Skip to main content

Imaging the Infertile Male-1: Varicocele

  • Chapter
  • 2294 Accesses

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Color doppler ultrasound is the imaging modality of choice to evaluate patients with varicocele. In order to assess correctly the extension of the disease and the characteristics of flow, the patient should be examined supine and while standing, at rest and during Valsalva’s maneuver. Several classification can be used to grade varicocele based on position of the dilated vessels and characteristics of flow. Besides color doppler ultrasound spectral analysis is important to assess reflux duration. Experimental studies showed that varicocele causes flow changes in the testicular flows, but investigation in men requires validation. While extratesticular varicocele is relatively common, intratesticular varicocele is rare. Abdominal masses may cause not compressible secondary varicocele. CT and MR imaging are usually not indicated for evaluation of varicocele, but this condition may be recognized in case of examinations performed for other purposes. Scintigraphy and thermography have no current clinical role, while venography is usually performed as a part of percutaneous sclerotherapy.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • World Health Organization (1985) Comparison among different methods for the diagnosis of varicocele. Fertil Steril 43:575–582

    Google Scholar 

  • Abduljaleel PM, Al-Mulhim F, Nouman A et al (2006) Intratesticular varicocele and extratesticular varicocele in a patient with nephrotic syndrome complicated by left renal vein thrombosis. Ann Saudi Med 26:228–230

    PubMed  Google Scholar 

  • Alukal JP, Zurakowski D, Atala A et al (2005) Testicular hypotrophy does not correlate with grade of adolescent varicocele. J Urol 174:2367–2370 discussion 2370

    Article  PubMed  Google Scholar 

  • Atasoy C, Fitoz S (2001) Gray-scale and color doppler sonographic findings in intratesticular varicocele. J Clin Ultrasound 29:369–373

    Article  PubMed  CAS  Google Scholar 

  • Aydos K, Baltaci S, Salih M et al (1993) Use of color doppler sonography in the evaluation of varicoceles. Eur Urol 24:221–225

    PubMed  CAS  Google Scholar 

  • Basile-Fasolo C, Izzo PL, Canale D et al (1986) Doppler sonography, contact scrotal thermography and venography: a comparative study in evaluation of subclinical varicocele. Int J Fertil 30:62–64

    PubMed  CAS  Google Scholar 

  • Beddy P, Geoghegan T, Browne RF et al (2005) Testicular varicoceles. Clin Radiol 60:1248–1255

    Article  PubMed  CAS  Google Scholar 

  • Bhatt S, Rubens DJ, Dogra VS (2006) Sonography of benign intrascrotal lesions. Ultrasound Q 22:121–136

    Article  PubMed  Google Scholar 

  • Biagiotti G, Cavallini G, Modenini F et al (2002) Spermatogenesis and spectral echo-colour doppler traces from the main testicular artery. BJU Int 90:903–908

    Article  PubMed  CAS  Google Scholar 

  • Bucci S, Liguori G, Amodeo A et al (2008) Intratesticular varicocele: evaluation using grey scale and color doppler ultrasound. World J Urol 26:87–89

    Article  PubMed  Google Scholar 

  • Callea A, Berardi B, Dilorenzo V et al (1997) Echo-color doppler in the topographic study of varicocele. Arch Ital Urol Androl 69:189–192

    PubMed  CAS  Google Scholar 

  • Carlsen E, Andersen AG, Buchreitz L et al (2000) Inter-observer variation in the results of the clinical andrological examination including estimation of testicular size. Int J Androl 23:248–253

    Article  PubMed  CAS  Google Scholar 

  • Chiou RK, Anderson JC, Wobig RK et al (1997) Color Doppler ultrasound criteria to diagnose varicoceles: correlation of a new scoring system with physical examination. Urology 50:953–956

    Article  PubMed  CAS  Google Scholar 

  • Conti E, Fasolo PP, Sebastiani G et al (2005) Color doppler sonography in the intratesticular varicocele. Arch Ital Urol Androl 77:63–65

    PubMed  Google Scholar 

  • Cornud F, Belin X, Amar E et al (1999) Varicocele: strategies in diagnosis and treatment. Eur Radiol 9:536–545

