MRI-Guided Laser Ablation in the Liver

Part of the Medical Radiology book series (MEDRAD)


Hepatic invasive thermal ablation procedures benefit from MRI guidance. Advantageous properties of MRI are liver diagnostic criteria utilizing organ-specific contrast agents, multiplanar reconstruction, and particularly the ability to perform thermometry. Currently, MRI guidance of invasive ablation modalities in a clinical setting is limited to laser and radio-frequency ablation because of limited magnetic resonance (MR) compatibility of microwave ablation and cryoablation. Laser ablation represents a smaller group of interventional approaches as compared with radio-frequency ablation but is thought to be better suited for MR thermometry, showing no imaging interference or instrumentation artifacts. The Greifswald model of therapy monitoring utilizes state-of-the-art proton-resonance-frequency-shift-based thermometry to achieve fair correlation between online mapping of lethal impact and ensuing tissue necrosis. The possibility of device-independent online therapy control is an important criterion to meet oncologic standards and therefore the needs of the interventional radiologist in his or her role as an oncologic therapist.


Laser Ablation Laser Fiber Thermal Ablation Bayer HealthCare Pharmaceutical Magnetic Resonance Thermometry 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  1. 1.Department of Diagnostic Radiology and NeuroradiologyGreifswald University MedicineGreifswaldGermany

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