There is Evidence for the Superiority of Protons or Heavy Ions, Contra

  • Daniel Robert Henderson
  • Nicholas van As
Part of the Medical Radiology book series (MEDRAD)


Photon therapy is a safe and effective treatment for localised prostate cancer. It is used widely and has a strong evidence base. For three decades, proponents of proton and heavy ion therapy have claimed that these modalities have theoretical advantages which will translate into clinical benefit. However, there is no current evidence to support this. In this chapter we will assess the theoretical and clinical evidence for proton and heavy ion therapy and compare this with that for photon therapy. The health economic perspective will also be examined. We will show that there is no evidence for the superiority of protons or heavy ions over photon therapy.


Planning Target Volume Localise Prostate Cancer Stereotactic Body Radiotherapy Late Toxicity Relative Biological Effectiveness 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Clinical Oncology Royal Marsden Hospital LondonLondonUK
  2. 2.The Royal Marsden HospitalLondonUK

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