    Article  PubMed  CAS  Google Scholar 

  • Das KM, Prasad K, Szmigielski W et al (1999) Intratesticular varicocele: evaluation using conventional and doppler sonography. Am J Roentgenol 173:1079–1083

    CAS  Google Scholar 

  • Dee KE, Deck AJ, Waitches GM (2000) Intratesticular pseudoaneurysm after blunt trauma. Am J Roentgenol 174:1136

    CAS  Google Scholar 

  • DemIrbas M, Ellergezen A, BI CY et al (2001) Intratesticular varicocele treated with percutaneous embolization. Urology 58:1058

    Article  PubMed  CAS  Google Scholar 

  • Diamond DA, Roth JA, Cilento BG et al (2004) Intratesticular varicocele in adolescents: a reversible anechoic lesion of the testis. J Urol 171:381–383

    Article  PubMed  Google Scholar 

  • Dogra VS, Gottlieb RH, Oka M et al (2003) Sonography of the scrotum. Radiology 227:18–36

    Article  PubMed  Google Scholar 

  • Dubin L, Amelar RD (1970) Varicocele size and results of varicocelectomy in selected subfertile men with varicocele. Fertil Steril 21:606–609

    PubMed  CAS  Google Scholar 

  • Erdogan N, Ekmekcioglu O, Baykara M (2003) Bilateral intratesticular varicocele in a patient with a history of bilateral cryptorchidism. Turk J Med Sci 33:117–119

    Google Scholar 

  • Eskew LA, Watson NE, Wolfman N et al (1993) Ultrasonographic diagnosis of varicoceles. Fertil Steril 60:693–697

    PubMed  CAS  Google Scholar 

  • Gat Y, Zukerman ZV, Bachar GN et al (2003) Adolescent varicocele: is it a unilateral disease? Urology 62:742–746 discussion 746–747

    Article  PubMed  Google Scholar 

  • Gat Y, Bachar GN, Zukerman Z et al (2004) Varicocele: a bilateral disease. Fertil Steril 81:424–429

    Article  PubMed  Google Scholar 

  • Gat Y, Zukerman Z, Chakraborty J et al (2005) Varicocele, hypoxia and male infertility. Fluid Mechanics analysis of the impaired testicular venous drainage system. Hum Reprod 20:2614–2619

    Article  PubMed  Google Scholar 

  • Geatti O, Gasparini D, Shapiro B (1991) A comparison of scintigraphy, thermography, ultrasound and phlebography in grading of clinical varicocele. J Nucl Med 32:2092–2097

    PubMed  CAS  Google Scholar 

  • Gonda RL Jr, Karo JJ, Forte RA et al (1987) Diagnosis of subclinical varicocele in infertility. Am J Roentgenol 148:71–75

    Google Scholar 

  • Graif M, Hauser R, Hirshebein A et al (2000) Varicocele and the testicular-renal venous route: hemodynamic doppler sonographic investigation. J Ultrasound Med 19:627–631

    PubMed  CAS  Google Scholar 

  • Grasso Leanza F, Pepe P, Panella P et al (1997) Volocimetric evaluation of spermatic vessels with echo color doppler in patients with idiopathic varicocele. Minerva Urol Nefrol 49:179–182

    PubMed  CAS  Google Scholar 

  • Hargreave TB, Liakatas J (1991) Physical examination for varicocele. Br J Urol 67:328

    Article  PubMed  CAS  Google Scholar 

  • Harrison RM, Lewis RW, Roberts JA (1983) Testicular blood flow and fluid dynamics in monkeys with surgically induced varicoceles. J Androl 4:256–260

    PubMed  CAS  Google Scholar 

  • Harrison RM, Lewis RW, Roberts JA (1986) Pathophysiology of varicocele in nonhuman primates: long-term seminal and testicular changes. Fertil Steril 46:500–510

    PubMed  CAS  Google Scholar 

  • Hirsh AV, Cameron KM, Tyler JP et al (1980) The Doppler assessment of varicoceles and internal spermatic vein reflux in infertile men. Br J Urol 52:50–56

    Article  PubMed  CAS  Google Scholar 

  • Hoekstra T, Witt MA (1995) The correlation of internal spermatic vein palpability with ultrasonographic diameter and reversal of venous flow. J Urol 153:82–84

