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MRI-Guided Stem Cell Therapy

  • Chapter
Interventional Magnetic Resonance Imaging

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

  • 2011 Accesses

Abstract

In the past several decades, there has been great interest in the transplantation of stem cells to recapitulate organs with limited regenerative capacity. During this same period, the ability to image stem cells by labeling with MRI-visible contrast agents has proved to be an enabling technology for determining the engraftment and fate of these cells. A natural extension of MR-labeling of stem cells is the delivery of stem cells using MR interventional techniques. While the development of these interventional techniques is hindered in part by the need to develop user-friendly imaging interfaces, MR-compatible devices, and advanced physiologic monitoring capabilities, limited clinical trials with MR-labeled stem cells have been performed that suggest MR interventional techniques will offer a safe and more effective method to deliver the stem cell therapies.

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Authors and Affiliations

  1. Siemens Corporate Research, Center for Applied Medical Imaging, Baltimore, MD, USA

    Tina Ehtiati

  2. Russell H. Morgan Department of Radiology and Radiological Science, Department of Molecular and Comparative Pathobiology, Johns Hopkins University, Baltimore, MD, USA

    Dara L. Kraitchman

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  1. Tina Ehtiati
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  2. Dara L. Kraitchman
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Correspondence to Dara L. Kraitchman .

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  1. , Diagnostic and Interventional Radiology, Leipzig University Hospital, Liebigstrasse 20, Leipzig, 04103, Sachsen, Germany

    Thomas Kahn

  2. , Diagnostic and Interventional Radiology, Leipzig University Hospital, Liebigstrasse 20, Leipzig, 04103, Sachsen, Germany

    Harald Busse

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Ehtiati, T., Kraitchman, D.L. (2012). MRI-Guided Stem Cell Therapy. In: Kahn, T., Busse, H. (eds) Interventional Magnetic Resonance Imaging. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2012_605

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  • DOI: https://doi.org/10.1007/174_2012_605

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