Contrast Media pp 193-200 | Cite as

Radiography with Gadolinium-Based Contrast Media

  • Henrik S. Thomsen
  • Peter Leander
Part of the Medical Radiology book series (MEDRAD)


The atomic weight of gadolinium renders it radio-opaque at the KeVs used for radiography. Based on the incorrect assumption that gadolinium-based contrast media were not nephrotoxic, several investigators started using gadolinium-based contrast media for radiography, including CT, in patients with reduced renal function instead of using iodine-based contrast media. Nephrotoxicity of gadolinium-based contrast agents when used for radiographic studies, CT and MRI has now been described in both man and animals with renal impairment. Nephrogenic systemic fibrosis is another important adverse reaction after some gadolinium-based contrast media in patients with renal impairment. Gadolinium-based contrast media should not be used as contrast agents for radiography, including CT, in patients with reduced renal function. Gadolinium-based contrast media may be helpful for radiography in patients with normal renal function who have had multiple severe adverse reactions to iodine-based contrast media.


Contrast Agent Contrast Medium Digital Subtraction Angiography Iodine Atom Nephrogenic Systemic Fibrosis 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of Diagnostic RadiologyCopenhagen University Hospital HerlevHerlevDenmark
  2. 2.Department of RadiologySkåne University HospitalMalmöSweden

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