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MR Spectroscopic Imaging

  • Elke Hattingen
  • Ulrich Pilatus
Part of the Medical Radiology book series (MEDRAD)

Abstract

MR spectroscopy (MRS) allows the noninvasive measurement of the concentrations from selected metabolites in vivo. Till now, MR spectroscopy is applied for specific purposes in brain tumor diagnostics. The metabolic profile of a brain tumor not only characterizes tumor entity, but it may also be crucial for prognosis and for therapeutic decisions. In the last decades, it has become evident that molecular genetic markers of a brain tumor may be prognostic or even predictive for a specific therapy (Weller et al. 2009; Reifenberger et al. 2012). Therefore, therapy of brain tumors is becoming increasingly complex, and histopathological features should not be the only aspect of establishing therapeutic decisions in the future.

Keywords

Brain Tumor Metabolite Concentration Partial Volume Effect Lipid Signal Gliomatosis Cerebri 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

ATRT

Atypical teratoid rhabdoid tumor

BCNU

Bis-chloroethylnitrosourea (carmustine)

GBM

Glioblastoma multiforme

HIF1α

Hypoxia-inducible factor 1-alpha

PFS

Progression-free survival

PNET

Primitive neuroectodermal tumor

PRESS

Point resolved spectroscopy

rGBM

Recurrent glioblastoma multiforme

STEAM

Stimulated echo acquisition mode

T

Tesla

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© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Neuroradiology, Clinic of RheinischeFriedrich-Wilhelms-UniversityBonnGermany
  2. 2.NeuroradiologyGoethe University FrankfurtFrankfurt/MainGermany

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