Iodine-Based Contrast Medium Temperature and Adverse Reactions

  • Henrik S. Thomsen
Part of the Medical Radiology book series (MEDRAD)


Warming changes the bolus kinetics of iodine-based contrast media and the pressure needed to inject them. It may also reduce the rate of acute non-renal adverse reactions.


Contrast Agent Contrast Medium Adverse Event Rate Ionic Contrast Medium Nonrandomized Prospective Study 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Brunette J, Mongrain R, Rodés-Cabau J et al (2008) Comparartive rheology of low- and iso-osmolarity contrast agents at different temperatures. Catheter Cardiovasc Interv 71:78–83PubMedCrossRefGoogle Scholar
  2. Davenport MS, Wang CL, Bashir MR et al (2012) Rate of contrast media extravasations and allergic-like reactions: effect of extrinsic warming of low-osmolality iodinated CT contrast media to 37 °C. Radiology 262:475–484PubMedCrossRefGoogle Scholar
  3. Seeliger E, Sendeski M, Rihal CS, Persson PB (2012) Contrast-induced kidney injury: mechanisms, risk factors, and prevention. Eur Heart J 33:2007–2015PubMedCrossRefGoogle Scholar
  4. Thomsen HS, Dawson P, Tweedle MF (2014) MR and CT contrast agents for perfusion imaging and regulatory issues. In: Bammer R (ed.) MR and CT perfusion imaging: Clinical applications and theoretical principles. Lippincott Williams and Wilkins, Philadelphia (in press)Google Scholar
  5. Turner E, Kentor P, Melamed JL et al (1982) Frequency of anaphylactoid reactions during intravenous urography with radiographic contrast media at two different temperatures. Radiology 143:327–329PubMedGoogle Scholar
  6. Vergara M, Seguel S (1996) Adverse reactions to contrast media in CT: effects of temperature and ionic property. Radiology 199:363–366PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of Diagnostic RadiologyCopenhagen University Hospital HerlevHerlevDenmark

Personalised recommendations