Historical Background, Anatomy and Function, Etiology and Epidemiology
This introduction presents the history of the recognition of the appendix as the organ responsible for a disease with a high mortality rate in the previous century and called acute appendicitis. This history reveals examples of resistance to changing concepts and brilliant early observations that were not easily accepted in the medical community. The anatomy of the appendix is nowadays well known but its function remains unclear. Acute appendicitis is the most common cause of acute abdominal pain that requires surgery but, for a disease that is prevalent and apparently simple, there is currently little that is well established on its etiology.
KeywordsAcute Appendicitis Vasoactive Intestinal Peptide Acute Abdominal Pain Normal Appendix Negative Appendectomy
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