Nasopharyngeal Carcinoma

Part of the Medical Radiology book series (MEDRAD)


The nasopharynx is a cubodial chamber that is posteriorly bound by the C1–C2 vertebral body and sphenoid bone. Anteriorly, it connects with the nasal cavity and begins at the posterior choanae. Inferiorly, it connects with the oropharynx and the superior surface of the soft palate forms the floor of the cavity (Fig. 1a).


Cavernous Sinus Gross Tumor Volume Sphenoid Sinus Parapharyngeal Space Middle Cranial Fossa 
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  1. Abdel Khalek Abdel Razek A, King A (2012) MRI and CT of nasopharyngeal carcinoma. AJR Am J Roentgenol 198:11–18CrossRefGoogle Scholar
  2. Al-Sarraf M, LeBlanc M, Giri PG et al (1998) Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized Intergroup study 0099. J Clin Oncol 16:1310–1317CrossRefGoogle Scholar
  3. Gregoire V, Levendag P, Ang KK et al (2003) CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC, RTOG consensus guidelines. Radiother Oncol 69:227–236CrossRefGoogle Scholar
  4. Jack Baskin H Sr, Duick DS, Levine RA (2013) Thyroid ultrasound and ultrasound-guided FNA, 3rd edn. Springer, New YorkCrossRefGoogle Scholar
  5. Kam MK, Teo PM, Chau RM et al (2004) Treatment of nasopharyngeal carcinoma with intensity-modulated radiotherapy: the Hong Kong experience. Int J Radiat Oncol Biol Phys 60:1440–1450CrossRefGoogle Scholar
  6. Lee N, Harris J, Garden AS et al (2009) Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225. J Clin Oncol 27:3684–3690CrossRefGoogle Scholar
  7. Lee NY, Zhang Q, Pfister DG et al (2012) Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial. Lancet Oncol 13:172–180CrossRefGoogle Scholar
  8. Lin S, Pan J, Han L, Zhang X, Liao X, Lu JJ (2009) Nasopharyngeal carcinoma treated with reduced-volume intensity-modulated radiation therapy: report on the 3-year outcome of a prospective series. Int J Radiat Oncol Biol Phys 75:1071–1078CrossRefGoogle Scholar
  9. Ng WT, Lee AW, Kan WK et al (2007) N-staging by magnetic resonance imaging for patients with nasopharyngeal carcinoma: pattern of nodal involvement by radiological levels. Radiother Oncol 82:70–75CrossRefGoogle Scholar
  10. Su SF, Han F, Zhao C et al (2012) Long-term outcomes of early-stage nasopharyngeal carcinoma patients treated with intensity-modulated radiotherapy alone. Int J Radiat Oncol Biol Phys 82:327–333CrossRefGoogle Scholar
  11. Wang T, Riaz N, Cheng S, Lu J, Lee N (2012) Intensity-modulated radiation therapy for nasopharyngeal carcinoma: a review. J Radiat Oncol 1:129–146CrossRefGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  1. 1.Department of Radiation OncologyMemorial Sloan-Kettering Cancer CenterNew YorkUSA

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