Contrast Media pp 105-109 | Cite as

Dialysis and Contrast Media

  • Sameh K. Morcos
Part of the Medical Radiology book series (MEDRAD)


Extracellular water soluble contrast media, whether gadolinium- or iodine-based, can be removed from the circulation by hemodialysis and less efficiently by peritoneal dialysis. Hemodialysis has no role in prevention of contrast-induced nephropathy and patients on hemodialysis do not need to receive dialysis shortly after administration of iodine-based contrast media. The administration of low stability gadolinium-based contrast media to patients receiving dialysis has been associated with development of nephrogenic systemic fibrosis. Only highly stable gadolinium-based contrast agents at the smallest possible dose should be used if contrast enhanced MR is considered essential in patients receiving dialysis. Patients already on hemodialysis should undergo a hemodialysis session as soon as practically possible after administration of gadolinium-based contrast agents.


Contrast Medium Peritoneal Dialysis Continuous Ambulatory Peritoneal Dialysis Nephrogenic Systemic Fibrosis Dialysis Fluid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Brooks MH, Barry KG (1973) Removal of iodinated contrast material by peritoneal dialysis. Nephron 12:10–14CrossRefGoogle Scholar
  2. Cruz DN, Perazella MA, Bellomo R et al (2006) Extracorporeal blood purification therapies for prevention of radiocontrast-induced nephropathy: a systematic review. Am J Kidney Dis 48:361–371PubMedCrossRefGoogle Scholar
  3. Cruz DN, Goh CY, Marenzi G et al (2012) Radiocontrast-induced nephropathy: a systematic review. Am J Med 125:66–78PubMedCrossRefGoogle Scholar
  4. Dehnarts T, Keller E, Gondolf K et al (1998) Effect of haemodialysis after contrast medium administration in patients with renal insufficiency. Nephrol Dial Transplant 13:358–362CrossRefGoogle Scholar
  5. Donally PK, Burwell N, McBurney A et al (1992) Clearance of iopamidol, a non-ionic contrast medium, by CAPD in patients with end-stage renal failure. Br J Radiol 65:1108–1113CrossRefGoogle Scholar
  6. Dörsam J, Knopp MV, Schad L et al (1995) Elimination of gadolinium-DTPA by peritoneal dialysis. Nephrol Dial Transplant 10:1228–1230PubMedGoogle Scholar
  7. Furukawa T, Ueda J, Takahashi S, Sajaguchi K (1996) Elimination of low-osmolality contrast media by haemodialysis. Acta Radiol 37:966–971PubMedCrossRefGoogle Scholar
  8. Huber W, Jeschke B, Kreymann B et al (2002) Haemodialysis for the prevention of contrast-induced nephropathy. Outcome of 31 patients with severely impaired renal function, comparison with patients at similar risk and review. Invest Radiol 37:471–481PubMedCrossRefGoogle Scholar
  9. Joffe P, Thomsen HS, Meusel M (1998) The pharmacokinetics of gadodiamide in patients with severe renal insufficiency treated conservatively or undergoing hemodialysis or continuously ambulatory peritoneal dialysis. Acad Radiol 5:491–502PubMedCrossRefGoogle Scholar
  10. Lee PT, Chou KJ, Liu CP et al (2007) Renal protection for coronary angiography in advanced renal failure patients by prophylactic hemodialysis. A randomized controlled trial. JACC 50:1015–1020PubMedCrossRefGoogle Scholar
  11. Matzkies FK, Tombach B, Kisters K et al (1999) Clearance of iopromide during haemodialysis with high and low flux membranes. Acta Radiol 40:220–223PubMedCrossRefGoogle Scholar
  12. Matzkies FK, Reinecke H, Tombach B et al (2000) Reduced iopromide elimination in hemodialysis with cuprophan membranes. Acta Radiol 41:671–673PubMedCrossRefGoogle Scholar
  13. Moon SS, Back SE, Kurkus J, Nilsson-Ehle P (1995) Haemodialysis for elimination of the non-ionic contrast medium iohexol after angiography in patients with impaired renal function. Nephron 70:430–437PubMedCrossRefGoogle Scholar
  14. Morcos SK, Thomsen HS, Webb JAW and members of the Contrast Media Safety Committee of the European Society of Urogenital Radiology (ESUR) (1999) Contrast media induced nephrotoxicity: a consensus report. Eur Radiol 9:1602–1613Google Scholar
  15. Morcos SK (1998) Contrast media induced nephrotoxicity—questions and answers. Br J Radiol 71:357–365PubMedGoogle Scholar
  16. Morcos SK (2004) Prevention of contrast media induced nephrotoxicity-the story so far. Clin Radiol 59:381–389PubMedCrossRefGoogle Scholar
  17. Morcos SK, Thomsen HS, Webb JAW and members of the Contrast Media Safety Committee of the European Society of Urogenital Radiology (ESUR) (2002) Dialysis and contrast media. Eur Radiol 12:3026–3030Google Scholar
  18. Okada S, Katagiri K, Kumazaki T, Yokoyama H (2001) Safety of gadolinium contrast agents in haemodialysis patients. Acta Radiol 42:339–341PubMedCrossRefGoogle Scholar
  19. Rodby RA (2007) Preventing complications of radiographic contrast media: is there a role for dialysis? Semin Dial 20:19–23PubMedCrossRefGoogle Scholar
  20. Sterner G, Frennby B, Mansson S et al (2000) Assessing residual renal function and efficiency of hemodialysis- an application for urographic contrast media. Nephron 85:324–333PubMedCrossRefGoogle Scholar
  21. Tombach B, Bremer C, Reimer P et al (2001) Renal tolerance of a neutral gadolinium chelate (gadobutrol) in patients with chronic renal failure. Results of a randomized study. Radiology 218:651–652PubMedCrossRefGoogle Scholar
  22. Ueda J, Furukawa T, Takahashi S, Sakaguchi K (1996) Elimination of ioversol by hemodialysis. Acta Radiol 37:826–829PubMedCrossRefGoogle Scholar
  23. Vogt B, Ferrari P, Schonholzer C et al (2001) Pre-emptive haemodialysis after radiocontrast media in patients with renal insufficiency is potentially harmful. Am J Med 111:692–698PubMedCrossRefGoogle Scholar
  24. Waaler A, Svaland M, Fauchald P et al (1990) Elimination of iohexol, a low osmolar non- ionic contrast medium, by haemodialysis in patients with chronic renal failure. Nephron 56:81–85PubMedCrossRefGoogle Scholar
  25. Younathan CM, Kaude JV, Cook MD et al (1994) Dialysis is not indicated immediately after administration of non-ionic contrast agents in patients with endstage renal disease treated by maintenance dialysis. Am J Roentgenol 163:969–971CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Diagnostic ImagingUniversity of SheffieldSheffieldUK

Personalised recommendations