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Sarcoma

  • William P. Levin
  • Thomas F. DeLaney
Chapter
Part of the Medical Radiology book series (MEDRAD)

Abstract

Soft tissue sarcomas are malignant tumors that arise in the mesoderm. There are over 50 subtypes of these tumors that vary greatly in biological behavior. While small, low-grade lesions may be adequately treated by resection alone; larger, higher-grade lesions require adjuvant therapy to maximize local control. We will examine the prognostic factors that predict for disease recurrence and the role of radiation therapy in this setting. We will also examine the toxicities associated with radiation, and how this information is utilized to help or guide decision making for the treatment of soft tissue sarcomas.

Keywords

Local Recurrence Soft Tissue Sarcoma Positive Margin Regional Lymph Node Metastasis Soft Tissue Sarcoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

STS

Soft tissue sarcoma

SO

Second opinion

AJCC

American Joint Committee on Cancer

MSKCC

Memorial Sloan-Kettering Cancer Center

DFS

Disease-free survival

OS

Overall survival

MDACC

University of Texas M. D. Anderson Cancer Center

MGH

Massachusetts General Hospital

PMH

The Princess Margaret Hospital

RLNM

Regional lymph node metastases

MPNST

Malignant peripheral-nerve tumor

CI

Concordance index

LS

Liposarcoma

GPS

General postoperative sarcoma nomogram from MSKCC

DSS

Disease-specific survival

pathCR

Greater than or equal to 95 % necrosis

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Department of Radiation Oncology, Abramson Cancer CenterHospital of the University of PennsylvaniaPhiladelphiaUSA
  2. 2.Connective Tissue Oncology Center, Francis H. Burr Proton Therapy Center, Radiation OncologyMassachusetts General HospitalBostonUSA

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