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The Infertile Male-1: Clinical Features

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Scrotal Pathology

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

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Abstract

Male infertility affects 10% of couples and is treatable in many cases. The evaluation of infertility is initiated typically after 1 year of failure to conceive. Clinical evaluation of the infertile man requires a complete medical history, physical examination, and laboratory studies in order to identify and treat correctable causes of subfertility and recognize those who are candidates for assisted reproductive technologies, those who are sterile and should consider adoption or artificial insemination using donor sperm, and those who should undergo genetic screening. Although pregnancies can be achieved without any evaluation other than a semen analysis, this test alone is insufficient to adequately evaluate the male patient. Treatment of correctable male-factor pathology is cost effective, does not increase the risk of multiple births, and can spare the woman invasive procedures and potential complications associated with assisted reproductive technologies.

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References

  • Bhasin S (2007) Approach to the infertile man. J Clin Endocrinol Metab 92:1995–2004

    Article  PubMed  CAS  Google Scholar 

  • de Vries JW, Repping S, Oates R et al (2001) Absence of deleted in azoospermia (DAZ) genes in spermatozoa of infertile men with somatic DAZ deletions. Fertil Steril 75:476–479

    Article  PubMed  Google Scholar 

  • Evers JH, Collins J, Clarke J (2009) Surgery or embolisation for varicoceles in subfertile men. Cochrane Database Syst Rev:CD000479

    Google Scholar 

  • Ficarra V, Cerruto MA, Liguori G et al (2006) Treatment of varicocele in subfertile men: the cochrane review–a contrary opinion. Eur Urol 49:258–263

    Article  PubMed  Google Scholar 

  • Foresta C, Moro E, Ferlin A (2001) Y chromosome microdeletions and alterations of spermatogenesis. Endocr Rev 22:226–239

    Article  PubMed  CAS  Google Scholar 

  • Francavilla F, Santucci R, Barbonetti A et al (2007) Naturally-occurring antisperm antibodies in men: interference with fertility and clinical implications. An update. Front Biosci 12:2890–2911

    Article  PubMed  CAS  Google Scholar 

  • Gnoth C, Godehardt E, Frank-Herrmann P et al (2005) Definition and prevalence of subfertility and infertility. Hum Reprod 20:1144–1147

    Article  PubMed  CAS  Google Scholar 

  • Goldstein M, Eid JF (1989) Elevation of intratesticular and scrotal skin surface temperature in men with varicocele. J Urol 142:743–745

    PubMed  CAS  Google Scholar 

  • Honig SC, Lipshultz LI, Jarow J (1994) Significant medical pathology uncovered by a comprehensive male infertility evaluation. Fertil Steril 62:1028–1034

    PubMed  CAS  Google Scholar 

  • Jarow JP, Coburn M, Sigman M (1996) Incidence of varicoceles in men with primary and secondary infertility. Urology 47:73–76

    Article  PubMed  CAS  Google Scholar 

  • Kolettis PN (2003) Evaluation of the subfertile man. Am Fam Physician 67:2165–2172

    PubMed  Google Scholar 

  • Liguori G, Ollandini G, Pomara G et al (2010) Role of renospermatic basal reflow and age on semen quality improvement after sclerotization of varicocele. Urology 75:1074–1078

    Article  PubMed  Google Scholar 

  • Page DC, Silber S, Brown LG (1999) Men with infertility caused by AZFc deletion can produce sons by intracytoplasmic sperm injection, but are likely to transmit the deletion and infertility. Hum Reprod 14:1722–1726

    Article  PubMed  CAS  Google Scholar 

  • Rowe T (2006) Fertility and a woman’s age. J Reprod Med 51:157–163

    PubMed  Google Scholar 

  • Rowe PJ, Comhaire FH, Hargreave TB et al (1993) WHO manual for the standardized investigation diagnosis and management of the infertile male. Cambridge University Press, New York

    Google Scholar 

  • Schiff JD, Li PS, Goldstein M (2006) Correlation of ultrasound-measured venous size and reversal of flow with Valsalva with improvement in semen-analysis parameters after varicocelectomy. Fertil Steril 86:250–252

    Article  PubMed  Google Scholar 

  • Schlegel PN (1997) Is assisted reproduction the optimal treatment for varicocele-associated male infertility? A cost-effectiveness analysis. Urology 49:83–90

    Article  PubMed  CAS  Google Scholar 

  • Shefi S, Turek PJ (2006) Definition and current evaluation of subfertile men. Int Braz J Urol 32:385–397

    Article  PubMed  Google Scholar 

  • Sigman M, Lipshultz LI, Howards SS (1997) Evaluation of the subfertile male. In: Lipshultz SSHLI (ed) Infertility in the male, 3rd edn. Mosby, St. Louis, pp 173–193

    Google Scholar 

  • Steckel J, Dicker AP, Goldstein M (1993) Relationship between varicocele size and response to varicocelectomy. J Urol 149:769–771

    PubMed  CAS  Google Scholar 

  • Templeton A (2000) Infertility and the establishment of pregnancy–overview. Br Med Bull 56:577–587

    Article  PubMed  CAS  Google Scholar 

  • Trombetta C, Liguori G, Bucci S et al (2003) Percutaneous treatment of varicocele. Urol Int 70:113–118

    Article  PubMed  Google Scholar 

  • Tulloch WS (1955) Varicocele in subfertility; results of treatment. Br Med J 2:356–358

    Article  PubMed  CAS  Google Scholar 

  • Turek PJ (2005) Practical approaches to the diagnosis and management of male infertility. Nat Clin Pract Urol 2:226–238

    Article  PubMed  Google Scholar 

  • Turek PJ (2008) Male infertility. In: Tanagho EA, McAninch JW (eds) Smith’s general urology, 17th edn. McGraw-Hill, New York, pp 684–716

    Google Scholar 

  • Wilcox AJ, Weinberg CR, Baird DD (1995) Timing of sexual intercourse in relation to ovulation. Effects on the probability of conception, survival of the pregnancy, and sex of the baby. N Engl J Med 333:1517–1521

    Article  PubMed  CAS  Google Scholar 

  • World Health Organization (1987) Towards more objectivity in diagnosis and management of male infertility. Int J Androl 7(Suppl 1):1–53

    Google Scholar 

  • World Health Organization (1999) WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction. Cambridge University Press, Cambridge

    Google Scholar 

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Correspondence to Carlo Trombetta .

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© 2011 Springer-Verlag Berlin Heidelberg

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Liguori, G. et al. (2011). The Infertile Male-1: Clinical Features. In: Bertolotto, M., Trombetta, C. (eds) Scrotal Pathology. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2011_186

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  • DOI: https://doi.org/10.1007/174_2011_186

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-12455-6

  • Online ISBN: 978-3-642-12456-3

  • eBook Packages: MedicineMedicine (R0)

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