    Article  PubMed  CAS  Google Scholar 

  • Hsu HS, Chang LS, Chen MT et al (1994) Decreased blood flow and defective energy metabolism in the varicocele-bearing testicles of rats. Eur Urol 25:71–75

    PubMed  CAS  Google Scholar 

  • Hussein AF (2006) The role of color doppler ultrasound in prediction of the outcome of microsurgical subinguinal varicocelectomy. J Urol 176:2141–2145

    Article  PubMed  Google Scholar 

  • Jarow JP (2001) Effects of varicocele on male fertility. Hum Reprod Update 7:59–64

    Article  PubMed  CAS  Google Scholar 

  • Liguori G, Trombetta C, Garaffa G et al (2004) Color doppler ultrasound investigation of varicocele. World J Urol 22:378–381

    Article  PubMed  Google Scholar 

  • Liguori G, Ollandini G, Pomara G et al (2010) Role of renospermatic basal reflow and age on semen quality improvement after sclerotization of varicocele. Urology 75:1074–1078

    Article  PubMed  Google Scholar 

  • Lund L, Nielsen AH (1994) Color doppler sonography in the assessment of varicocele testis. Scand J Urol Nephrol 28:281–285

    PubMed  CAS  Google Scholar 

  • Marks JL, McMahon R, Lipshultz LI (1986) Predictive parameters of successful varicocele repair. J Urol 136:609–612

    PubMed  CAS  Google Scholar 

  • Marsman JW (1985) Clinical versus subclinical varicocele: venographic findings and improvement of fertility after embolization. Radiology 155:635–638

    PubMed  CAS  Google Scholar 

  • Meacham RB, Townsend RR, Rademacher D et al (1994) The incidence of varicoceles in the general population when evaluated by physical examination, gray scale sonography and color doppler sonography. J Urol 151:1535–1538

    PubMed  CAS  Google Scholar 

  • Mehta AL, Dogra VS (1998) Intratesticular varicocele. J Clin Ultrasound 26:49–51

    Article  PubMed  CAS  Google Scholar 

  • Morvay Z, Nagy E (1998) The diagnosis and treatment of intratesticular varicocele. Cardiovasc Intervent Radiol 21:76–78

    Article  PubMed  CAS  Google Scholar 

  • Naughton CK, Nangia AK, Agarwal A (2001) Pathophysiology of varicoceles in male infertility. Hum Reprod Update 7:473–481

    Article  PubMed  CAS  Google Scholar 

  • Niedzielski J, Paduch D, Raczynski P (1997) Assessment of adolescent varicocele. Pediatr Surg Int 12:410–413

    Article  PubMed  CAS  Google Scholar 

  • O’Donnell PG, Dewbury KC (1998) The ultrasound appearances of intratesticular varicocoele. Br J Radiol 71:324–325

    PubMed  Google Scholar 

  • Oyen RH (2002) Scrotal ultrasound. Eur Radiol 12:19–34

    Article  PubMed  Google Scholar 

  • Ozcan H, Aytac S, Yagci C et al (1997) Color doppler ultrasonographic findings in intratesticular varicocele. J Clin Ultrasound 25:325–329

    Article  PubMed  CAS  Google Scholar 

  • Pearl MS, Hill MC (2007) Ultrasound of the scrotum. Semin Ultrasound CT MR 28:225–248

    Article  PubMed  Google Scholar 

  • Petros JA, Andriole GL, Middleton WD et al (1991) Correlation of testicular color doppler ultrasonography, physical examination and venography in the detection of left varicoceles in men with infertility. J Urol 145:785–788

    PubMed  CAS  Google Scholar 

  • Ross JA, Watson NE Jr, Jarow JP (1994) The effect of varicoceles on testicular blood flow in man. Urology 44:535–539

    Article  PubMed  CAS  Google Scholar 

  • Sakamoto H, Ogawa Y, Yoshida H (2008) Relationship between testicular volume and varicocele in patients with infertility. Urology 71:104–109

    Article  PubMed  Google Scholar 

  • Sarteschi LM, Paoli R, Bianchini M et al (1993) Lo studio del varicocele con eco-color doppler. G Ital Ultrasonologia 4:43–49

