Cancers of the Colon, Rectum, and Anus

  • Jonathan B. Ashman
  • Matthew D. Callister
  • Michael G Haddock
  • Leonard L. Gunderson
Part of the Medical Radiology book series (MEDRAD)


Patients with lower gastrointestinal cancer frequently require multidisciplinary management. Concurrent radiotherapy and chemotherapy is often used as an adjuvant to surgical resection in selected patients with resectable but high-risk rectal cancer. In patients with locally unresectable rectal and colon cancer, preoperative chemoradiation is preferably used as a component of the definitive procedure. For patients with anal cancer, concurrent chemoradiation has replaced abdominoperineal resection as the principal form of treatment. Appropriate radiotherapeutic management of the patient with lower gastrointestinal cancer includes proper patient selection and diagnostic evaluation, close cooperation by all physicians participating in the patient’s care, and the use of proper radiotherapeutic techniques. The introduction of intensity modulated radiation therapy (IMRT) into the treatment of both rectal and anal cancer provides the potential for reducing toxicity and improving tumor control with dose escalation.


Rectal Cancer Planning Target Volume Intensity Modulate Radiation Therapy Clinical Target Volume Gross Tumor Volume 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Jonathan B. Ashman
    • 1
  • Matthew D. Callister
    • 1
  • Michael G Haddock
    • 2
  • Leonard L. Gunderson
    • 1
  1. 1.Department of Radiation OncologyMayo Clinic College of Medicine and Mayo ClinicPhoenixUSA
  2. 2.Department of Radiation OncologyMayo Clinic College of Medicine and Mayo ClinicRochesterUSA

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