Pediatric Sarcoma

  • Arthur K. Liu
  • Arnold C. Paulino
Part of the Medical Radiology book series (MEDRAD)


Pediatric sarcomas are a diverse group of diagnoses. The three most common types that involve radiation therapy for local control are Ewing sarcoma (EWS), rhabdomyosarcoma (RMS), and non-rhabdomyosarcoma soft tissue sarcoma (NRSTS). In this chapter, we will discuss the treatment of EWS and RMS which are predominantly seen in the pediatric and young adult population.


Target Volume Clinical Target Volume Ewing Sarcoma Target Volume Delineation Target Volume Definition 
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Suggested Reading

  1. Donaldson SS (2004) Ewing sarcoma: radiation dose and target volume. Pediatr Blood Cancer 42:471–476CrossRefGoogle Scholar
  2. Donaldson SS, Torrey M, Link MP et al (1998) A multidisciplinary study investigating radiotherapy in Ewing’s sarcoma: end results of POG #8346. Pediatric Oncology Group. Int J Radiat Oncol Biol Phys 42:125–135CrossRefGoogle Scholar
  3. Lin C, Donaldson SS, Meza JL et al (2012) Effect of radiotherapy techniques (IMRT vs. 3DCRT) on outcome in patients with intermediate-risk rhabdomyosarcoma enrolled in COG D9803 – a report from the Children’s Oncology Group. Int J Radiat Oncol Biol Phys 82:1764–1770CrossRefGoogle Scholar
  4. Million L, Anderson J, Breneman J et al (2011) Influence of noncompliance with radiation therapy protocol guidelines and operative bed recurrences for children with rhabdomyosarcoma and microscopic residual disease: a report from the Children’s Oncology Group. Int J Radiat Oncol Biol Phys 80:333–338CrossRefGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Arthur K. Liu
    • 1
  • Arnold C. Paulino
    • 2
  1. 1.Department of Radiation OncologyUniversity of Colorado DenverAuroraUSA
  2. 2.Department of Radiation OncologyMD Anderson Cancer CenterHoustonUSA

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