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Hepatocellular Carcinoma and Cholangiocarcinoma

  • Jason Chia-Hsien Cheng
  • Chia-Chun Wang
  • Inigo San Miguel
  • Laura A. Dawson
Chapter
Part of the Medical Radiology book series (MEDRAD)

Abstract

Three-dimensional conformal radiation therapy (3DCRT) has been the standard technique for hepatocellular carcinoma (HCC). Intensity-modulated radiation therapy (IMRT) may be useful to improve target coverage and for normal organ sparing, especially in the setting of unusually shaped target volumes. More recently, stereotactic body radiation therapy (SBRT) has been increasingly used. Individualized prescription doses are commonly used due to variable liver volume irradiation and proximity to luminal gastrointestinal tissues.

Keywords

Clinical Target Volume Stereotactic Body Radiation Therapy Gross Tumor Volume Intrahepatic Cholangiocarcinoma Abdominal Compression 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Further Reading

  1. Bi AH et al (2010) Impact factors for microinvasion in intrahepatic cholangiocarcinoma: a possible system for defining clinical target volume. Int J Radiat Oncol Biol Phys 78:1427–1436CrossRefGoogle Scholar
  2. Cheng JC et al (2000) Local radiotherapy with or without transcatheter arterial chemoembolization for patients with unresectable hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 47:435–442CrossRefGoogle Scholar
  3. Todoroki T et al (2000) Benefits of adjuvant radiotherapy after radical resection of locally advanced main hepatic duct carcinoma. Int J Radiat Oncol Biol Phys 46:581–587CrossRefGoogle Scholar
  4. Tse RV et al (2008) Phase I study of individualized stereotactic radiotherapy for hepatocellular carcinoma and intrahepatic cholangiocarcinoma. J Clin Oncol 26:657–664CrossRefGoogle Scholar
  5. Tsuji T et al (2001) Lymphatic spreading pattern of intrahepatic cholangiocarcinoma. Surgery 129:401–407CrossRefGoogle Scholar
  6. Wang NH et al (2010) Impact factors for microinvasion in patients with hepatocellular carcinoma: possible application to the definition of clinical tumor volume. Int J Radiat Oncol Biol Phys 76:467–476CrossRefGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Jason Chia-Hsien Cheng
    • 1
    • 2
  • Chia-Chun Wang
    • 2
  • Inigo San Miguel
    • 3
  • Laura A. Dawson
    • 3
  1. 1.Graduate Institute of OncologyNational Taiwan University College of MedicineTaipeiTaiwan
  2. 2.Division of Radiation Oncology, Department of OncologyNational Taiwan University HospitalTaipeiTaiwan
  3. 3.Department of Radiation Oncology, Princess Margaret Cancer CentreUniversity of TorontoTorontoCanada

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