Contrast Media pp 141-146 | Cite as

Late Adverse Reactions to Iodine-Based Contrast Media

  • Fulvio Stacul
  • Marie-France Bellin
Part of the Medical Radiology book series (MEDRAD)


The most commonly reported late adverse reactions to iodine-based contrast media are headache, skin rash, itching, nausea, dizziness, urticaria, fever, arm pain and gastrointestinal disturbances. When late reactions to enhanced and unenhanced CT were compared, only skin reactions occurred more frequently in the group who received contrast medium (non-ionic monomer or dimer) and skin reactions appear to account for the majority of true late reactions. Late skin reactions occur three to four times more commonly with the non-ionic dimer iodixanol than with the non-ionic monomers. Most reactions are self-limiting, resolve by 3–7 days, and appear to be T-cell mediated.


Contrast Medium Skin Reaction Pollen Season Late Reaction Intradermal Test 
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Copyright information

© Springer-Verlag Berlin Heidelberg  2014

Authors and Affiliations

  1. 1.S. C. Radiologia Ospedale Maggiore, Azienda Ospedaliero-Universitaria “Ospedali Riuniti” di TriesteTriesteItaly
  2. 2.Service de Radiologie Générale AdultesHôpital de Bicêtre, Secteur Paul BrocaLe Kremlin-Bicêtre CedexFrance

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