Abstract
Color doppler ultrasound is the imaging modality of choice to evaluate patients with varicocele. In order to assess correctly the extension of the disease and the characteristics of flow, the patient should be examined supine and while standing, at rest and during Valsalva’s maneuver. Several classification can be used to grade varicocele based on position of the dilated vessels and characteristics of flow. Besides color doppler ultrasound spectral analysis is important to assess reflux duration. Experimental studies showed that varicocele causes flow changes in the testicular flows, but investigation in men requires validation. While extratesticular varicocele is relatively common, intratesticular varicocele is rare. Abdominal masses may cause not compressible secondary varicocele. CT and MR imaging are usually not indicated for evaluation of varicocele, but this condition may be recognized in case of examinations performed for other purposes. Scintigraphy and thermography have no current clinical role, while venography is usually performed as a part of percutaneous sclerotherapy.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
World Health Organization (1985) Comparison among different methods for the diagnosis of varicocele. Fertil Steril 43:575–582
Abduljaleel PM, Al-Mulhim F, Nouman A et al (2006) Intratesticular varicocele and extratesticular varicocele in a patient with nephrotic syndrome complicated by left renal vein thrombosis. Ann Saudi Med 26:228–230
Alukal JP, Zurakowski D, Atala A et al (2005) Testicular hypotrophy does not correlate with grade of adolescent varicocele. J Urol 174:2367–2370 discussion 2370
Atasoy C, Fitoz S (2001) Gray-scale and color doppler sonographic findings in intratesticular varicocele. J Clin Ultrasound 29:369–373
Aydos K, Baltaci S, Salih M et al (1993) Use of color doppler sonography in the evaluation of varicoceles. Eur Urol 24:221–225
Basile-Fasolo C, Izzo PL, Canale D et al (1986) Doppler sonography, contact scrotal thermography and venography: a comparative study in evaluation of subclinical varicocele. Int J Fertil 30:62–64
Beddy P, Geoghegan T, Browne RF et al (2005) Testicular varicoceles. Clin Radiol 60:1248–1255
Bhatt S, Rubens DJ, Dogra VS (2006) Sonography of benign intrascrotal lesions. Ultrasound Q 22:121–136
Biagiotti G, Cavallini G, Modenini F et al (2002) Spermatogenesis and spectral echo-colour doppler traces from the main testicular artery. BJU Int 90:903–908
Bucci S, Liguori G, Amodeo A et al (2008) Intratesticular varicocele: evaluation using grey scale and color doppler ultrasound. World J Urol 26:87–89
Callea A, Berardi B, Dilorenzo V et al (1997) Echo-color doppler in the topographic study of varicocele. Arch Ital Urol Androl 69:189–192
Carlsen E, Andersen AG, Buchreitz L et al (2000) Inter-observer variation in the results of the clinical andrological examination including estimation of testicular size. Int J Androl 23:248–253
Chiou RK, Anderson JC, Wobig RK et al (1997) Color Doppler ultrasound criteria to diagnose varicoceles: correlation of a new scoring system with physical examination. Urology 50:953–956
Conti E, Fasolo PP, Sebastiani G et al (2005) Color doppler sonography in the intratesticular varicocele. Arch Ital Urol Androl 77:63–65
Cornud F, Belin X, Amar E et al (1999) Varicocele: strategies in diagnosis and treatment. Eur Radiol 9:536–545
Das KM, Prasad K, Szmigielski W et al (1999) Intratesticular varicocele: evaluation using conventional and doppler sonography. Am J Roentgenol 173:1079–1083
Dee KE, Deck AJ, Waitches GM (2000) Intratesticular pseudoaneurysm after blunt trauma. Am J Roentgenol 174:1136
DemIrbas M, Ellergezen A, BI CY et al (2001) Intratesticular varicocele treated with percutaneous embolization. Urology 58:1058
Diamond DA, Roth JA, Cilento BG et al (2004) Intratesticular varicocele in adolescents: a reversible anechoic lesion of the testis. J Urol 171:381–383
Dogra VS, Gottlieb RH, Oka M et al (2003) Sonography of the scrotum. Radiology 227:18–36
