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PET/CT Interpretation

  • Patrick J. Peller
Part of the Medical Radiology book series (MEDRAD)

Abstract

PET/SPECT interpretation is a challenging task, which is aided by a systematic approach to image review. The PET/SPECT report is the final product of interpretation and needs to be crafted carefully. The impression should answer the referring physician's clinical question and delineate all diagnoses requiring his action. A thorough knowledge of the normal distribution of FDG is very important for PET/CT interpretation.

Keywords

Maximum Intensity Projection Image Mylohyoid Muscle Blood Pool Activity Bone Marrow Activity Smooth Muscle Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. ACR practice guideline for performing FDG-PET/CT in oncology. http://www.acr.org/SecondaryMainMenuCategories/quality_safety/guidelines/nuc_med/fdg_pet_ct.aspx. Accessed 10 Jan 2012
  2. Agress H Jr, Wong TZ, Shreve P (2008) Interpretation and reporting of positron emission tomography-computed tomographic scans. Semin Ultrasound CT MR 29(4):283–90PubMedCrossRefGoogle Scholar
  3. Ak I, Stokkel MP, Pauwels EK (2000) Positron emission tomography with 2-[18F]fluoro-2-deoxy-d-glucose in oncology. Part II. The clinical value in detecting and staging primary tumours. J Cancer Res Clin Oncol 126(10):560–74PubMedCrossRefGoogle Scholar
  4. Brink I, Reinhardt MJ, Hoegerle S, Altehoefer C, Moser E, Nitzsche EU (2001) Increased metabolic activity in the thymus gland studied with 18F-FDG PET: age dependency and frequency after chemotherapy. J Nucl Med 42(4):591–5PubMedGoogle Scholar
  5. CMS released Transmittals R108 NCD; R1833 CP rescinding transmittals R106 NCD and R1817 CP. http://www.cms.gov/transmittals/downloads/R108NCD.pdf. Accessed 10 Jan 2012
  6. Coleman RE, Hillner BE, Shields AF et al (2010) PET and PET/CT reports: observations from the National Oncologic PET Registry. J Nucl Med 51:158–163PubMedCrossRefGoogle Scholar
  7. Culverwell AD, Scarsbrook AF, Chowdhury FU (2011) False-positive uptake on 2-[18F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography/computed tomography (PET/CT) in oncological imaging. Clin Radiol 66(4):366–82PubMedCrossRefGoogle Scholar
  8. Dilsizian V, Bacharach SL, Khin MM, Smith MF (2001) Fluorine-18-deoxyglucose SPECT and coincidence imaging for myocardial viability: clinical and technologic issues. J Nucl Cardiol 8(1):75–88PubMedCrossRefGoogle Scholar
  9. El-Haddad G, Alavi A, Mavi A, Bural G, Zhuang H (2004) Normal variants in [18F]-fluorodeoxyglucose PET imaging. Radiol Clin North Am 42(6):1063–81PubMedCrossRefGoogle Scholar
  10. Ferdinand B, Gupta P, Kramer EL (2004) Spectrum of thymic uptake at 18F-FDG PET. Radiographics 24(6):1611–6PubMedCrossRefGoogle Scholar
  11. Goerres GW, Von Schulthess GK, Hany TF (2002) Positron emission tomography and PET/CT of the head and neck: FDG uptake in normal anatomy, in benign lesions, and in changes resulting from treatment. AJR Am J Roentgenol 179(5):1337–43PubMedGoogle Scholar
  12. Gontier E, Fourme E, Wartski M, Blondet C, Bonardel G, Le Stanc E, Mantzarides M, Foehrenbach H, Pecking AP, Alberini JL (2008) High and typical 18F-FDG bowel uptake in patients treated with metformin. Eur J Nucl Med Mol Imaging 35(1):95–9PubMedCrossRefGoogle Scholar
