HCC. Radioembolization Combined with Other Therapeutic Local and Systemic Treatment

  • Thomas Helmberger
Part of the Medical Radiology book series (MEDRAD)


Only in early stages of HCC resection, local ablative therapy, and transplantation are offering a chance of cure, whereas only a minority of patient will amenable for such a therapy. The majority of patients are presenting an intermediate or even advanced tumor stages where the therapeutic options are limited to transarterial and systemic molecular therapies. Radio embolization may augment the therapeutic armamentarium particularly in patients just not meeting the criteria for resection, percutaneous ablation or transplantation by downsizing/downgrading or in progressed disease where transarterial chemotherapy is contraindicated. Recent results of radio embolization in these settings and future directions will be discussed.


National Comprehensive Cancer Network Milan Criterion Local Ablative Therapy Sharp Trial Multimodality Treatment Concept 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



American Association for the Study of Liver Diseases


Barcelona-Clinic Liver Cancer


Best supportive care




Complete response


European Association for the Study of the Liver


Eastern Cooperative Oncology Group


European Network on Radioembolization with Yttrium-90 Resin Microspheres


European Organization for Research and Treatment of Cancer


European Society for Medical Oncology


Gadoxetic acid (Promovist®, Bayer, Germany)


Liver transplantation


National Comprehensive Cancer Network


National Cancer Institute


Partial response


Portal-vein thrombosis






Stable disease


Sorafenib HCC Assessment Randomized Protocol


Transarterial chemo-embolization


Transarterial embolization


Time to progression


United Network for Organ Sharing


Venous thrombosis


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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Institute of Diagnostic and Interventional Radiology, Neuroradiology and Nuclear MedicineKlinikum BogenhausenMunichGermany

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