Contrast Medium-Induced Nephropathy

  • Henrik S. Thomsen
  • Fulvio Stacul
  • Judith A. W. Webb
Part of the Medical Radiology book series (MEDRAD)


A sudden drop in renal function after exposure to contrast media was first described more than 60 years ago. Contrast medium-induced nephropathy (CIN) is still considered an important acute adverse reaction. Despite both clinical and experimental research, its pathophysiology is still unclear. It occurs to the same extent after all non-ionic iodine-based contrast agents. Patients at increased risk are those with moderately and severely reduced renal function. Volume expansion seems to reduce the frequency, but no pharmacological manipulation has been proven to be helpful. This chapter reviews the recent information on CIN.


Chronic Kidney Disease Contrast Medium Kidney Disease Improve Global Outcome Contrast Medium Administration Nephrotoxic Potential 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Henrik S. Thomsen
    • 1
  • Fulvio Stacul
    • 2
  • Judith A. W. Webb
    • 3
  1. 1.Department of Diagnostic RadiologyCopenhagen University Hospital HerlevHerlevDenmark
  2. 2.S. C. Radiologia Ospedale MaggioreAzienda Ospedaliero-Universitaria “Ospedali Riuniti” di TriesteTriesteItaly
  3. 3.Consultant Emeritus, Diagnostic Radiology DepartmentSt. Bartholomew’s Hospital, University of LondonLondonUK

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