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Cerebral Vasculitis

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Inflammatory Diseases of the Brain

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Vasculitis is an inflammation of blood vessels due to various origins. Vessels of the peripheral and/or central nervous systems may be involved. Clinical and radiological diagnosis of cerebral vasculitis is challenging as there is no vasculitis-specific symptom or imaging sign. Furthermore, it may mimic other neurological diseases, which would require different treatment approaches. Neuroimaging of cerebral vasculitis should begin with initial MRI to assess the degree of parenchymal damage and to detect vessel wall changes. If the results are indefinite DSA should be pursued in order to detect potential changes of medium-sized vessels. Vasculitides of small vessels cannot be detected by vascular imaging and require brain or leptomeningeal biopsy.

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References

  • Aksel S (2001) Vasculitis of the nervous system. J Neurol 248:451–468

    Article  Google Scholar 

  • Berlit P (2004) Cerebral vasculitis. Nervenarzt 75:817–830

    PubMed  CAS  Google Scholar 

  • Birnbaum J, Hellmann DB (2009) Primary angiitis of the central nervous system. Arch Neurol 66:704–709

    Article  PubMed  Google Scholar 

  • Bley TA, Wieben O, Uhl M, Thiel J, Schmidt D, Langer M (2005) High-resolution MRI in giant cell arteritis: imaging of the wall of the superficial temporal artery. Am J Roentgenol 184:283–287

    Article  Google Scholar 

  • di Comite G, Sabbadini MG (2005) Neurological involvement in rheumatological diseases. Neurol Sci 26(Suppl 1):S9–S14

    Article  PubMed  Google Scholar 

  • Ducros A, Fiedler U, Porcher R, Boukobza M, Stapf C, Bousser MG (2010) Hemorrhagic manifestations of reversible cerebral vasoconstriction. Stroke 41(11):2505–2511

    Article  PubMed  Google Scholar 

  • Ertl-Wagner B (2007) Pädiatrische Neuroradiologie. Springer, Berlin, pp 200–201

    Book  Google Scholar 

  • Ferro JM (1998) Vasculitis of the central nervous system. J Neurol 245:766–776

    Article  PubMed  CAS  Google Scholar 

  • Giannini C, Salvarani C, Hunder G, Brown R (2012) Primary central nervous system vasculitis: pathology and mechanisms. Acta Neuropathol 123(6):759–772 (*this recent review by authors from the Mayo Clinic gives a very detailed overview about clinical and imaging signs of PCNSV)

    Google Scholar 

  • Jennette JC, Falk RJ, Andrassy K, Bacon PA, Churg J, Gross WL, Hagen EC, Hoffman GS, Hunder GG, Kallenberg CG et al (1994) Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum, vol 37, pp 187–192

    Google Scholar 

  • Kelley RE (2004) CNS vasculitis. Front Biosci 9:946–955

    Article  PubMed  CAS  Google Scholar 

  • Kueker W (2007) Cerebral vasculitis: imaging signs revisited. Neuroradiology 49:471–479

    Article  Google Scholar 

  • Kueker W, Gaertner S, Nagele T, Dopfer C, Schoning M, Fiehler J, Rothwell PM, Herrlinger U (2008) Vessel wall contrast enhancement: a diagnostic sign of cerebral vasculitis. Cerebrovasc Dis 26:23–29

    Article  Google Scholar 

  • Moore PM, Richardson B (1998) Neurology of the vasculitides and connective tissue diseases. J Neurol Neurosurg Psychiatry 65:10–22

    Article  PubMed  CAS  Google Scholar 

  • Pipitone N, Versari A, Salvarani C (2008) Role of imaging studies in the diagnosis and follow-up of large-vessel vasculitis: an update. Rheumatology (Oxford) 47:403–408

    Google Scholar 

  • Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Weigand SD, Miller DV, Giannini C, Meschia JF, Huston J 3rd, Hunder GG (2007) Primary central nervous system vasculitis: analysis of 101 patients. Ann Neurol 62(5):442–451

    Article  PubMed  Google Scholar 

  • Salvarani C, Brown RD Jr, Hunder GG (2012) Adult primary central nervous system vasculitis: an update. Curr Opin Rheumatol 24:46–52 (*A nice review providing an extensive description of several subsets of PCNSV including neuroimaging and disease management)

    Google Scholar 

  • Sattar A, Manousakis G, Jensen MB (2010) Systematic review of reversible cerebral vasoconstriction syndrome. Expert Rev Cardiovasc Ther 8(10):1417–1421

    Google Scholar 

  • Younger DS (2004b) Vasculitis of the nervous system. Curr Opin Neurol 17:317–336

    Article  PubMed  Google Scholar 

  • Wengenroth M, Hoeltje J, Repenthin J, Meyer TN, Bonk F, Becker H, Faiss S, Stammel O, Urban PP, Bruening R (2013) Central nervous system involvement in adults with epidemic hemolytic uremic syndrome (HUS). AJNR

    Google Scholar 

  • Zuccoli G, Pipitone N, Haldipur A et al (2011) Imaging findings in primary central nervous system vasculitis. Clin Exp Rheumatol 29(Suppl. 64):S104–S109

    PubMed  Google Scholar 

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Correspondence to Martina Wengenroth .

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© 2012 Springer-Verlag Berlin Heidelberg

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Wengenroth, M., Jacobi, C., Wildemann, B. (2012). Cerebral Vasculitis. In: Hähnel, S. (eds) Inflammatory Diseases of the Brain. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2012_661

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  • DOI: https://doi.org/10.1007/174_2012_661

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-30519-1

  • Online ISBN: 978-3-642-30520-7

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