Off-Label Use of Contrast Media: Practical Aspects

Part of the Medical Radiology book series (MEDRAD)


The chapter deals with the practical aspects and extent of off-label use of medicines, particularly the off-label use of contrast agents. A number of MR and US contrast agents lack approval for some age groups or indications. Using a contrast agent off-label can be avoided in most cases by checking the label/Summary of Product Characteristics and using another contrast agent which is approved. The physician prescribing the contrast agent must be aware of the contrast agent label/Summary of Product Characteristics and is responsible for the administration of the contrast agent in accordance with current medico-legal regulations.


Contrast Agent Gadopentetate Dimeglumine Gadolinium Chelate Gadobenate Dimeglumine Gadoxetic Acid 



European Union


Marketing Authorization Holder


Magnetic Resonance


Magnetic Resonance Imaging


Summary of Product Characteristics




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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Institute of diagnostic and interventional RadiologyKlinikum Karlsruhe Academic Teaching Hospital of the University of FreiburgKarlsruheGermany
  2. 2.Praxis für moderne Schnittbild DiagnostikGöttingenGermany

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