    Google Scholar 

  • Sarteschi LM, Liguori G, Trombetta C (2003) Varicocele. In: Sarteschi LM, Menchini-Fabris GF (eds) Ecografia andrologica, 1st edn edn. Athena Srl, Modena, pp 139–155

    Google Scholar 

  • Shafik A, Moftah A, Olfat S et al (1990) Testicular veins: anatomy and role in varicocelogenesis and other pathologic conditions. Urology 35:175–182

    Article  PubMed  CAS  Google Scholar 

  • Shiraishi K, Naito K, Takihara H (2003) Indication of varicocelectomy in the era of assisted reproductive technology: prediction of treatment outcome by noninvasive diagnostic methods. Arch Androl 49:475–478

    Article  PubMed  CAS  Google Scholar 

  • Sigman M, Jarow JP (1997) Ipsilateral testicular hypotrophy is associated with decreased sperm counts in infertile men with varicoceles. J Urol 158:605–607

    Article  PubMed  CAS  Google Scholar 

  • Sweeney TE, Rozum JS, Desjardins C et al (1991) Microvascular pressure distribution in the hamster testis. Am J Physiol 260:H1581–H1589

    PubMed  CAS  Google Scholar 

  • Tanriverdi O, Miroglu C, Horasanli K et al (2006) Testicular blood flow measurements and mean resistive index values after microsurgical and high ligation varicocelectomy. Urology 67:1262–1265

    Article  PubMed  Google Scholar 

  • Tarhan S, Gumus B, Gunduz I et al (2003) Effect of varicocele on testicular artery blood flow in men–color doppler investigation. Scand J Urol Nephrol 37:38–42

    Article  PubMed  Google Scholar 

  • Tasci AI, Resim S, Caskurlu T et al (2001) Color doppler ultrasonography and spectral analysis of venous flow in diagnosis of varicocele. Eur Urol 39:316–321

    Article  PubMed  CAS  Google Scholar 

  • Tetreau R, Julian P, Lyonnet D et al (2007) Intratesticular varicocele: an easy diagnosis but unclear physiopathologic characteristics. J Ultrasound Med 26:1767–1773

    PubMed  Google Scholar 

  • Trum JW, Gubler FM, Laan R et al (1996) The value of palpation, varicoscreen contact thermography and colour doppler ultrasound in the diagnosis of varicocele. Hum Reprod 11:1232–1235

    PubMed  CAS  Google Scholar 

  • Ünsal A, Turgut AT, Taşkin F et al (2007) Resistance and pulsatility index increase in capsular branches of testicular artery: Indicator of impaired testicular microcirculation in varicocele? J Clin Ultrasound 35:191–195

    Article  PubMed  Google Scholar 

  • Varma MK, Ho VB, Haggerty M et al (1998) MR venography as a diagnostic tool in the assessment of recurrent varicocele in an adolescent. Pediatr Radiol 28:636–637

    Article  PubMed  CAS  Google Scholar 

  • von Heijne A (1997) Recurrent varicocele. Demonstration by 3D phase-contrast MR angiography. Acta Radiol 38:1020–1022

    Google Scholar 

  • Weiss AJ, Kellman GM, Middleton WD et al (1992) Intratesticular varicocele: sonographic findings in two patients. Am J Roentgenol 158:1061–1063

    CAS  Google Scholar 

  • Winkelbauer FW, Ammann ME, Karnel F et al (1994) Doppler sonography of varicocele: long-term follow-up after venography and transcatheter sclerotherapy. J Ultrasound Med 13:953–958

    PubMed  CAS  Google Scholar 

  • Yilmaz C, Arslan M (2009) Intrascrotal arteriovenous malformation simulating varicocele. Am J Roentgenol 192:W351

    Article  Google Scholar 

  • Zini A, Buckspan M, Berardinucci D et al (1997) The influence of clinical and subclinical varicocele on testicular volume. Fertil Steril 68:671–674

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michele Bertolotto .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Liguori, G., Bucci, S., Trombetta, C., Brkljačić, B., Bertolotto, M. (2011). Imaging the Infertile Male-1: Varicocele. In: Bertolotto, M., Trombetta, C. (eds) Scrotal Pathology. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2011_191

Download citation

  • DOI: https://doi.org/10.1007/174_2011_191

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-12455-6

  • Online ISBN: 978-3-642-12456-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics