Hyperpolarized Gas MRI in Pediatric Lung Disease

  • Peter Komlosi
  • Jennifer L. Benjamin
  • Talissa A. Altes
Part of the Medical Radiology book series (MEDRAD)


Hyperpolarized gas magnetic resonance imaging (HG-MRI) of the lung provides high temporal and spatial resolution images of the air spaces of the lung and can be used to elucidate both lung function and morphology. Because no ionizing radiation is involved, HG-MRI is a promising technique for the evaluation of pediatric lung diseases. In this chapter, we describe briefly the basic principles of HG-MRI, review the literature of HG-MRI in three pediatric lung diseases (asthma, cystic fibrosis, and bronchopulmonary dysplasia), and discuss possible future clinical applications of hyperpolarized gas imaging in pediatric lung disease.


Cystic Fibrosis Apparent Diffusion Coefficient Bronchopulmonary Dysplasia Airway Closure Ventilation Defect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Peter Komlosi
    • 1
  • Jennifer L. Benjamin
    • 1
  • Talissa A. Altes
    • 1
  1. 1.Department of Radiology and Medical ImagingUniversity of VirginiaCharlottesvilleUSA

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