Radiopeptide Therapy of Brain Tumors

  • Flavio Forrer
  • Dominik Cordier
Part of the Medical Radiology book series (MEDRAD)


 The following chapter summarizes the results of the phase I and II studies that have been published dealing with radiopeptide therapy in brain tumors. To date, three radiopeptides conjugated with a chelator for radiolabeling with radiometals or labeled directly with 131I have been used in patients. Radiopeptide therapy for brain tumors has to be regarded as experimental. So far, the largest number of patients has been treated with substance P radiolabeled with 90Y, 177Lu, or 213Bi. Besides substance P, the somatostatin analog DOTATOC and the synthetic chlorotoxin TM-601 have been used for this therapy strategy.


Malignant Glioma Resection Cavity Triacetic Acid Effective Dose Range Radiopeptide Therapy 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Deputy Head Department of Nuclear MedicineUniversity Hospital BaselBaselSwitzerland
  2. 2.Senior Physician Department of NeurosurgeryUniversity HospitalBaselSwitzerland

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