Le Pechoux C et al (2010) Variations in target volume definition for postoperative radiotherapy in stage III non-small-cell lung cancer: analysis of an international contouring study. Int J Radiat Oncol Biol Phys 76:1106–1113CrossRefGoogle Scholar
  8. Underberg RW, Lagerwaard FJ, Slotman BJ, Cuijpers JP, Senan S (2005) Benefit of respiration-gated stereotactic radiotherapy for stage I lung cancer: an analysis of 4DCT datasets. Int J Radiat Oncol Biol Phys 62:554–560CrossRefGoogle Scholar
  9. Urban D, Bar J, Solomon B, Ball D (2013) Lymph node ratio may predict the benefit of postoperative radiotherapy in non-small-cell lung cancer. J Thorac Oncol 8:940–946CrossRefGoogle Scholar
  10. Welsh J, Thomas J, Shah D et al (2011) Obesity increases the risk of chest wall pain from thoracic stereotactic body radiation therapy. Int J Radiat Oncol Biol Phys 81:91–96CrossRefGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  1. 1.Division of Radiation OncologyUniversity of Texas MD Anderson Cancer CenterHoustonUSA

Personalised recommendations