Advanced laryngeal cases are defined here as T stages ≥3 and/or N + disease, i.e., cases for which limited larynx-only fields are not appropriate. The larynx is divided into three sites: supraglottis, glottis, and subglottis. The subglottic space extends from the first tracheal ring to 5 mm inferior to the free edge true vocal cords (TVCs). The glottic larynx contains the true vocal folds, anterior commissure, posterior commissure, and the infraglottic space (5 mm inferior to the free edge of the TVCs). The supraglottic larynx contains the following subsites of the larynx: ventricles, false vocal folds (FVCs), aryepiglottic folds, and epiglottis (infrahyoid, suprahyoid, laryngeal surface, lingual surface).
Laryngeal Cancer Total Laryngectomy Extracapsular Extension Transoral Laser Microsurgery Glottic Cancer
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Baujat B, Bourhis J, Blanchard P, et al (2010) Hyperfractionated or accelerated radiotherapy for head and neck cancer. The Cochrane Database Syst Rev 12:CD002026. doi: 10.1002/14651858.CD002026
Buckley JG, MacLennan K (2000) Cervical node metastases in laryngeal and hypopharyngeal cancer: a prospective analysis of prevalence and distribution. Head Neck 22:380–385CrossRefPubMedGoogle Scholar
Candela FC, Shah J, Jaques DP, Shah JP (1990) Patterns of cervical node metastases from squamous carcinoma of the larynx. Arch Otolaryngol Head Neck Surg 116:432–435CrossRefPubMedGoogle Scholar
Dagan R, Morris CG, Bennett JA et al (2007) Prognostic significance of paraglottic space invasion in T2N0 glottic carcinoma. Am J Clin Oncol 30:186–190CrossRefPubMedGoogle Scholar
Forastiere AA, Zhang Q, Weber RS et al (2013) Long-term results of RTOG 91-11: a comparison of three nonsurgical treatment strategies to preserve the larynx in patients with locally advanced larynx cancer. J Clin Oncol 31:845–852CrossRefPubMedGoogle Scholar
Gregoire V, Levendag P, Ang KK et al (2003) CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC, RTOG consensus guidelines. Radiother Oncol 69:227–236CrossRefGoogle Scholar
Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. The Department of Veterans Affairs Laryngeal Cancer Study Group (1991) N Engl J Med 324:1685–1690Google Scholar
Lindberg R (1972) Distribution of cervical lymph node metastases from squamous cell carcinoma of the upper respiratory and digestive tracts. Cancer 29:1446–1449CrossRefPubMedGoogle Scholar
Mendenhall WM, Morris CG, Amdur RJ, Hinerman RW, Mancuso AA (2003) Parameters that predict local control after definitive radiotherapy for squamous cell carcinoma of the head and neck. Head Neck 25:535–542CrossRefPubMedGoogle Scholar
Olsen KD (2010) Reexamining the treatment of advanced laryngeal cancer. Head Neck 32:1–7PubMedGoogle Scholar
Zhang B, Xu ZG, Tang PZ (2006) Elective lateral neck dissection for laryngeal cancer in the clinically negative neck. J Surg Oncol 93:464–467CrossRefPubMedGoogle Scholar