Locally Advanced Non-Small Cell Lung Cancer and Small Cell Lung Cancer

  • Daniel Gomez
  • Peter Balter
  • Zhongxing Liao
Part of the Medical Radiology book series (MEDRAD)


Carcinomas of the lung originate from the pulmonary parenchyma or the tracheobronchial tree. The latter consists of the trachea, which subdivides into the main bronchi and lobar bronchi bilaterally.


Small Cell Lung Cancer Target Volume Planning Target Volume Respiratory Motion Clinical Target Volume 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Bibliography/Suggested Reading

  1. Borst GR, Sonke JJ, Betgen A, Remeijer P, van Herk M, Lebesque JV (2007) Kilo-voltage cone-beam computed tomography setup measurements for lung cancer patients; first clinical results and comparison with electronic portal-imaging device. Int J Radiat Oncol Biol Phys 68:555–561CrossRefPubMedGoogle Scholar
  2. Bradley J, Thorstad WL, Mutic S et al (2004) Impact of FDG-PET on radiation therapy volume delineation in non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 59:78–86CrossRefPubMedGoogle Scholar
  3. Chen GH, Yao ZF, Fan XW et al (2013) Variation in background intensity affects PET-based gross tumor volume delineation in non-small-cell lung cancer: the need for individualized information. Radiother Oncol 109:71–76CrossRefPubMedGoogle Scholar
  4. De Ruysscher D (2011) PET-CT in radiotherapy for lung cancer. Methods Mol Biol 727:53–58CrossRefPubMedGoogle Scholar
  5. De Ruysscher D, Nestle U, Jeraj R, Macmanus M (2012) PET scans in radiotherapy planning of lung cancer. Lung Cancer 75:141–145CrossRefPubMedGoogle Scholar
  6. Giraud P, Antoine M, Larrouy A et al (2000) Evaluation of microscopic tumor extension in non-small-cell lung cancer for three-dimensional conformal radiotherapy planning. Int J Radiat Oncol Biol Phys 48:1015–1024CrossRefPubMedGoogle Scholar
  7. Liao ZX, Komaki RR, Thames HD Jr et al (2010) Influence of technologic advances on outcomes in patients with unresectable, locally advanced non-small-cell lung cancer receiving concomitant chemoradiotherapy. Int J Radiat Oncol Biol Phys 76:775–781CrossRefPubMedGoogle Scholar
  8. Mountain CF, Dresler CM (1997) Regional lymph node classification for lung cancer staging. Chest 111:1718–1723CrossRefPubMedGoogle Scholar
  9. Muirhead R, Featherstone C, Duffton A, Moore K, McNee S (2010) The potential clinical benefit of respiratory gated radiotherapy (RGRT) in non-small cell lung cancer (NSCLC). Radiother Oncol 95(2):172–177CrossRefPubMedGoogle Scholar
  10. Nawara C, Rendl G, Wurstbauer K et al (2012) The impact of PET and PET/CT on treatment planning and prognosis of patients with NSCLC treated with radiation therapy. Q J Nucl Med Mol Imaging 56:191–201PubMedGoogle Scholar
  11. Nelson C, Balter P, Morice RC et al (2008) A technique for reducing patient setup uncertainties by aligning and verifying daily positioning of a moving tumor using implanted fiducials. J Appl Clin Med Phys 9:2766CrossRefPubMedGoogle Scholar
  12. Rosenzweig KE, Sim SE, Mychalczak B, Braban LE, Schindelheim R, Leibel SA (2001) Elective nodal irradiation in the treatment of non-small-cell lung cancer with three-dimensional conformal radiation therapy. Int J Radiat Oncol Biol Phys 50:681–685CrossRefPubMedGoogle Scholar
  13. Rosenzweig KE, Sura S, Jackson A, Yorke E (2007) Involved-field radiation therapy for inoperable non small-cell lung cancer. J Clin Oncol 25:5557–5561CrossRefPubMedGoogle Scholar
  14. Underberg RW, Lagerwaard FJ, Slotman BJ, Cuijpers JP, Senan S (2005) Benefit of respiration-gated stereotactic radiotherapy for stage I lung cancer: an analysis of 4DCT datasets. Int J Radiat Oncol Biol Phys 62:554–560CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  1. 1.Department of Radiation OncologyMD Anderson Cancer CenterHoustonUSA

Personalised recommendations