Dubin L, Amelar RD (1970) Varicocele size and results of varicocelectomy in selected subfertile men with varicocele. Fertil Steril 21:606–609
Erdogan N, Ekmekcioglu O, Baykara M (2003) Bilateral intratesticular varicocele in a patient with a history of bilateral cryptorchidism. Turk J Med Sci 33:117–119
Eskew LA, Watson NE, Wolfman N et al (1993) Ultrasonographic diagnosis of varicoceles. Fertil Steril 60:693–697
Gat Y, Zukerman ZV, Bachar GN et al (2003) Adolescent varicocele: is it a unilateral disease? Urology 62:742–746 discussion 746–747
Gat Y, Bachar GN, Zukerman Z et al (2004) Varicocele: a bilateral disease. Fertil Steril 81:424–429
Gat Y, Zukerman Z, Chakraborty J et al (2005) Varicocele, hypoxia and male infertility. Fluid Mechanics analysis of the impaired testicular venous drainage system. Hum Reprod 20:2614–2619
Geatti O, Gasparini D, Shapiro B (1991) A comparison of scintigraphy, thermography, ultrasound and phlebography in grading of clinical varicocele. J Nucl Med 32:2092–2097
Gonda RL Jr, Karo JJ, Forte RA et al (1987) Diagnosis of subclinical varicocele in infertility. Am J Roentgenol 148:71–75
Graif M, Hauser R, Hirshebein A et al (2000) Varicocele and the testicular-renal venous route: hemodynamic doppler sonographic investigation. J Ultrasound Med 19:627–631
Grasso Leanza F, Pepe P, Panella P et al (1997) Volocimetric evaluation of spermatic vessels with echo color doppler in patients with idiopathic varicocele. Minerva Urol Nefrol 49:179–182
Hargreave TB, Liakatas J (1991) Physical examination for varicocele. Br J Urol 67:328
Harrison RM, Lewis RW, Roberts JA (1983) Testicular blood flow and fluid dynamics in monkeys with surgically induced varicoceles. J Androl 4:256–260
Harrison RM, Lewis RW, Roberts JA (1986) Pathophysiology of varicocele in nonhuman primates: long-term seminal and testicular changes. Fertil Steril 46:500–510
Hirsh AV, Cameron KM, Tyler JP et al (1980) The Doppler assessment of varicoceles and internal spermatic vein reflux in infertile men. Br J Urol 52:50–56
Hoekstra T, Witt MA (1995) The correlation of internal spermatic vein palpability with ultrasonographic diameter and reversal of venous flow. J Urol 153:82–84
Hsu HS, Chang LS, Chen MT et al (1994) Decreased blood flow and defective energy metabolism in the varicocele-bearing testicles of rats. Eur Urol 25:71–75
Hussein AF (2006) The role of color doppler ultrasound in prediction of the outcome of microsurgical subinguinal varicocelectomy. J Urol 176:2141–2145
Jarow JP (2001) Effects of varicocele on male fertility. Hum Reprod Update 7:59–64
Liguori G, Trombetta C, Garaffa G et al (2004) Color doppler ultrasound investigation of varicocele. World J Urol 22:378–381
Liguori G, Ollandini G, Pomara G et al (2010) Role of renospermatic basal reflow and age on semen quality improvement after sclerotization of varicocele. Urology 75:1074–1078
Lund L, Nielsen AH (1994) Color doppler sonography in the assessment of varicocele testis. Scand J Urol Nephrol 28:281–285
Marks JL, McMahon R, Lipshultz LI (1986) Predictive parameters of successful varicocele repair. J Urol 136:609–612
Marsman JW (1985) Clinical versus subclinical varicocele: venographic findings and improvement of fertility after embolization. Radiology 155:635–638
Meacham RB, Townsend RR, Rademacher D et al (1994) The incidence of varicoceles in the general population when evaluated by physical examination, gray scale sonography and color doppler sonography. J Urol 151:1535–1538
Mehta AL, Dogra VS (1998) Intratesticular varicocele. J Clin Ultrasound 26:49–51
Morvay Z, Nagy E (1998) The diagnosis and treatment of intratesticular varicocele. Cardiovasc Intervent Radiol 21:76–78
Naughton CK, Nangia AK, Agarwal A (2001) Pathophysiology of varicoceles in male infertility. Hum Reprod Update 7:473–481
Niedzielski J, Paduch D, Raczynski P (1997) Assessment of adolescent varicocele. Pediatr Surg Int 12:410–413
O’Donnell PG, Dewbury KC (1998) The ultrasound appearances of intratesticular varicocoele. Br J Radiol 71:324–325
Oyen RH (2002) Scrotal ultrasound. Eur Radiol 12:19–34
