Drugs Used in Vascular Interventional Radiology

  • Gordon Dent
  • Mark G. Cowling
Part of the Medical Radiology book series (MEDRAD)


With the growing complexity of vascular interventional radiology, a larger array of drug treatments is employed by practitioners undertaking these procedures. Furthermore, patients attending for treatment are likely to be on combinations of drugs which may interact with medications employed during endovascular procedures. This chapter describes the mechanisms of action of drugs commonly used in this patient group and illustrates the likely interactions that may be encountered during endovascular procedures.


Insulin Glargine Insulin Lispro Antiplatelet Drug Vascular Intervention Isosorbide Dinitrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Cattaneo M, Podda GM (2010) State of the art of new \(\hbox{P}_{{2Y}_{12}}\) antagonists. Intern Emerg Med 5:385–391Google Scholar
  2. Chang WS, Wardell MR, Lomas DA, Carrell RW (1996) Probing serpin reactive-loop conformations by proteolytic cleavage. Biochem J 314:647–653PubMedGoogle Scholar
  3. Coggins MP, Bloch KD (2007) Nitric oxide in the pulmonary vasculature. Arterioscler Thromb Vasc Biol 27:1877–1885CrossRefGoogle Scholar
  4. Dirkmann D, Görlinger K, Gisbertz C, Dusse F, Peters J (2012) Factor XIII and tranexamic acid but not recombinant factor VIIa attenuate tissue plasminogen activator-induced hyperfibrinolysis in human whole blood. Anesth Analg. doi: 10.1213/ANE.0b013e31823b6683 (Epub ahead of print)
  5. Duncker DJ, Bache RJ (2008) Regulation of coronary blood flow during exercise. Physiol Rev 88:1009–1086PubMedCrossRefGoogle Scholar
  6. Eriksson BI, Borris LC, Friedmann RJ, Haas S, Huisman MV, Kakkar AK, Bandel TJ, Beckmann H, Mühlhofer E, Misselwitz F, Geerts W, RECORD1 Study Group (2008) Rivaroxaban versus exoxaparin for thromboprophylaxis after hip arthroplasty. N Engl J Med 358:2675–2775Google Scholar
  7. Hippisley-Cox J, Coupland C (2010) Individualising the risks of statins in men and women in England and Wales: population-based cohort study. Heart 96:939–947PubMedCrossRefGoogle Scholar
  8. Hirsch J, O’Donnell M, Weitz JI (2005) New anticoagulants. Blood 105:453–463CrossRefGoogle Scholar
  9. Hudson TL, Dukes SF, Reilly K (2006) Use of local anesthesia for arterial punctures. Am J Crit Care 15:595–599PubMedGoogle Scholar
  10. Krentz AJ, Bailey CJ (2005) Oral antidiabetic agents: current role in type 2 diabetes mellitus. Drugs 65:385–411PubMedCrossRefGoogle Scholar
  11. Lemon SJ Jr, Crannage AJ (2011) Pharmacologic anticoagulation reversal in the emergency department. Adv Emerg Nurs J 33:212–223PubMedGoogle Scholar
  12. Mager A, Strasberg B, Rechavia E, Birnbaum Y, Mazur A, Yativ N, Sclarovsky S (1994) Clinical significance and predisposing factors to symptomatic bradycardia and hypotension after percutaneous transluminal coronary angioplasty. Am J Cardiol 74:1085–1088PubMedCrossRefGoogle Scholar
  13. Mayfield JA, White RD (2004) Insulin therapy for type 2 diabetes: rescue, augmentation, and replacement of beta-cell function. Am Fam Physician 70:489–500PubMedGoogle Scholar
  14. NICE (2011) Hypertension: clinical management of primary hypertension in adults (NICE clinical guideline 127). National Institute for Health and Clinical Excellence, LondonGoogle Scholar
  15. Olkolla KT, Ahonen J (2008) Midazolam and other benzodiazepines. Handb Exp Pharmacol 182:335–360CrossRefGoogle Scholar
  16. Rao SV, Ohman EM (2010) Anticoagulant therapy for percutaneous coronary intervention. Circ Cardiovasc Interv 3:80–88Google Scholar
  17. Royal College of Physicians (2011) Type 2 diabetes: national clinical guideline for management in primary and secondary care (update). Royal College of Physicians, LondonGoogle Scholar
  18. Royal College of Radiologists (2010) Standards for intravascular contrast agent administration to adult patients, 2nd edn. Royal College of Radiologists, LondonGoogle Scholar
  19. Sangkuhl K, Klein TE, Altman RB (2010) Clopidogrel pathway. Pharmacogenet Genomics 20:463–465PubMedGoogle Scholar
  20. Schlicker E, Kathmann M (2008) Presynaptic neuropeptide receptors. Handb Exp Pharmacol 184:409–434PubMedCrossRefGoogle Scholar
  21. Shearer MJ, Newman P (2008) Metabolism and cell biology of vitamin K. Thromb Hemost 100:530–547Google Scholar
  22. Smith SW (2010) Drugs and pharmaceuticals: management of intoxication and antidotes. EXS 100:397–460PubMedGoogle Scholar
  23. Thomsen HS, Morcos SK (2003) Contrast media and the kidney: European Society of Urogenital Radiology (ESUR) guidelines. Br J Radiol 76:513–518PubMedCrossRefGoogle Scholar
  24. Vitrat N, Letestu R, Massé R, Lazar V, Vainchenker W, Debili N (2000) Thromboxane synthase has the same pattern of expression as platelet specific glycoproteins during human megakaryocyte differentiation. Thromb Hemost 83:759–768Google Scholar
  25. Weirich J, Antoni H (1998) Rate-dependence of antiarrhythmic and proarrhythmic properties of class I and class III antiarrhythmic drugs. Basic Res Cardiol 93(Suppl 1):125–132PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Institute of Science and Technology in MedicineKeele UniversityKeeleUK
  2. 2.University Hospital of North StaffordshireStoke-on-TrentUK

Personalised recommendations