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Inorganic Radionuclides for Nuclear Medicine Therapy

  • Yun-Sang Lee
  • Jae Min Jeong
Chapter
Part of the Medical Radiology book series (MEDRAD)

Abstract

The most commonly used radionuclides for therapy are beta emitters which have shorter penetration depth than gamma emitters. Alpha or Auger emitters also are studied for higher efficiency within shorter range. Most of these radionuclides for therapy are metals and these should be labeled to specific ligands such as peptides or proteins via bifunctional chelating agents conjugated to them. Selection of the bifunctional chelating agents generally based on the dissociation constants with target metallic radionuclides. For the improved efficiency of radionuclide therapy, intensive studies about development of new ligands and labeling methods are required.

Keywords

Auger Electron Peptide Receptor Radionuclide Therapy Radionuclide Therapy Label Monoclonal Antibody Auger Electron Emitter 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg  2012

Authors and Affiliations

  1. 1.Department of Nuclear MedicineSeoul National University College of MedicineSeoulKorea

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