Three-dimensional conformal radiation therapy (3DCRT) has been the standard technique for hepatocellular carcinoma (HCC). Intensity-modulated radiation therapy (IMRT) may be useful to improve target coverage and for normal organ sparing, especially in the setting of unusually shaped target volumes. More recently, stereotactic body radiation therapy (SBRT) has been increasingly used. Individualized prescription doses are commonly used due to variable liver volume irradiation and proximity to luminal gastrointestinal tissues.
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Bi AH et al (2010) Impact factors for microinvasion in intrahepatic cholangiocarcinoma: a possible system for defining clinical target volume. Int J Radiat Oncol Biol Phys 78:1427–1436CrossRefGoogle Scholar
Cheng JC et al (2000) Local radiotherapy with or without transcatheter arterial chemoembolization for patients with unresectable hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 47:435–442CrossRefGoogle Scholar
Todoroki T et al (2000) Benefits of adjuvant radiotherapy after radical resection of locally advanced main hepatic duct carcinoma. Int J Radiat Oncol Biol Phys 46:581–587CrossRefGoogle Scholar
Tse RV et al (2008) Phase I study of individualized stereotactic radiotherapy for hepatocellular carcinoma and intrahepatic cholangiocarcinoma. J Clin Oncol 26:657–664CrossRefGoogle Scholar
Tsuji T et al (2001) Lymphatic spreading pattern of intrahepatic cholangiocarcinoma. Surgery 129:401–407CrossRefGoogle Scholar
Wang NH et al (2010) Impact factors for microinvasion in patients with hepatocellular carcinoma: possible application to the definition of clinical tumor volume. Int J Radiat Oncol Biol Phys 76:467–476CrossRefGoogle Scholar