  13. Hicks RJ, Binns D, Stabin MG (2001) Pattern of uptake and excretion of (18)F-FDG in the lactating breast. J Nucl Med 42(8):1238–42PubMedGoogle Scholar
  14. Israel O, Yefremov N, Bar-Shalom R, Kagana O, Frenkel A, Keidar Z, Fischer D (2005) PET/CT detection of unexpected gastrointestinal foci of 18F-FDG uptake: incidence, localization patterns, and clinical significance. J Nucl Med 46(5):758–62PubMedGoogle Scholar
  15. Kamel EM, Jichlinski P, Prior JO, Meuwly JY, Delaloye JF, Vaucher L, Malterre J, Castaldo S, Leisinger HJ, Delaloye AB (2006) Forced diuresis improves the diagnostic accuracy of 18F-FDG PET in abdominopelvic malignancies. J Nucl Med 47(11):1803–7PubMedGoogle Scholar
  16. Karantanis D, Bogsrud TV, Wiseman GA, Mullan BP, Subramaniam RM, Nathan MA, Peller PJ, Bahn RS, Lowe VJ (2007) Clinical significance of diffusely increased 18F-FDG uptake in the thyroid gland. J Nucl Med 48(6):896–901PubMedCrossRefGoogle Scholar
  17. Kitajima K, Nakamoto Y, Senda M, Onishi Y, Okizuka H, Sugimura K (2007) Normal uptake of 18F-FDG in the testis: an assessment by PET/CT. Ann Nucl Med 21(7):405–10PubMedCrossRefGoogle Scholar
  18. Kostakoglu L, Agress H Jr, Goldsmith SJ (2003) Clinical role of FDG PET in evaluation of cancer patients. Radiographics 23(2):315–40PubMedCrossRefGoogle Scholar
  19. Lerman H, Metser U, Grisaru D, Fishman A, Lievshitz G, Even-Sapir E (2004) Normal and abnormal 18F-FDG endometrial and ovarian uptake in pre- and postmenopausal patients: assessment by PET/CT. J Nucl Med 45(2):266–71PubMedGoogle Scholar
  20. Nakamoto Y, Tatsumi M, Hammoud D, Cohade C, Osman MM, Wahl RL (2005) Normal FDG distribution patterns in the head and neck: PET/CT evaluation. Radiology 234(3):879–85PubMedCrossRefGoogle Scholar
  21. Ozülker T, Ozülker F, Mert M, Ozpaçaci T (2010) Clearance of the high intestinal (18)F-FDG uptake associated with metformin after stopping the drug. Eur J Nucl Med Mol Imaging 37(5):1011–7PubMedCrossRefGoogle Scholar
  22. Reiner BI, Knight N, Siegel EL (2007) Radiology reporting, past, present, and future: the radiologist’s perspective. J Am Coll Radiol 4:313–319PubMedCrossRefGoogle Scholar
  23. Skehan SJ, Brown AL, Thompson M, Young JE, Coates G, Nahmias C (2000) Imaging features of primary and recurrent esophageal cancer at FDG PET. Radiographics 20(3):713–23PubMedGoogle Scholar
  24. SNM PET pros, elements of PET/CT reporting. http://www.snm.org/docs/PET_PROS/ElementsofPETCTReporting.pdf. Accessed 10 Jan 2012
  25. Tatlidil R, Jadvar H, Bading JR, Conti PS (2002) Incidental colonic fluorodeoxyglucose uptake: correlation with colonoscopic and histopathologic findings. Radiology 224(3):783–7PubMedCrossRefGoogle Scholar
  26. Townsend DW (2008) Combined positron emission tomography-computed tomography: the historical perspective. Semin Ultrasound CT MR 29(4):232–5PubMedCrossRefGoogle Scholar
  27. Vranjesevic D, Schiepers C, Silverman DH, Quon A, Villalpando J, Dahlbom M, Phelps ME, Czernin J (2003) Relationship between 18F-FDG uptake and breast density in women with normal breast tissue. J Nucl Med 44(8):1238–42PubMedGoogle Scholar
  28. Zhuang H, Kumar R, Mandel S, Alavi A (2004) Investigation of thyroid, head, and neck cancers with PET. Radiol Clin North Am 42(6):1101–11PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Division of Nuclear MedicineDepartment of Radiology, Mayo ClinicRochesterUSA

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