Adrenal Metastasis

  • Mirna Abboud
  • Simon S. Lo
  • Arnold C. Paulino
  • Daniel  E. Lehane
  • Bin S. Teh
Part of the Medical Radiology book series (MEDRAD)


Adrenal metastases can arise from multiple malignancies, mainly lung, breast, renal, gastric, hepatocellular carcinomas, melanoma, and many others. The greatest risk for spread to the adrenal glands is seen with lung carcinoma (Abrams et al., Cancer 3:74–85, 1950). Multiple treatment options are available to treat adrenal metastases, including open and laparoscopic adrenalectomy, radiofrequency ablation, transarterial chemoembolization, palliative radiation, and more recently stereotactic body radiation therapy (SBRT). Here we discuss the role and the benefit of SBRT in the management of adrenal metastases, including technical aspects, clinical applications, and treatment toxicities. We also include clinical case examples to illustrate the treatment plan, isodose lines, and dose–volume histograms. We conclude with future directions in the use of SBRT for adrenal metastases.


Positron Emission Tomography Stereotactic Body Radiation Therapy Gross Tumor Volume Laparoscopic Adrenalectomy Adrenal Metastasis 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Mirna Abboud
    • 1
  • Simon S. Lo
    • 2
  • Arnold C. Paulino
    • 1
  • Daniel  E. Lehane
    • 3
  • Bin S. Teh
    • 1
  1. 1.Department of Radiation Oncology, The Methodist HospitalCancer Center and Research InstituteHoustonUSA
  2. 2.Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer CenterCase Western Reserve UniversityClevelandUSA
  3. 3.Department of Academic MedicineThe Methodist HospitalHoustonUSA

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