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Carcinoma of the Vagina

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Technical Basis of Radiation Therapy

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Primary vaginal cancer is a rare entity representing about 2% of all female genital neoplasias and only 0.1–0.2% of all cancers (Jemal et al. 59(4):225–249, 2009). Most carcinomas found in the vagina represent direct extension or metastasis from other primary gynecologic (cervix or vulva) and non-gynecologic sites, most commonly breast and gastrointestinal tract. There are a number of controversies in terms of epidemiology, staging, and diagnostic evaluation as well as in the management of vaginal cancer. Because of its rarity, there is a lack of prospective, randomized studies in patients with vaginal cancer, and therefore it is difficult to establish strong, evidence based-recommendations. Decisions regarding therapeutic options are for the most part, based on retrospective data and individual assessment using general principles derived from clinical experience in the cancer management in other sites. Most of the available data refer to the treatment of primary invasive SCC of the vagina, since this represents the most common histology.

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Authors and Affiliations

  1. Department of Radiation Oncology, Indiana University School of Medicine, 535 Barnhill Drive, RT 041, Indianapolis, IN, 46202, USA

    Higinia R. Cardenes, Jennifer E. Zook & David L. Andolino

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  1. Higinia R. Cardenes
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  2. Jennifer E. Zook
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  3. David L. Andolino
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Correspondence to Higinia R. Cardenes .

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Editors and Affiliations

  1. Institutet Stockholm Sweden, MMC 436, Dept.of Oncol-Pathol Karolinska, Delaware St. SE 420, Minneapolis, 55455, Minnesota, USA

    Seymour H. Levitt

  2. UC Davis Cancer Center, Dept. Radiation Oncology, University of California, Davis, X Street 4501, Sacramento, 95817, California, USA

    James A. Purdy

  3. School of Medicine, Dept. Radiation Oncology, Washington University, Forest Park Ave. 4511, St. Louis, 63108-2138, Michigan, USA

    Carlos A. Perez

  4. Instituut Verbeeten, Tilburg, 5042 SB, Netherlands

    Philip Poortmans

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Cardenes, H.R., Zook, J.E., Andolino, D.L. (2011). Carcinoma of the Vagina. In: Levitt, S., Purdy, J., Perez, C., Poortmans, P. (eds) Technical Basis of Radiation Therapy. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2011_157

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