Ozcan H, Aytac S, Yagci C et al (1997) Color doppler ultrasonographic findings in intratesticular varicocele. J Clin Ultrasound 25:325–329
Pearl MS, Hill MC (2007) Ultrasound of the scrotum. Semin Ultrasound CT MR 28:225–248
Petros JA, Andriole GL, Middleton WD et al (1991) Correlation of testicular color doppler ultrasonography, physical examination and venography in the detection of left varicoceles in men with infertility. J Urol 145:785–788
Ross JA, Watson NE Jr, Jarow JP (1994) The effect of varicoceles on testicular blood flow in man. Urology 44:535–539
Sakamoto H, Ogawa Y, Yoshida H (2008) Relationship between testicular volume and varicocele in patients with infertility. Urology 71:104–109
Sarteschi LM, Paoli R, Bianchini M et al (1993) Lo studio del varicocele con eco-color doppler. G Ital Ultrasonologia 4:43–49
Sarteschi LM, Liguori G, Trombetta C (2003) Varicocele. In: Sarteschi LM, Menchini-Fabris GF (eds) Ecografia andrologica, 1st edn edn. Athena Srl, Modena, pp 139–155
Shafik A, Moftah A, Olfat S et al (1990) Testicular veins: anatomy and role in varicocelogenesis and other pathologic conditions. Urology 35:175–182
Shiraishi K, Naito K, Takihara H (2003) Indication of varicocelectomy in the era of assisted reproductive technology: prediction of treatment outcome by noninvasive diagnostic methods. Arch Androl 49:475–478
Sigman M, Jarow JP (1997) Ipsilateral testicular hypotrophy is associated with decreased sperm counts in infertile men with varicoceles. J Urol 158:605–607
Sweeney TE, Rozum JS, Desjardins C et al (1991) Microvascular pressure distribution in the hamster testis. Am J Physiol 260:H1581–H1589
Tanriverdi O, Miroglu C, Horasanli K et al (2006) Testicular blood flow measurements and mean resistive index values after microsurgical and high ligation varicocelectomy. Urology 67:1262–1265
Tarhan S, Gumus B, Gunduz I et al (2003) Effect of varicocele on testicular artery blood flow in men–color doppler investigation. Scand J Urol Nephrol 37:38–42
Tasci AI, Resim S, Caskurlu T et al (2001) Color doppler ultrasonography and spectral analysis of venous flow in diagnosis of varicocele. Eur Urol 39:316–321
Tetreau R, Julian P, Lyonnet D et al (2007) Intratesticular varicocele: an easy diagnosis but unclear physiopathologic characteristics. J Ultrasound Med 26:1767–1773
Trum JW, Gubler FM, Laan R et al (1996) The value of palpation, varicoscreen contact thermography and colour doppler ultrasound in the diagnosis of varicocele. Hum Reprod 11:1232–1235
Ünsal A, Turgut AT, Taşkin F et al (2007) Resistance and pulsatility index increase in capsular branches of testicular artery: Indicator of impaired testicular microcirculation in varicocele? J Clin Ultrasound 35:191–195
Varma MK, Ho VB, Haggerty M et al (1998) MR venography as a diagnostic tool in the assessment of recurrent varicocele in an adolescent. Pediatr Radiol 28:636–637
von Heijne A (1997) Recurrent varicocele. Demonstration by 3D phase-contrast MR angiography. Acta Radiol 38:1020–1022
Weiss AJ, Kellman GM, Middleton WD et al (1992) Intratesticular varicocele: sonographic findings in two patients. Am J Roentgenol 158:1061–1063
Winkelbauer FW, Ammann ME, Karnel F et al (1994) Doppler sonography of varicocele: long-term follow-up after venography and transcatheter sclerotherapy. J Ultrasound Med 13:953–958
Yilmaz C, Arslan M (2009) Intrascrotal arteriovenous malformation simulating varicocele. Am J Roentgenol 192:W351
Zini A, Buckspan M, Berardinucci D et al (1997) The influence of clinical and subclinical varicocele on testicular volume. Fertil Steril 68:671–674
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Liguori, G., Bucci, S., Trombetta, C., Brkljačić, B., Bertolotto, M. (2011). Imaging the Infertile Male-1: Varicocele. In: Bertolotto, M., Trombetta, C. (eds) Scrotal Pathology. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2011_191
Download citation
DOI: https://doi.org/10.1007/174_2011_191
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-12455-6
Online ISBN: 978-3-642-12456-3
eBook Packages: MedicineMedicine (R0)